MX2022003384A - Polimeros que contienen acido fenil boronico sustituido y metodos de uso. - Google Patents

Polimeros que contienen acido fenil boronico sustituido y metodos de uso.

Info

Publication number
MX2022003384A
MX2022003384A MX2022003384A MX2022003384A MX2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A
Authority
MX
Mexico
Prior art keywords
methods
substituted phenyl
boronic acid
acid containing
containing polymers
Prior art date
Application number
MX2022003384A
Other languages
English (en)
Inventor
Thomas Henry Jozefiak
Ashish Nimgaonkar
Steven C Polomoscanik
Original Assignee
Glyscend Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glyscend Inc filed Critical Glyscend Inc
Publication of MX2022003384A publication Critical patent/MX2022003384A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/42—Introducing metal atoms or metal-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F216/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical
    • C08F216/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical by an alcohol radical
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
    • C08F230/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
    • C08F230/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing boron
    • C08F230/065—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing boron the monomer being a polymerisable borane, e.g. dimethyl(vinyl)borane
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F271/00—Macromolecular compounds obtained by polymerising monomers on to polymers of nitrogen-containing monomers as defined in group C08F26/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

La exposición se refiere a polímeros catiónicos funcionalizados con grupos de ácido fenil borónico sustituidos y a métodos para utilizar los mismos para tratar trastornos metabólicos y gastrointestinales.
MX2022003384A 2019-09-20 2020-09-18 Polimeros que contienen acido fenil boronico sustituido y metodos de uso. MX2022003384A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962903328P 2019-09-20 2019-09-20
PCT/US2020/051506 WO2021055759A1 (en) 2019-09-20 2020-09-18 Substituted phenyl boronic acid containing polymers and methods of use

Publications (1)

Publication Number Publication Date
MX2022003384A true MX2022003384A (es) 2022-06-27

Family

ID=74884712

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022003384A MX2022003384A (es) 2019-09-20 2020-09-18 Polimeros que contienen acido fenil boronico sustituido y metodos de uso.

Country Status (11)

Country Link
US (6) US11484548B2 (es)
EP (1) EP4031553A4 (es)
JP (1) JP2022548699A (es)
KR (1) KR20220065812A (es)
CN (1) CN114423768A (es)
AU (1) AU2020348451A1 (es)
BR (1) BR112022004981A2 (es)
CA (1) CA3150057A1 (es)
IL (1) IL291462A (es)
MX (1) MX2022003384A (es)
WO (1) WO2021055759A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4031553A4 (en) 2019-09-20 2023-11-01 Glyscend, Inc. POLYMERS CONTAINING SUBSTITUTED PHENYLBORONIC ACID AND METHODS OF USE

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221425B1 (en) * 1998-01-30 2001-04-24 Advanced Cardiovascular Systems, Inc. Lubricious hydrophilic coating for an intracorporeal medical device
US7998412B2 (en) 2000-01-07 2011-08-16 Smart Holograms Limited Ophthalmic device comprising a holographic sensor
US7041280B2 (en) 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
US7662360B2 (en) 2002-07-22 2010-02-16 Psimei Pharmaceuticals Plc Conjugates of N-hydroxypropymethacrylamide-methacrylate copolymer with nuclide activation agent and/or anti-cancer compounds
US20060134062A1 (en) 2002-11-19 2006-06-22 Huval Chad C Polymeric boronic acid derivatives as lipase inhibitors
GB0305587D0 (en) 2003-03-11 2003-04-16 Smart Holograms Ltd Sensor
CA2575431A1 (en) 2004-07-30 2006-02-02 Basf Ag Polymeric boronic acid derivatives and their use for papermaking
JP2007177014A (ja) 2005-12-27 2007-07-12 Kawamura Inst Of Chem Res ホウ酸塩基含有アリルアミン重合体
WO2008028193A2 (en) * 2006-09-01 2008-03-06 Pharmion Corporation Colon-targeted oral formulations of cytidine analogs
DE602008002592D1 (de) * 2007-05-21 2010-10-28 Lubrizol Advanced Mat Inc Harte, aliphatische thermoplastische Polyurethane
US20110059176A1 (en) * 2007-11-22 2011-03-10 The University Of Tokyo Material for preventing tissue adhesion and material for preventing joint contracture
US8956556B2 (en) * 2008-07-02 2015-02-17 Eaton Corporation Dielectric isolators
JP5622188B2 (ja) * 2010-01-05 2014-11-12 独立行政法人物質・材料研究機構 フェニルボロン酸系単量体及びフェニルボロン酸系重合体
JP5696961B2 (ja) 2010-05-26 2015-04-08 独立行政法人物質・材料研究機構 糖応答性ゲル及び薬剤投与デバイス
JP5398017B2 (ja) 2010-07-22 2014-01-29 国立大学法人 東京大学 検出デバイス及びバイオセンサ
EP2711774B1 (en) 2011-05-20 2017-03-29 Nissan Chemical Industries, Ltd. Photosensitive resin composition
WO2013028548A2 (en) 2011-08-19 2013-02-28 The Regents Of The University Of California Compositions and devices for the detection of biomarkers in the gastrointestinal tract and methods for making and using them
KR101912978B1 (ko) 2011-11-17 2018-10-29 도꾜 다이가꾸 페닐보론산기가 도입된 블록 공중합체 및 그의 용도
US10716802B2 (en) 2013-03-15 2020-07-21 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
WO2015120471A1 (en) 2014-02-10 2015-08-13 The Johns Hopkins University Devices for and methods of treatment of metabolic syndromes
CN103865060B (zh) 2014-03-20 2016-06-29 江南大学 一种含有苯硼酸官能团的高分子助留助滤剂的制备方法及其应用
WO2016154317A2 (en) * 2015-03-23 2016-09-29 Massachusetts Institute Of Technology Polymers, hydrogels, and uses thereof
WO2017024237A1 (en) 2015-08-06 2017-02-09 The Johns Hopkins University Composition and method for treatment of metabolic disorders
US10973846B2 (en) 2015-09-24 2021-04-13 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
WO2017061435A1 (ja) 2015-10-06 2017-04-13 国立研究開発法人物質・材料研究機構 ビニルアルコール樹脂機能化方法並びにビニルアルコール樹脂機能化剤
WO2017070617A1 (en) 2015-10-21 2017-04-27 Case Western Reserve University Diol-modified insulin analogues containing a glucose-regulated conformational switch
US11035080B2 (en) 2015-12-14 2021-06-15 Ecolab Usa Inc. Boronic acid containing polymers for papermaking process
EP3852768A4 (en) * 2018-09-20 2022-09-14 Glyscend, Inc. BORONIC ACID POLYMERS AND METHODS OF USE
EP4031553A4 (en) 2019-09-20 2023-11-01 Glyscend, Inc. POLYMERS CONTAINING SUBSTITUTED PHENYLBORONIC ACID AND METHODS OF USE
EP4041740A4 (en) 2019-09-20 2023-10-25 Glyscend, Inc. BENZOXABOROLE POLYMERS AND METHODS OF USE

