MX2022007696A - Celulas de levadura y metodos para la produccion de e8,e10-dodecadienil coenzima a, codlemona y derivados de las mismas. - Google Patents

Celulas de levadura y metodos para la produccion de e8,e10-dodecadienil coenzima a, codlemona y derivados de las mismas.

Info

Publication number
MX2022007696A
MX2022007696A MX2022007696A MX2022007696A MX2022007696A MX 2022007696 A MX2022007696 A MX 2022007696A MX 2022007696 A MX2022007696 A MX 2022007696A MX 2022007696 A MX2022007696 A MX 2022007696A MX 2022007696 A MX2022007696 A MX 2022007696A
Authority
MX
Mexico
Prior art keywords
dodecadienyl
codlemone
coenzyme
derivatives
production
Prior art date
Application number
MX2022007696A
Other languages
English (en)
Inventor
Irina Borodina
Carina Holkenbrink
Christer Löfstedt
Baojian Ding
Leonie Wenning
Original Assignee
Biophero Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biophero Aps filed Critical Biophero Aps
Publication of MX2022007696A publication Critical patent/MX2022007696A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02Acyclic compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/30Microbial fungi; Substances produced thereby or obtained therefrom
    • A01N63/32Yeast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a células de levaduras diseñadas por ingeniería genética para la producción de E8,E10-dodecadienil coenzima A, codlemona (E8,E10-dodecadien-1-ol), y opcionalmente sus derivados acetato de E8,E10-dodecadienilo y/o E8,E10-dodecadienal. También se proporcionan métodos para la producción de E8,E10-dodecadienil coenzima A, codlemona (E8,E10-dodecadien-1-ol), y opcionalmente sus derivados acetato de E8,E10-dodecadienilo y/o E8,E10-dodecadienal. También se proporcionan constructos de ácido nucleico útiles para obtener tales células de levadura.
MX2022007696A 2019-12-20 2020-12-18 Celulas de levadura y metodos para la produccion de e8,e10-dodecadienil coenzima a, codlemona y derivados de las mismas. MX2022007696A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19218703 2019-12-20
PCT/EP2020/086975 WO2021123128A1 (en) 2019-12-20 2020-12-18 Yeast cells and methods for production of e8,e10-dodecadienyl coenzyme a, codlemone and derivatives thereof

Publications (1)

Publication Number Publication Date
MX2022007696A true MX2022007696A (es) 2022-09-23

Family

ID=69147428

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022007696A MX2022007696A (es) 2019-12-20 2020-12-18 Celulas de levadura y metodos para la produccion de e8,e10-dodecadienil coenzima a, codlemona y derivados de las mismas.

Country Status (11)

Country Link
EP (1) EP4077636A1 (es)
JP (1) JP2023507647A (es)
KR (1) KR20220118442A (es)
CN (1) CN115103900A (es)
AU (1) AU2020407273A1 (es)
BR (1) BR112022012109A2 (es)
CA (1) CA3161539A1 (es)
CL (1) CL2022001679A1 (es)
IL (1) IL293960A (es)
MX (1) MX2022007696A (es)
WO (1) WO2021123128A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111690587B (zh) * 2019-03-13 2022-10-25 上海凯赛生物技术股份有限公司 一种离心筛选具有高含油率油脂酵母菌株的方法及其应用
CN112410355B (zh) * 2020-11-23 2022-03-25 昆明理工大学 一种酰基辅酶a氧化酶2基因rkacox2及其应用
CA3225388A1 (en) 2021-08-06 2023-02-09 Anders Gabrielsson Method for producing fatty aldehydes and derivatives thereof
WO2023175065A1 (en) 2022-03-16 2023-09-21 Biophero Aps Stabilization of aldehydes and/or an alcohols
WO2024008622A1 (en) 2022-07-04 2024-01-11 FMC Agricultural Solutions A/S Biopesticide composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017027527A2 (pt) * 2015-06-26 2018-09-11 Univ Danmarks Tekniske ?método para a produção de feromônios de mariposas em levedura
PL3555269T3 (pl) * 2016-12-16 2022-12-19 Danmarks Tekniske Universitet Wytwarzanie desaturowanych alkoholi tłuszczowych i desaturowanych octanów acyli tłuszczowych w drożdżach
CN110300799B (zh) 2016-12-16 2024-01-19 丹麦科技大学 在酵母中产生脂肪醇及其衍生物的方法
CN110914442A (zh) * 2017-05-17 2020-03-24 普罗维维股份有限公司 用于产生昆虫信息素及相关化合物的微生物
US20230332096A1 (en) 2019-02-19 2023-10-19 Biophero Aps Methods and cell factories for producing insect pheromones

