MX2020005915A - Composiciones en forma de una solución acuosa inyectable que comprende glucagón humano y un copoliaminoácido. - Google Patents
Composiciones en forma de una solución acuosa inyectable que comprende glucagón humano y un copoliaminoácido.Info
- Publication number
- MX2020005915A MX2020005915A MX2020005915A MX2020005915A MX2020005915A MX 2020005915 A MX2020005915 A MX 2020005915A MX 2020005915 A MX2020005915 A MX 2020005915A MX 2020005915 A MX2020005915 A MX 2020005915A MX 2020005915 A MX2020005915 A MX 2020005915A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- aqueous solution
- injectable aqueous
- human glucagon
- copolyamino acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
La invención también se refiere a composiciones físicamente estables en forma de una solución acuosa inyectable, para las cuales el pH está comprendido de 6.0 o 8.0, que comprenden al menos: a) glucagón humano, y b) un copolaminoácido con cargas de carboxilato y radicales hidrofóbicos, En una modalidad, las composiciones de acuerdo con la invención también comprenden una hormona gastrointestinal.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762606137P | 2017-12-07 | 2017-12-07 | |
FR1761809A FR3074683B1 (fr) | 2017-12-07 | 2017-12-07 | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
FR1855939 | 2018-06-29 | ||
PCT/EP2018/084065 WO2019110837A1 (fr) | 2017-12-07 | 2018-12-07 | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020005915A true MX2020005915A (es) | 2020-10-19 |
Family
ID=66750442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020005915A MX2020005915A (es) | 2017-12-07 | 2018-12-07 | Composiciones en forma de una solución acuosa inyectable que comprende glucagón humano y un copoliaminoácido. |
Country Status (7)
Country | Link |
---|---|
US (1) | US20210386830A1 (es) |
IL (1) | IL275184A (es) |
MA (1) | MA51018A (es) |
MX (1) | MX2020005915A (es) |
PH (1) | PH12020550828A1 (es) |
SA (1) | SA520412140B1 (es) |
WO (1) | WO2019110837A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3897570A1 (en) | 2018-12-19 | 2021-10-27 | KRKA, d.d., Novo mesto | Pharmaceutical composition comprising glp-1 analogue |
WO2021123228A1 (en) | 2019-12-18 | 2021-06-24 | Krka, D.D., Novo Mesto | Pharmaceutical composition comprising glp-1 analogue |
EP4091625A1 (en) | 2021-05-22 | 2022-11-23 | Adocia | Compositions comprising short-acting hormones for treating or preventing obesity and pumps comprising said composition |
WO2022248419A2 (en) | 2021-05-22 | 2022-12-01 | Adocia | Compositions comprising short-acting hormones for treating or preventing obesity and pumps comprising said composition |
EP4144362A1 (en) | 2021-09-06 | 2023-03-08 | Adocia | Compositions comprising short-acting hormones for treating or preventing obesity and pumps comprising said composition |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1202607A (en) | 1968-01-10 | 1970-08-19 | Novo Terapeutisk Labor As | Improvements in or relating to stable glucagon solutions and their preparation |
DE69918070T2 (de) | 1998-03-13 | 2005-08-25 | Novo Nordisk A/S | Stabilisierte, wässrige Glukagonlösungen, enthaltend Detergenzien |
FR2801226B1 (fr) | 1999-11-23 | 2002-01-25 | Flamel Tech Sa | Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation |
FR2840614B1 (fr) | 2002-06-07 | 2004-08-27 | Flamel Tech Sa | Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques |
US20110097386A1 (en) | 2009-10-22 | 2011-04-28 | Biodel, Inc. | Stabilized glucagon solutions |
WO2011138802A1 (en) | 2010-05-07 | 2011-11-10 | Sun Pharma Advanced Research Company Ltd., | Injection solution |
EP2635296B1 (en) | 2010-11-03 | 2014-12-24 | Arecor Limited | Novel composition comprising glucagon |
WO2013101749A1 (en) | 2011-12-29 | 2013-07-04 | Latitude Pharmaceuticals, Inc. | Stabilized glucagon nanoemulsions |
