IN2015DN02938A - - Google Patents

Info

Publication number
IN2015DN02938A
IN2015DN02938A IN2938DEN2015A IN2015DN02938A IN 2015DN02938 A IN2015DN02938 A IN 2015DN02938A IN 2938DEN2015 A IN2938DEN2015 A IN 2938DEN2015A IN 2015DN02938 A IN2015DN02938 A IN 2015DN02938A
Authority
IN
India
Prior art keywords
present disclosure
biophotonic compositions
useful
methods
skin
Prior art date
Application number
Other languages
English (en)
Inventor
Nikolaos Loupis
Remigio Piergallini
Original Assignee
Klox Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/830,488 external-priority patent/US20130281913A1/en
Application filed by Klox Technologies Inc filed Critical Klox Technologies Inc
Publication of IN2015DN02938A publication Critical patent/IN2015DN02938A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22Peroxides; Oxygen; Ozone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0616Skin treatment other than tanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0033Blends of pigments; Mixtured crystals; Solid solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26Optical properties
    • A61K2800/262Transparent; Translucent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42Colour properties
    • A61K2800/43Pigments; Dyes
    • A61K2800/434Luminescent, Fluorescent; Optical brighteners; Photosensitizers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/81Preparation or application process involves irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • A61N2005/0647Applicators worn by the patient the applicator adapted to be worn on the head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • A61N2005/0663Coloured light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)
  • Cosmetics (AREA)
IN2938DEN2015 2012-09-14 2013-09-13 IN2015DN02938A (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261701510P 2012-09-14 2012-09-14
US201261701502P 2012-09-14 2012-09-14
US201261701513P 2012-09-14 2012-09-14
US201361766611P 2013-02-19 2013-02-19
US13/830,488 US20130281913A1 (en) 2012-04-20 2013-03-14 Biophotonic compositions and methods for providing biophotonic treatment
PCT/CA2013/000395 WO2013155620A1 (en) 2012-04-20 2013-04-19 Biophotonic compositions, kits and methods
GB1307157.6A GB2499921B (en) 2012-04-20 2013-04-19 Biophotonic compositions, kits and methods
US201361873791P 2013-09-04 2013-09-04
PCT/CA2013/000786 WO2014040176A1 (en) 2012-09-14 2013-09-13 Chromophore combinations for biophotonic uses

Publications (1)

Publication Number Publication Date
IN2015DN02938A true IN2015DN02938A (es) 2015-09-18

Family

ID=50277449

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2938DEN2015 IN2015DN02938A (es) 2012-09-14 2013-09-13

Country Status (14)

Country Link
US (1) US20190133908A1 (es)
EP (3) EP3329938B1 (es)
JP (3) JP2015528472A (es)
KR (3) KR20210072827A (es)
CN (1) CN104755101B (es)
AU (1) AU2013315303B2 (es)
BR (1) BR112015005382A2 (es)
HK (2) HK1208807A1 (es)
IL (1) IL237657A0 (es)
IN (1) IN2015DN02938A (es)
MX (1) MX367670B (es)
RU (1) RU2015113595A (es)
WO (1) WO2014040176A1 (es)
ZA (1) ZA201501700B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5478631B2 (ja) 2008-11-07 2014-04-23 クロクス テクノロジーズ インコーポレイテッド 創傷治癒のための酸化剤および光活性化剤の組み合わせ
NZ598266A (en) 2009-07-17 2014-03-28 Klox Technologies Inc Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
EP3366274A1 (en) * 2012-09-14 2018-08-29 KLOX Technologies, Inc. Cosmetic biophotonic compositions
EP3329938B1 (en) * 2012-09-14 2021-06-23 KLOX Technologies, Inc. Chromophore combinations for biophotonic uses
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
AU2014286868B2 (en) 2013-07-03 2019-12-19 Klox Technologies Inc. Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds
AR099941A1 (es) 2014-04-01 2016-08-31 Klox Tech Inc Composiciones para relleno de tejido y métodos de uso
US20170106013A1 (en) * 2014-06-04 2017-04-20 Klox Technologies Inc. Biophotonic hydrogels
CA2951513A1 (en) 2014-06-09 2015-12-17 Klox Technologies Inc. Silicone-based biophotonic compositions and uses thereof
MA40518A (fr) * 2014-09-15 2016-03-24 Klox Tech Inc Matrices polymères émissives
US11421349B2 (en) * 2014-10-31 2022-08-23 Klox Technologies Inc. Photoactivatable fibers and fabric media
JP2016172705A (ja) * 2015-03-17 2016-09-29 国立大学法人 東京大学 Mint3阻害剤
AU2017207536A1 (en) * 2016-01-11 2018-07-26 Vetoquinol Sa Biophotonic compositions for treating skin and soft tissue wounds having either or both non-resistant and resistant infections
US20190106573A1 (en) * 2016-05-20 2019-04-11 Howard Hughes Medical Institute Photoactive fluorophores and methods of in vivo labeling
US20190224317A1 (en) * 2016-09-23 2019-07-25 Klox Technologies Inc. Biophotonic compositions and methods for reducing scarring
US11207408B2 (en) 2016-09-23 2021-12-28 Klox Technologies Inc. Biophotonic compositions, methods, and kits for inhibiting and disrupting biofilms
RU2019126650A (ru) * 2017-01-27 2021-03-01 Клокс Текнолоджиз Инк. Способы фотобиомодуляции биологических процессов с использованием флуоресценции, генерируемой и испускаемой от биофотонной композиции или биофотонной системы
WO2019095073A1 (en) * 2017-11-17 2019-05-23 Klox Technologies Limited Modulation of biophotonic regimens
US20210170027A1 (en) * 2017-11-17 2021-06-10 Klox Technologies Limited Biophotonic compositions, methods and kits for enhancing hair growth
US10322297B1 (en) * 2018-08-21 2019-06-18 Lumia Group, LLC Electrically passive low-level light therapy system and methods incorporating same