Also Published As

Publication number Publication date
EP4077636A1 (en) 2022-10-26
AU2020407273A1 (en) 2022-07-14
BR112022012109A2 (pt) 2022-12-13
CL2022001679A1 (es) 2023-02-24
IL293960A (en) 2022-08-01
WO2021123128A1 (en) 2021-06-24
CN115103900A (zh) 2022-09-23
KR20220118442A (ko) 2022-08-25
CA3161539A1 (en) 2021-06-24
JP2023507647A (ja) 2023-02-24

Similar Documents

Publication Publication Date Title
MX2022007696A (es) Celulas de levadura y metodos para la produccion de e8,e10-dodecadienil coenzima a, codlemona y derivados de las mismas.
EP3722438A3 (en) Method for production of moth pheromones in yeast
WO2019126634A3 (en) Targeted integration of nucleic acids
MY194651A (en) Genetically engineered bacterium for the production of isobutylene
WO2018191715A3 (en) Polypeptides with type v crispr activity and uses thereof
MX2019013331A (es) Sistemas de produccion recombinante para policetidos prenilados de la familia de los cannabinoides.
EP4293104A3 (en) Cell-free production of ribonucleic acid
AU2018293281A1 (en) Novel aspartokinase mutant and method for production of L-amino acid using same
SG10201809312QA (en) Nucleic acid synthesis techniques
BR112017023719A2 (pt) planta de tabaco, parte de planta e/ou célula de planta, semente, cultura de planta, produto de tabaco, método para reduzir pon e/ou nnk, método de produção de uma planta e método para produzir um produto de tabaco
EP4325222A3 (en) Nad(p)-dependent responsive enzymes, electrodes and sensors, and methods for making and using the same
MY189932A (en) Recombinant microorganism for improved production of alanine
MX357482B (es) Cepa deficiente en agse.
AU2019279282A1 (en) Modified homoserine dehydrogenase and method for producing homoserine or l-amino acid derived from homoserine using the same
MY192824A (en) Compound targeting il-23a and tnf-alpha and uses thereof
MY193486A (en) Novel 5 ' -inosinic acid dehydrogenase and method preparing 5'-inosinic acid using the same
WO2014169079A3 (en) Increased productivity during fermentation
MX2017015668A (es) Microorganismos recombinante para la produccion mejorada de quimicos finos.
MY191776A (en) Method for preparing electrocompetent yeast cells, and method for using said cells
MX2018015298A (es) Metodo para estabilizar proteinas.
MY191081A (en) Compound targetting il-23a and b-cell activating factor (baff) and uses thereof
MX2023005081A (es) Anticuerpos multiespecificos para dirigirse a cd28 y pd-l1 y metodos de uso de los mismos.
AU2015344324A8 (en) Endoxylanase mutant, enzyme composition for biomass decomposition, and method for producing sugar solution
MX2021006808A (es) Novedosa psicosa-6-fosfato fosfatasa, composicion para la produccion de psicosa que comprende la misma y procedimiento para la produccion de psicosa mediante el uso de la misma.
MX2019014889A (es) Polipeptidos que tienen actividad trehalasa y polinucleotidos que los codifican.