MX2022004631A - Metodos para la preparacion del acido 5-bromo-2-(3-cloropiridin-2- il)-2h-pirazol-3-carboxilico. - Google Patents

Metodos para la preparacion del acido 5-bromo-2-(3-cloropiridin-2- il)-2h-pirazol-3-carboxilico.

Info

Publication number
MX2022004631A
MX2022004631A MX2022004631A MX2022004631A MX2022004631A MX 2022004631 A MX2022004631 A MX 2022004631A MX 2022004631 A MX2022004631 A MX 2022004631A MX 2022004631 A MX2022004631 A MX 2022004631A MX 2022004631 A MX2022004631 A MX 2022004631A
Authority
MX
Mexico
Prior art keywords
pyrazole
pyridin
bromo
chloro
carboxylic acid
Prior art date
Application number
MX2022004631A
Other languages
English (en)
Inventor
Xin Liu
Jianhua Mao
Yanchun Cao
Zhijian Xu
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of MX2022004631A publication Critical patent/MX2022004631A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

En la presente se describen métodos novedosos para sintetizar el ácido 5-bromo-2-(3-cloropiridin-2-il)-2H-pirazol-3-carboxílico a partir de pirazol o derivados de pirazol. En la presente también se describen intermedios de reacción novedosos.
MX2022004631A 2019-10-18 2020-10-16 Metodos para la preparacion del acido 5-bromo-2-(3-cloropiridin-2- il)-2h-pirazol-3-carboxilico. MX2022004631A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962916840P 2019-10-18 2019-10-18
US202062982248P 2020-02-27 2020-02-27
PCT/US2020/055888 WO2021076835A1 (en) 2019-10-18 2020-10-16 Methods for the preparation of 5-bromo-2-(3chloro-pyridin-2-yl)-2h-pyrazole-3-carboxylic acid

Publications (1)

Publication Number Publication Date
MX2022004631A true MX2022004631A (es) 2022-05-24

Family

ID=73198483

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2022004627A MX2022004627A (es) 2019-10-18 2020-10-16 Metodos para la preparacion del acido 5-bromo-2-(3-cloropiridin-2- il)-2h-pirazol-3-carboxilico.
MX2022004631A MX2022004631A (es) 2019-10-18 2020-10-16 Metodos para la preparacion del acido 5-bromo-2-(3-cloropiridin-2- il)-2h-pirazol-3-carboxilico.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2022004627A MX2022004627A (es) 2019-10-18 2020-10-16 Metodos para la preparacion del acido 5-bromo-2-(3-cloropiridin-2- il)-2h-pirazol-3-carboxilico.

Country Status (15)

Country Link
US (2) US20220396560A1 (es)
EP (5) EP4253380A3 (es)
JP (2) JP2022552273A (es)
KR (2) KR20220084347A (es)
CN (2) CN114641471A (es)
AU (2) AU2020366212A1 (es)
BR (2) BR112022007215A2 (es)
HU (2) HUE062237T2 (es)
IL (5) IL291939B2 (es)
MA (2) MA56053A (es)
MX (2) MX2022004627A (es)
PL (3) PL3976589T3 (es)
TW (2) TW202128631A (es)
UY (1) UY38925A (es)
WO (2) WO2021076835A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022007294A2 (pt) * 2019-10-18 2022-07-05 Fmc Corp Métodos para a preparação de ácido 5-bromo-2-(3-cloro-piridin-2-il)-2h-pirazol-3-carboxílico
CN115557931B (zh) * 2022-10-20 2024-05-14 浙江新安化工集团股份有限公司 一种3-溴-1-(3-氯-2-吡啶基)-1h-吡唑-5-甲酸的合成方法