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US4320140A (en) * 1980-10-09 1982-03-16 Sterling Drug Inc. Synergistic insecticidal compositions
US4647578A (en) * 1983-12-02 1987-03-03 Sterling Drug Inc. Phototoxic insecticidal compositions and method of use thereof
JP2001509831A (ja) * 1997-02-03 2001-07-24 チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド 有機支持材料に共有結合された蛍光発色団
US8974363B2 (en) * 1997-12-11 2015-03-10 Provectus Pharmatech, Inc. Topical medicaments and methods for photodynamic treatment of disease
US6676655B2 (en) * 1998-11-30 2004-01-13 Light Bioscience L.L.C. Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen
ATE406157T1 (de) * 1999-08-13 2008-09-15 Provectus Pharmatech Inc Verbesserte topische medikamente sowie verfahren zur photodynamischer behandlung von krankheiten
US20050008892A1 (en) * 2002-02-01 2005-01-13 Hiroshi Yamamoto Fluorescent compositions comprising diketopyrrolopyrroles
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US7344701B2 (en) * 2004-02-03 2008-03-18 Biosearch Technologies, Inc. Xanthene dyes
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US20100266989A1 (en) * 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
JP5478631B2 (ja) * 2008-11-07 2014-04-23 クロクス テクノロジーズ インコーポレイテッド 創傷治癒のための酸化剤および光活性化剤の組み合わせ
NZ598266A (en) * 2009-07-17 2014-03-28 Klox Technologies Inc Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease
GB201200490D0 (en) * 2012-01-12 2012-02-22 Univ Bath Wound dressing
US11116841B2 (en) * 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
US20130281913A1 (en) * 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
EP3329938B1 (en) * 2012-09-14 2021-06-23 KLOX Technologies, Inc. Chromophore combinations for biophotonic uses

Also Published As

Publication number Publication date
IL237657A0 (en) 2015-04-30
AU2013315303B2 (en) 2018-07-26
KR20150068358A (ko) 2015-06-19
HK1212592A1 (zh) 2016-06-17
KR20210072827A (ko) 2021-06-17
BR112015005382A2 (pt) 2019-11-26
EP2895194A1 (en) 2015-07-22
MX367670B (es) 2019-08-30
HK1208807A1 (en) 2016-03-18
EP3329938B1 (en) 2021-06-23
MX2015003361A (es) 2015-10-22
EP3153177A1 (en) 2017-04-12
JP2018076343A (ja) 2018-05-17
ZA201501700B (en) 2016-01-27
KR20180110240A (ko) 2018-10-08
WO2014040176A1 (en) 2014-03-20
EP2895194A4 (en) 2016-03-09
JP2022003081A (ja) 2022-01-11
CN104755101B (zh) 2018-10-02
RU2015113595A (ru) 2016-11-10
EP3329938A1 (en) 2018-06-06
JP2015528472A (ja) 2015-09-28
US20190133908A1 (en) 2019-05-09
AU2013315303A1 (en) 2015-03-19
CN104755101A (zh) 2015-07-01

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