MX361058B - Método para detectar células tumorales circulantes 5t4-positivas y métodos de diagnóstico de cáncer 5t4-positivo en un sujeto mamífero. - Google Patents
Método para detectar células tumorales circulantes 5t4-positivas y métodos de diagnóstico de cáncer 5t4-positivo en un sujeto mamífero.Info
- Publication number
- MX361058B MX361058B MX2014008928A MX2014008928A MX361058B MX 361058 B MX361058 B MX 361058B MX 2014008928 A MX2014008928 A MX 2014008928A MX 2014008928 A MX2014008928 A MX 2014008928A MX 361058 B MX361058 B MX 361058B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- positive
- mammalian subject
- detecting
- tumor cells
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 208000005443 Circulating Neoplastic Cells Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 208000037819 metastatic cancer Diseases 0.000 abstract 1
- 208000011575 metastatic malignant neoplasm Diseases 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70589—CD45
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Sampling And Sample Adjustment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La presente invención se refiere a métodos para detectar células tumorales circulantes 5T4-positivas en un sujeto mamífero; se proveen métodos de diagnosticar cáncer 5T4-positivo en un sujeto mamífero; los métodos de detección o diagnóstico indican la presencia de cáncer metastásico 5T4-positivo o cáncer 5T4-positivo de etapa temprana.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261590066P | 2012-01-24 | 2012-01-24 | |
US201361753665P | 2013-01-17 | 2013-01-17 | |
PCT/IB2013/050547 WO2013111054A1 (en) | 2012-01-24 | 2013-01-22 | Methods for detecting 5t4-positive circulating tumor cells and methods of diagnosis of 5t4-positive cancer in a mammalian subject |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014008928A MX2014008928A (es) | 2014-10-24 |
MX361058B true MX361058B (es) | 2018-11-23 |
Family
ID=47844410
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014008928A MX361058B (es) | 2012-01-24 | 2013-01-22 | Método para detectar células tumorales circulantes 5t4-positivas y métodos de diagnóstico de cáncer 5t4-positivo en un sujeto mamífero. |
Country Status (15)
Country | Link |
---|---|
US (1) | US10254286B2 (es) |
EP (1) | EP2807485B1 (es) |
JP (1) | JP6254951B2 (es) |
KR (1) | KR101716555B1 (es) |
CN (1) | CN104094116B (es) |
AU (2) | AU2013213301A1 (es) |
BR (1) | BR112014018192A8 (es) |
CA (1) | CA2861437C (es) |
ES (1) | ES2724232T3 (es) |
HK (1) | HK1202923A1 (es) |
IL (1) | IL233543B (es) |
IN (1) | IN2014DN07019A (es) |
MX (1) | MX361058B (es) |
RU (1) | RU2646498C2 (es) |
WO (1) | WO2013111054A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3045918B1 (en) | 2009-10-21 | 2017-12-06 | The Scripps Research Institute | Method of using non-rare cells to detect rare cells |
US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
EP3702785A1 (en) * | 2013-12-30 | 2020-09-02 | The Scripps Research Institute | Circulating tumor cell diagnostics for lung cancer |
EP3100047B1 (en) | 2014-01-27 | 2021-08-11 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for prostate cancer biomarkers |