Also Published As

Publication number Publication date
US20220265703A1 (en) 2022-08-25
CA3150057A1 (en) 2021-03-25
EP4031553A1 (en) 2022-07-27
US20220088062A1 (en) 2022-03-24
US11576928B2 (en) 2023-02-14
US20220088063A1 (en) 2022-03-24
US20240082297A1 (en) 2024-03-14
AU2020348451A1 (en) 2022-04-21
JP2022548699A (ja) 2022-11-21
US20230338415A1 (en) 2023-10-26
EP4031553A4 (en) 2023-11-01
US11491183B2 (en) 2022-11-08
BR112022004981A2 (pt) 2022-06-21
IL291462A (en) 2022-05-01
WO2021055759A1 (en) 2021-03-25
US11484548B2 (en) 2022-11-01
US20220226366A1 (en) 2022-07-21
CN114423768A (zh) 2022-04-29
KR20220065812A (ko) 2022-05-20
US11491182B2 (en) 2022-11-08

Similar Documents

Publication Publication Date Title
EA201891366A1 (ru) Гуманизированные антитела против cd73
JO3343B1 (ar) أحماض 5- أمينوتتراهيدروكوينولين-2- كربوكسيليك جديدة واستخدامها
MX2022007754A (es) Nuevos agonistas de il2 y metodos de uso de estos.
MX2021005887A (es) Compuestos de 2-formil-3-hidroxifeniloximetilo capaces de modular hemoglobina.
MX2016017271A (es) Moleculas con especificidad para cd45 y cd79.
EA201791007A3 (ru) Соединения и их применения для модуляции гемоглобина
MX2018000147A (es) Moleculas de anticuerpo que se unen al grupo de diferenciacion 45 (cd45).
MY166062A (en) St2l antagonists and methods of use
EA201591426A1 (ru) Соединения и их применения для модуляции гемоглобина
SG10201804385YA (en) Stimulus responsive polymers for the purification of biomolecules
EA201591546A1 (ru) Мультивалентные и моновалентные мультиспецифические комплексы и их применение
MX2019008122A (es) Derivados de aminas heterociclicas que inhiben la transduccion de se?al mediada por cinasa asociada con el receptor de interleucina-1.
EA201591432A1 (ru) Соединения и их применения для модуляции гемоглобина
NZ738538A (en) 6-amino-quinoline-3-carbonitrils as cot modulators
EA201590881A1 (ru) Терапевтические соединения и композиции и их использование в качестве модуляторов пк-m2
MX2015012420A (es) Nuevas proteinas de union para pcsk9.
EA201591399A1 (ru) РАППγ АГОНИСТЫ ДЛЯ ЛЕЧЕНИЯ РАССЕЯННОГО СКЛЕРОЗА
MY191932A (en) Chitosan-derived compositions
GB201101740D0 (en) Therapeutic agents with improved fibrinogen binding
MX2022003384A (es) Polimeros que contienen acido fenil boronico sustituido y metodos de uso.
EA201791318A1 (ru) Дрожжи для приготовления алкогольных напитков
NZ727292A (en) Methods of treating incontinence and other sphincter deficiency disorders
MX2018004164A (es) Inhibidores de sumoilacion de crmp2 y usos de los mismos.
MX2021007271A (es) Nuevas moleculas de acido nucleico conjugado y sus usos.
EA201491522A1 (ru) Способы лечения нарушения походки и/или равновесия у пациентов с рассеянным склерозом с использованием аминопиридина