CN107583039A (zh) * | 2012-01-09 | 2018-01-16 | 阿道恰公司 | Ph为7且至少含pi为5.8至8.5之基础胰岛素和取代共聚(氨基酸)的可注射溶液 |
WO2014096440A2 (en) | 2012-12-21 | 2014-06-26 | Novozymes Biopharma Dk A/S | Composition |
WO2015095389A1 (en) | 2013-12-18 | 2015-06-25 | Aegis Therapeutics, Llc | Compositions for drug administration |
US9334316B2 (en) | 2014-04-11 | 2016-05-10 | Oregon Health & Science University | Formulations comprising glucagon |
CN109562064A (zh) * | 2016-06-07 | 2019-04-02 | 阿道恰公司 | 包含人胰高血糖素和统计共聚氨基酸的可注射水溶液形式的组合物 |
-
2018
- 2018-12-07 WO PCT/EP2018/084065 patent/WO2019110837A1/fr unknown
- 2018-12-07 MX MX2020005915A patent/MX2020005915A/es unknown
- 2018-12-07 MA MA051018A patent/MA51018A/fr unknown
-
2020
- 2020-06-04 PH PH12020550828A patent/PH12020550828A1/en unknown
- 2020-06-07 IL IL275184A patent/IL275184A/en unknown
- 2020-06-07 SA SA520412140A patent/SA520412140B1/ar unknown
-
2021
- 2021-08-17 US US17/404,547 patent/US20210386830A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
SA520412140B1 (ar) | 2023-02-26 |
US20210386830A1 (en) | 2021-12-16 |
MA51018A (fr) | 2020-10-14 |
WO2019110837A1 (fr) | 2019-06-13 |
PH12020550828A1 (en) | 2021-05-10 |
IL275184A (en) | 2020-07-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2018015070A (es) | Composiciones en forma de solucion acuosa inyectable, que comprende glucagon humano y un co-poliaminoacido injertado en el extremo. | |
PH12020550828A1 (en) | Compositions in the form of an injectable aqueous solution comprising human glucagon and a copolyamino acid | |
PH12018502558A1 (en) | Injectable solution at ph 7, comprising at least one basal insulin whose pi is between 5.8 and 8.5, a prandial insulin and/or a gastrointestinal hormone, and a copolyamino acid bearing carboxylate charges and hydrophobic radicals | |
PH12020550827A1 (en) | Injectable solution at ph 7 comprising at least one basal insulin having a pi of between 5.8 and 8.5 and a copolyamino acid carrying carboxylate charges and hydrophobic radicals | |
MA53356A (fr) | Formulations sous-cutanées d'anticorps anti-cd38 et leurs utilisations | |
WO2019110797A8 (fr) | Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide | |
MX2023011657A (es) | Composiciones que comprenden curones y usos de los mismos. | |
PH12017501486A1 (en) | Nasal powder formulation for treatment of hypoglycemia | |
PH12018502714A1 (en) | Nicotine particles and compositions | |
MX2016005395A (es) | Formulacion estable de insulina glulisina. | |
MY174991A (en) | Eurycoma longifolia extract and its use in enhancing and/or stimulating immune system | |
MX2019005855A (es) | Formulaciones que se pueden pulverizar. | |
PH12020550804A1 (en) | Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a copolyamino acid | |
SG11202005322RA (en) | Injectable solution at ph 7 comprising at least one basal insulin having a pi of between 5.8 and 8.5 and a copolyamino acid carrying carboxylate charges and hydrophobic radicals | |
SG11202005320VA (en) | Compositions in the form of an injectable aqueous solution comprising human glucagon and a copolyamino acid | |
MY193928A (en) | Aqueous primer | |
MX2020006670A (es) | Composicion acuosa que comprende acido 2-(dimetil-1h-pirazol-1-il) succinico y amoniaco. | |
EA202091387A1 (ru) | Композиции в форме инъецируемого водного раствора, содержащие человеческий глюкагон и сополиаминокислоту | |
SG11201804902UA (en) | A composition for improving memory, learning ability, and cognitive ability | |
MY187571A (en) | Krill oil preparations with optimal mineral and metal composition, low impurities and low and stable tma levels | |
PH12019501946A1 (en) | Liquid composition containing pradofloxacin | |
FR3074683B1 (fr) | Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon humain et un co-polyaminoacide | |
EP3426043A4 (en) | PLANT-BASED FORMULATION FOR INCREASING THE PH OF THE HUMAN BODY AND MOVING IT FROM AC PH PHASE TO ALKALINE PH |