EP3108246B1 (en) * | 2014-02-21 | 2019-10-09 | Epic Sciences, Inc. | Methods for analyzing rare circulating cells |
WO2015155345A1 (en) * | 2014-04-11 | 2015-10-15 | Medimmune Limited | Antibodies and antibody-drug conjugates |
EP3140656B1 (en) * | 2014-05-09 | 2021-02-17 | The Scripps Research Institute | Compositions and methods for fluid biopsy of melanoma |
JP6657509B2 (ja) * | 2014-08-25 | 2020-03-04 | クリエイティブ マイクロテック インコーポレイテッドCreatv Microtech, Inc. | 疾患の検出及び診断のための血液中の循環細胞バイオマーカーの使用並びにそれらを単離する方法 |
EP3286565A1 (en) * | 2015-04-21 | 2018-02-28 | Genentech, Inc. | Compositions and methods for prostate cancer analysis |
KR102045069B1 (ko) * | 2016-02-23 | 2019-11-15 | 노을 주식회사 | 패치를 이용하는 ctc 진단 방법 및 장치 |
KR102406596B1 (ko) * | 2016-02-23 | 2022-06-10 | 노을 주식회사 | 패치를 이용하는 ctc 진단 방법 및 장치 |
KR20170099739A (ko) | 2016-02-23 | 2017-09-01 | 노을 주식회사 | 접촉식 염색 보조 패치, 그 제조 방법 및 이를 이용하는 염색 방법 |
US10371610B2 (en) | 2016-02-23 | 2019-08-06 | Noul Co., Ltd. | Contact-type patch, staining method using the same, and manufacturing method thereof |
BR112019018767A2 (pt) | 2017-04-03 | 2020-05-05 | Hoffmann La Roche | anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, usos, método para tratar uma doença em um indivíduo e invenção |
WO2019005902A1 (en) * | 2017-06-27 | 2019-01-03 | Qcdx, Llc | SYSTEM AND METHODS FOR DIAGNOSING QUANTITATIVE LIQUID BIOPSY |
CN107918013A (zh) * | 2017-09-25 | 2018-04-17 | 浙江天科高新技术发展有限公司 | 化学发光酶免测定循环肿瘤细胞中K‑Ras蛋白的方法及试剂盒 |
JP2019195304A (ja) | 2018-05-10 | 2019-11-14 | 学校法人順天堂 | 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法 |
WO2020086882A1 (en) * | 2018-10-24 | 2020-04-30 | Northwestern University | Tumor cell aggregation inhibitors' for treating cancer |
JP7381003B2 (ja) * | 2019-04-26 | 2023-11-15 | 学校法人順天堂 | 疾患解析を支援する方法、装置、及びコンピュータプログラム、並びにコンピュータアルゴリズムを訓練する方法、装置、及びプログラム |
US20230175073A1 (en) | 2021-12-07 | 2023-06-08 | Epic Sciences, Inc. | Enhanced characterization of breast cancer |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
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US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
EP0403559A1 (en) | 1988-03-04 | 1990-12-27 | Cancer Research Campaign Technology Limited | Improvements relating to antigens |
US5869053A (en) | 1988-03-04 | 1999-02-09 | Cancer Research Campaign Technology, Ltd. | 5T4 antigen from human trophoblasts |
EP1717248A1 (en) | 1997-06-04 | 2006-11-02 | Oxford Biomedica (UK) Limited | Tumor targeted vector |
JP2003515323A (ja) | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | 抗 体 |
GB0126378D0 (en) | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
US7305112B2 (en) | 2002-10-15 | 2007-12-04 | The Scripps Research Institute | Method of converting rare cell scanner image coordinates to microscope coordinates using reticle marks on a sample media |
BRPI0515113A (pt) * | 2004-09-10 | 2008-07-01 | Wyeth Corp | anticorpos anti-5t4 humanizados e conjugados de anticorpo anti-5t4/caliqueamicina |
US20090317836A1 (en) | 2006-01-30 | 2009-12-24 | The Scripps Research Institute | Methods for Detection of Circulating Tumor Cells and Methods of Diagnosis of Cancer in Mammalian Subject |
AU2007226696C1 (en) | 2006-03-10 | 2016-02-04 | Wyeth Llc | Anti-5T4 antibodies and uses thereof |