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DE2060816C3 (de) * 1970-12-10 1980-09-04 Merck Patent Gmbh, 6100 Darmstadt 4-Phenylpiperidinderivate Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen enthaltend diese Verbindungen
ME00495B (me) * 2003-01-28 2011-10-10 Du Pont Cijano antranilamidni insekticidi
PE20060285A1 (es) * 2004-03-30 2006-05-08 Aventis Pharma Inc Piridonas sustituidas como inhibidores de pol(adp-ribosa)-polimerasa (parp)
MY140912A (en) * 2004-07-26 2010-01-29 Du Pont Mixtures of anthranilamide invertebrate pest control agents
US7087755B1 (en) * 2004-11-12 2006-08-08 Frontier Scientific, Inc. Substituted pyridines
KR20090090379A (ko) * 2006-12-13 2009-08-25 화이자 프로덕츠 인크. 3-(4-(2,4-디플루오로벤질옥시)-3-브로모-6-메틸-2-옥소피리딘-1(2ｈ)-일)-ｎ,4-디메틸벤즈아미드의 제조 방법
CL2008000979A1 (es) * 2007-04-11 2008-10-17 Sumitomo Chemical Co Proceso para producir un compuesto derivado de 2-piridin-2-il-2h-pirazol-3-fenilamida; compuestos intermediarios; el compuesto en si; composicion plaguicida que contiene a dicho compuesto; uso de dicho compuesto como plaguicida; y metodo para control
JP2008280340A (ja) * 2007-04-12 2008-11-20 Sumitomo Chemical Co Ltd ヒドラジド化合物及びそれを含有する有害節足動物防除剤
JP2009023991A (ja) * 2007-06-20 2009-02-05 Ishihara Sangyo Kaisha Ltd アントラニルアミド系化合物の製造方法
KR20100057637A (ko) * 2007-08-14 2010-05-31 스미또모 가가꾸 가부시끼가이샤 히드라진 화합물의 제조 방법, 그리고 히드라진 화합물의 제조 중간체 및 그 제조 방법
TW201245155A (en) * 2010-09-01 2012-11-16 Du Pont Fungicidal pyrazoles
CN102651485B (zh) * 2011-02-28 2016-03-30 丰田自动车株式会社 可充镁电池、电解液在可充镁电池中的应用、以及用于可充镁电池的电解液
US9475812B2 (en) * 2011-06-04 2016-10-25 Xuanzhu Pharma Co., Ltd. Pyridonaphthyridine type dual PI3K and mTOR inhibitor and its preparation and use
WO2013105100A1 (en) * 2012-01-09 2013-07-18 Symed Labs Limited Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof
CN105669643A (zh) * 2013-12-05 2016-06-15 江西天人生态股份有限公司 一类基于鱼泥丁受体的邻甲酰氨基苯甲酰胺衍生物及其制备方法和用途
EP3131894A1 (en) * 2014-04-14 2017-02-22 Grünenthal GmbH Heteroaryl substituted heterocyclyl sulfones
TW201726128A (zh) * 2015-10-08 2017-08-01 歌林達有限公司 經吡唑基取代之四氫哌喃基碸
BR112018007673A2 (pt) * 2015-10-16 2018-11-06 Univ Rice William M ?análogos de epotilona, métodos de síntese, métodos de tratamento e conjugados de fármaco dos mesmos?
KR102522231B1 (ko) * 2016-12-21 2023-04-14 바이엘 크롭사이언스 악티엔게젤샤프트 2-피리딜에틸카복사미드 유도체의 제조 방법
GB201721969D0 (en) * 2017-12-27 2018-02-07 Bp Oil Int Methods for preparing fuel additives

Also Published As

Publication number Publication date
EP3976591A1 (en) 2022-04-06
EP4043451B1 (en) 2024-02-28
IL298694A (en) 2023-02-01
IL292090A (en) 2022-06-01
EP4219455A1 (en) 2023-08-02
TW202128631A (zh) 2021-08-01
US20220259178A1 (en) 2022-08-18
HUE062237T2 (hu) 2023-10-28
EP4253380A3 (en) 2023-11-15
AU2020366037A1 (en) 2022-04-21
JP2022552272A (ja) 2022-12-15
IL291939B (en) 2022-12-01
IL291939A (en) 2022-06-01
IL294551B2 (en) 2023-05-01
JP2022552273A (ja) 2022-12-15
PL3976589T3 (pl) 2023-07-31
MA56053A (fr) 2022-04-20
HUE062047T2 (hu) 2023-09-28
EP3976589A1 (en) 2022-04-06
CN114650987A (zh) 2022-06-21
EP4043451A1 (en) 2022-08-17
WO2021076835A8 (en) 2021-11-04
AU2020366212A1 (en) 2022-04-21
WO2021076835A1 (en) 2021-04-22
IL294551B1 (en) 2023-01-01
IL291939B2 (en) 2023-04-01
BR112022007102A2 (pt) 2022-07-05
PL4043451T3 (pl) 2024-06-10
IL294551A (en) 2022-09-01
UY38925A (es) 2021-05-31
MX2022004627A (es) 2022-05-26
BR112022007215A2 (pt) 2022-07-05
MA56055A (fr) 2022-04-06
EP4253380A2 (en) 2023-10-04
WO2021076839A1 (en) 2021-04-22
EP3976591B1 (en) 2023-04-19
CN114641471A (zh) 2022-06-17
PL3976591T3 (pl) 2023-07-31
US20220396560A1 (en) 2022-12-15
KR20220086612A (ko) 2022-06-23
EP3976589B1 (en) 2023-04-12
IL299818A (en) 2023-03-01
KR20220084347A (ko) 2022-06-21
IL292090B2 (en) 2023-06-01
TW202116748A (zh) 2021-05-01

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