MX336476B - Terapia anti-angiogenesis para el tratamiento de cancer de mama previamente tratado. - Google Patents

Terapia anti-angiogenesis para el tratamiento de cancer de mama previamente tratado.

Info

Publication number
MX336476B
MX336476B MX2012001745A MX2012001745A MX336476B MX 336476 B MX336476 B MX 336476B MX 2012001745 A MX2012001745 A MX 2012001745A MX 2012001745 A MX2012001745 A MX 2012001745A MX 336476 B MX336476 B MX 336476B
Authority
MX
Mexico
Prior art keywords
treatment
breast cancer
previously treated
angiogenesis therapy
treated breast
Prior art date
Application number
MX2012001745A
Other languages
English (en)
Other versions
MX2012001745A (es
Inventor
Rajeshwari Swamy
Julie Hambleton
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2012001745A publication Critical patent/MX2012001745A/es
Publication of MX336476B publication Critical patent/MX336476B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06QINFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00Commerce
    • G06Q30/02Marketing; Price estimation or determination; Fundraising
    • G06Q30/0241Advertisements
    • G06Q30/0251Targeted advertisements
    • G06Q30/0269Targeted advertisements based on user profile or attribute
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06QINFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q50/00Systems or methods specially adapted for specific business sectors, e.g. utilities or tourism
    • G06Q50/10Services
    • G06Q50/22Social work
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06QINFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q99/00Subject matter not provided for in other groups of this subclass
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

La presente invención se refiere a un anticuerpo anti-VEGF en la manufactura de un medicamento para tratar a un paciente diagnosticado con cáncer de mama triple negativo metastásico previamente tratado, en donde el paciente debió haber recibido una quimioterapia para la enfermedad metastásica en un tratamiento de primera línea, en donde el paciente es sometido a un régimen de tratamiento que combina una quimioterapia como una terapia de segunda línea para tratar el cáncer de mama metastásico previamente tratado con la administración de una cantidad efectiva de un anticuerpo anti-VEGF, que comprende una región variable de cadena pesada que tiene la siguiente secuencia de aminoácidos (SEQ ID NO. 1), y una región variable de cadena ligera que comprende la siguiente secuencia de aminoácidos: (SEQ ID NO. 2), en donde la quimioterapia del régimen de tratamiento en la terapia de segunda línea comprende la administración de al menos un agente quimioterapéutico, seleccionado del grupo que consiste en terapia con taxano, capecitabina, gemcitabina y vinorelbina, y en donde el régimen de tratamiento extiende efecgtivamente la supervivencia libre de progreso del paciente.
MX2012001745A 2009-08-15 2010-08-11 Terapia anti-angiogenesis para el tratamiento de cancer de mama previamente tratado. MX336476B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23428109P 2009-08-15 2009-08-15
US26634309P 2009-12-03 2009-12-03
PCT/US2010/045147 WO2011022264A1 (en) 2009-08-15 2010-08-11 Anti-angiogenesis therapy for the treatment of previously treated breast cancer

Publications (2)

Publication Number Publication Date
MX2012001745A MX2012001745A (es) 2012-03-21
MX336476B true MX336476B (es) 2016-01-20

Family

ID=42830354

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012001745A MX336476B (es) 2009-08-15 2010-08-11 Terapia anti-angiogenesis para el tratamiento de cancer de mama previamente tratado.

Country Status (21)

Country Link
US (2) US20110047103A1 (es)
EP (2) EP3090758A1 (es)
JP (2) JP6088246B2 (es)
KR (1) KR20120107069A (es)
CN (1) CN102573909A (es)
AR (1) AR077848A1 (es)
AU (2) AU2010284446A1 (es)
BR (1) BR112012003346A2 (es)
CA (1) CA2771086A1 (es)
CL (1) CL2012000387A1 (es)
CO (1) CO6612209A2 (es)
CR (1) CR20120076A (es)
IL (1) IL218007A0 (es)
MA (1) MA33579B1 (es)
MX (1) MX336476B (es)
NZ (1) NZ598131A (es)
RU (1) RU2576027C2 (es)
SG (2) SG178419A1 (es)
TW (2) TWI451875B (es)
WO (1) WO2011022264A1 (es)
ZA (1) ZA201200998B (es)

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US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
RU2744860C2 (ru) 2015-12-30 2021-03-16 Кодиак Сайенсиз Инк. Антитела и их конъюгаты
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CN111050784B (zh) * 2017-08-11 2024-03-19 伊利诺伊大学理事会 截短的豚鼠l-天冬酰胺酶变体及其使用方法
CA3157509A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder

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Also Published As

Publication number Publication date
TW201431558A (zh) 2014-08-16
JP2013501801A (ja) 2013-01-17
JP2016117718A (ja) 2016-06-30
MX2012001745A (es) 2012-03-21
BR112012003346A2 (pt) 2016-11-16
WO2011022264A1 (en) 2011-02-24
AR077848A1 (es) 2011-09-28
SG178419A1 (en) 2012-04-27
TWI451875B (zh) 2014-09-11
RU2576027C2 (ru) 2016-02-27
RU2012109932A (ru) 2013-09-20
US20110047103A1 (en) 2011-02-24
JP6088246B2 (ja) 2017-03-01
AU2016202976A1 (en) 2016-05-26
EP3090758A1 (en) 2016-11-09
CR20120076A (es) 2012-05-29
TW201109032A (en) 2011-03-16
ZA201200998B (en) 2013-05-29
MA33579B1 (fr) 2012-09-01
KR20120107069A (ko) 2012-09-28
AU2010284446A1 (en) 2012-03-08
CL2012000387A1 (es) 2012-10-05
CO6612209A2 (es) 2013-02-01
IL218007A0 (en) 2012-04-30
EP2464381A1 (en) 2012-06-20
CA2771086A1 (en) 2011-02-24
US20150071924A1 (en) 2015-03-12
NZ598131A (en) 2014-08-29
SG194395A1 (en) 2013-11-29
CN102573909A (zh) 2012-07-11

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