MX2022008842A - Proteinas para el tratamiento de trastornos de la funcion de la barrera epitelial. - Google Patents

Proteinas para el tratamiento de trastornos de la funcion de la barrera epitelial.

Info

Publication number
MX2022008842A
MX2022008842A MX2022008842A MX2022008842A MX2022008842A MX 2022008842 A MX2022008842 A MX 2022008842A MX 2022008842 A MX2022008842 A MX 2022008842A MX 2022008842 A MX2022008842 A MX 2022008842A MX 2022008842 A MX2022008842 A MX 2022008842A
Authority
MX
Mexico
Prior art keywords
proteins
barrier function
treatment
therapeutic proteins
epithelial barrier
Prior art date
Application number
MX2022008842A
Other languages
English (en)
Inventor
Toshihiko Takeuchi
Ye Jin
Todd Zachary Desantis
Andrew Wonhee Han
Andrew Whitman Goodyear
Tarunmeet Gujral
Karim Dabbagh
Michi Izumi Willcoxon
Stefanie Banas
Original Assignee
Second Genome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Second Genome Inc filed Critical Second Genome Inc
Publication of MX2022008842A publication Critical patent/MX2022008842A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)

Abstract

La descripción se refiere a proteínas terapéuticas y composiciones farmacéuticas que comprenden dichas proteínas, que son útiles en el tratamiento de diversas enfermedades humanas. En aspectos particulares, las proteínas terapéuticas descritas son útiles para tratar enfermedades inflamatorias gastrointestinales humanas y afecciones gastrointestinales asociadas con la disminución de la función o integridad de la barrera de células epiteliales. Además, las proteínas terapéuticas descritas son útiles para tratar una enfermedad inflamatoria intestinal humana, incluyendo, entre otras, la enfermedad de Crohn y la colitis ulcerosa.
MX2022008842A 2017-04-07 2019-10-07 Proteinas para el tratamiento de trastornos de la funcion de la barrera epitelial. MX2022008842A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762482963P 2017-04-07 2017-04-07
US201762607706P 2017-12-19 2017-12-19
US201762611334P 2017-12-28 2017-12-28

Publications (1)

Publication Number Publication Date
MX2022008842A true MX2022008842A (es) 2022-08-02

Family

ID=63710147

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019012051A MX2019012051A (es) 2017-04-07 2018-04-06 Proteinas para el tratamiento de trastornos de la funcion de la barrera epitelial.
MX2022008842A MX2022008842A (es) 2017-04-07 2019-10-07 Proteinas para el tratamiento de trastornos de la funcion de la barrera epitelial.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2019012051A MX2019012051A (es) 2017-04-07 2018-04-06 Proteinas para el tratamiento de trastornos de la funcion de la barrera epitelial.

Country Status (12)

Country Link
US (3) US11207376B2 (es)
EP (1) EP3606542A4 (es)
JP (2) JP2020516615A (es)
KR (2) KR20230144097A (es)
CN (1) CN110769844A (es)
AU (2) AU2018248324B2 (es)
CA (1) CA3059354A1 (es)
IL (1) IL269853A (es)
MX (2) MX2019012051A (es)
SG (1) SG11201909334TA (es)
TW (1) TWI797116B (es)
WO (1) WO2018187682A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3059354A1 (en) 2017-04-07 2018-10-11 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11666627B2 (en) 2017-04-07 2023-06-06 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
WO2019195859A1 (en) * 2018-04-06 2019-10-10 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
WO2020077010A1 (en) * 2018-10-09 2020-04-16 Second Genome, Inc. Lactococcus lactis expression system for delivering proteins efficacious for the treatment of epithelial barrier function disorders
CN114641493A (zh) * 2019-08-21 2022-06-17 阿斯特捷利康合作创业有限责任公司 使用布雷库单抗治疗克罗恩病
CN113773364B (zh) * 2021-08-25 2023-04-28 无锡市儿童医院 小分子肽及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5552284A (en) 1991-03-29 1996-09-03 Genentech, Inc. Detection of interleukin-8 receptors by nudeic acid hybridization
ES2568938T3 (es) * 2009-04-28 2016-05-05 Vanderbilt University Composiciones y procedimientos de tratamiento de trastornos que implican apoptosis de células epiteliales
GB201117313D0 (en) * 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
JP2014093482A (ja) 2012-11-06 2014-05-19 Toshiba Corp 固体撮像装置の製造方法および固体撮像装置
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2015014973A2 (en) * 2013-07-31 2015-02-05 Institut National De La Recherche Agronomique Use of specific glycoside phosphorylases for the implementation of phosphorolysis or reverse phosphorolysis reactions
CA2988693A1 (en) * 2015-06-15 2016-12-22 4D Pharma Research Limited Compositions comprising bacterial strains
CA3059354A1 (en) 2017-04-07 2018-10-11 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11666627B2 (en) * 2017-04-07 2023-06-06 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11174293B2 (en) 2017-06-02 2021-11-16 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders

Also Published As

Publication number Publication date
US20200148728A1 (en) 2020-05-14
US20240066095A1 (en) 2024-02-29
US10251933B2 (en) 2019-04-09
EP3606542A1 (en) 2020-02-12
TW201841649A (zh) 2018-12-01
MX2019012051A (es) 2020-02-12
AU2018248324A1 (en) 2019-10-31
KR20230144097A (ko) 2023-10-13
JP2024037834A (ja) 2024-03-19
CN110769844A (zh) 2020-02-07
AU2023202844A1 (en) 2023-07-06
WO2018187682A1 (en) 2018-10-11
SG11201909334TA (en) 2019-11-28
EP3606542A4 (en) 2021-01-20
IL269853A (en) 2019-11-28
CA3059354A1 (en) 2018-10-11
US11207376B2 (en) 2021-12-28
KR20200003821A (ko) 2020-01-10
US20180289770A1 (en) 2018-10-11
JP2020516615A (ja) 2020-06-11
TWI797116B (zh) 2023-04-01
AU2018248324B2 (en) 2023-02-09

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