WO2008131048A2 (en) | 2007-04-16 | 2008-10-30 | Cellpoint Diagnotics, Inc. | Devices and methods for diagnosing, prognosing, or theranosing a condition by enriching rare cells |
GB0822836D0 (en) * | 2008-12-15 | 2009-01-21 | Oxford Biomedica Ltd | Method |
CA2756493C (en) | 2009-03-24 | 2019-07-02 | Biocept, Inc. | Devices and methods of cell capture and analysis |
WO2010111659A1 (en) | 2009-03-27 | 2010-09-30 | Wyeth Llc | Tumor-initiating cells and methods for using same |
JP2013504064A (ja) | 2009-09-03 | 2013-02-04 | ザ スクリプス リサーチ インスティチュート | 循環腫瘍細胞を分類する方法 |
EP3045918B1 (en) | 2009-10-21 | 2017-12-06 | The Scripps Research Institute | Method of using non-rare cells to detect rare cells |
KR20130043104A (ko) * | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
JP5951603B2 (ja) * | 2010-07-07 | 2016-07-13 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガンThe Regents Of The University Of Michigan | 乳がんの診断および治療 |
CN103517719B (zh) | 2011-04-01 | 2016-10-12 | 惠氏有限责任公司 | 抗体-药物缀合物 |
-
2013
- 2013-01-22 CN CN201380006333.9A patent/CN104094116B/zh not_active Expired - Fee Related
- 2013-01-22 EP EP13708526.2A patent/EP2807485B1/en active Active
- 2013-01-22 KR KR1020147020394A patent/KR101716555B1/ko active IP Right Grant
- 2013-01-22 MX MX2014008928A patent/MX361058B/es active IP Right Grant
- 2013-01-22 WO PCT/IB2013/050547 patent/WO2013111054A1/en active Application Filing
- 2013-01-22 RU RU2014127474A patent/RU2646498C2/ru active
- 2013-01-22 US US14/374,083 patent/US10254286B2/en not_active Expired - Fee Related
- 2013-01-22 IN IN7019DEN2014 patent/IN2014DN07019A/en unknown
- 2013-01-22 AU AU2013213301A patent/AU2013213301A1/en not_active Abandoned
- 2013-01-22 BR BR112014018192A patent/BR112014018192A8/pt not_active Application Discontinuation
- 2013-01-22 ES ES13708526T patent/ES2724232T3/es active Active
- 2013-01-22 JP JP2014553836A patent/JP6254951B2/ja not_active Expired - Fee Related
- 2013-01-22 CA CA2861437A patent/CA2861437C/en not_active Expired - Fee Related
-
2014
- 2014-07-07 IL IL233543A patent/IL233543B/en active IP Right Grant
-
2015
- 2015-04-08 HK HK15103408.3A patent/HK1202923A1/xx not_active IP Right Cessation
-
2018
- 2018-08-24 AU AU2018220154A patent/AU2018220154A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MX2014008928A (es) | 2014-10-24 |
BR112014018192A8 (pt) | 2021-03-02 |
EP2807485B1 (en) | 2019-03-13 |
IL233543B (en) | 2018-02-28 |
AU2018220154A1 (en) | 2018-09-13 |
KR20140100580A (ko) | 2014-08-14 |
IN2014DN07019A (es) | 2015-04-10 |
EP2807485A1 (en) | 2014-12-03 |
HK1202923A1 (en) | 2015-10-09 |
JP2015507190A (ja) | 2015-03-05 |
CA2861437C (en) | 2018-08-21 |
CA2861437A1 (en) | 2013-08-01 |
WO2013111054A1 (en) | 2013-08-01 |
RU2014127474A (ru) | 2016-03-20 |
US20150017661A1 (en) | 2015-01-15 |
JP6254951B2 (ja) | 2017-12-27 |
US10254286B2 (en) | 2019-04-09 |
CN104094116A (zh) | 2014-10-08 |
ES2724232T3 (es) | 2019-09-09 |
CN104094116B (zh) | 2017-05-31 |
IL233543A0 (en) | 2014-08-31 |
RU2646498C2 (ru) | 2018-03-05 |
AU2013213301A1 (en) | 2014-07-17 |
KR101716555B1 (ko) | 2017-03-14 |
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