MX2019012014A - Medicina terapeutica para enfermedades fibrosas. - Google Patents
Medicina terapeutica para enfermedades fibrosas.Info
- Publication number
- MX2019012014A MX2019012014A MX2019012014A MX2019012014A MX2019012014A MX 2019012014 A MX2019012014 A MX 2019012014A MX 2019012014 A MX2019012014 A MX 2019012014A MX 2019012014 A MX2019012014 A MX 2019012014A MX 2019012014 A MX2019012014 A MX 2019012014A
- Authority
- MX
- Mexico
- Prior art keywords
- peptide fragment
- hmgb1 peptide
- specific
- inventors
- present
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
Los presentes inventores descubrieron que un péptido de fragmento de HMGB1 que tiene una secuencia de aminoácidos particular muestra efectos de inhibir la adhesión de los dedos y la cicatrización del tracto digestivo y prolonga la supervivencia en los ratones modelo con epidermólisis ampulosa distrófica. También en el modelo de úlcera de la piel, la administración del péptido de fragmento de HMGB1 específico se encontró que inhibe la fibrosidad de la piel durante el proceso de cicatrización de la úlcera. Basado en estos descubrimientos, la presente solicitud proporciona composiciones farmacéuticas para el tratamiento de enfermedades fibróticas, que comprenden el péptido de fragmento de HMGB1 específico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2017076600 | 2017-04-07 | ||
PCT/JP2018/014662 WO2018186480A1 (ja) | 2017-04-07 | 2018-04-06 | 線維性疾患の治療薬 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019012014A true MX2019012014A (es) | 2019-11-11 |
Family
ID=63713333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012014A MX2019012014A (es) | 2017-04-07 | 2018-04-06 | Medicina terapeutica para enfermedades fibrosas. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20200038486A1 (es) |
EP (1) | EP3607963A4 (es) |
JP (2) | JPWO2018186480A1 (es) |
KR (1) | KR20190135519A (es) |
CN (2) | CN110621331A (es) |
AU (1) | AU2018250076A1 (es) |
BR (1) | BR112019020294A2 (es) |
CA (1) | CA3058877A1 (es) |
MX (1) | MX2019012014A (es) |
RU (1) | RU2019134382A (es) |
WO (1) | WO2018186480A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI805565B (zh) | 2017-01-27 | 2023-06-21 | 日商斯德武利姆股份有限公司 | 心肌病、陳舊性心肌梗塞及慢性心臟衰竭的治療藥物 |
EP3718561A4 (en) | 2017-12-01 | 2021-07-21 | Stemrim Inc. | Therapy for inflammatory bowel disease |
BR112021005982A2 (pt) * | 2018-10-05 | 2021-06-29 | StemRIM Inc. | peptídeo possuindo atividade de mobilização de células-tronco mesenquimais |
CN113423466A (zh) | 2018-10-25 | 2021-09-21 | 国立大学法人大阪大学 | 软骨病症的治疗剂 |
JPWO2020149395A1 (ja) * | 2019-01-18 | 2021-11-25 | 国立大学法人大阪大学 | 栄養障害型表皮水疱症治療薬 |
EP4144359A4 (en) * | 2020-04-03 | 2024-05-01 | Stemrim Inc | PEPTIDE WITH MESENCHYMAL STEM CELL MOBILIZATION ACTIVITY |
WO2023037562A1 (ja) * | 2021-09-07 | 2023-03-16 | 国立大学法人大阪大学 | 肺炎の治療薬 |
WO2023053384A1 (ja) * | 2021-09-30 | 2023-04-06 | 国立大学法人大阪大学 | 脂肪肝および非アルコール性脂肪肝炎の治療薬 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007076200A2 (en) * | 2005-11-28 | 2007-07-05 | Medimmune, Inc. | Antagonists of hmgb1 and/or rage and methods of use thereof |
CA2778759A1 (en) * | 2009-10-28 | 2011-05-05 | Genomix Co., Ltd. | Tissue-regeneration promoter using recruitment of bone marrow mesenchymal stem cells and/or pluripotent stem cells in blood |
CA2834255C (en) * | 2011-04-26 | 2021-11-02 | Genomix Co., Ltd. | Peptide for inducing regeneration of tissue and use thereof |
AU2013335684B2 (en) * | 2012-10-25 | 2017-06-29 | Osaka University | Novel method for treating cardiac infarction using HMGB1 fragment |
GB201508337D0 (en) * | 2015-05-15 | 2015-06-24 | Hmgbiotech S R L | Novel peptides |
TWI805565B (zh) * | 2017-01-27 | 2023-06-21 | 日商斯德武利姆股份有限公司 | 心肌病、陳舊性心肌梗塞及慢性心臟衰竭的治療藥物 |
CN111868231A (zh) * | 2017-12-01 | 2020-10-30 | 斯特姆里姆有限公司 | 外胚层间充质干细胞及其产生方法 |
-
2018
- 2018-04-06 BR BR112019020294-3A patent/BR112019020294A2/pt unknown
- 2018-04-06 JP JP2019511313A patent/JPWO2018186480A1/ja active Pending
- 2018-04-06 KR KR1020197032759A patent/KR20190135519A/ko not_active IP Right Cessation
- 2018-04-06 CA CA3058877A patent/CA3058877A1/en active Pending
- 2018-04-06 US US16/499,604 patent/US20200038486A1/en active Pending
- 2018-04-06 WO PCT/JP2018/014662 patent/WO2018186480A1/ja active Application Filing
- 2018-04-06 CN CN201880023662.7A patent/CN110621331A/zh active Pending
- 2018-04-06 CN CN202311550243.8A patent/CN117618534A/zh active Pending
- 2018-04-06 RU RU2019134382A patent/RU2019134382A/ru unknown
- 2018-04-06 AU AU2018250076A patent/AU2018250076A1/en active Pending
- 2018-04-06 MX MX2019012014A patent/MX2019012014A/es unknown
- 2018-04-06 EP EP18781748.1A patent/EP3607963A4/en active Pending
-
2022
- 2022-12-20 JP JP2022202757A patent/JP2023030070A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN117618534A (zh) | 2024-03-01 |
EP3607963A4 (en) | 2021-01-06 |
RU2019134382A3 (es) | 2021-08-13 |
BR112019020294A2 (pt) | 2020-05-12 |
EP3607963A1 (en) | 2020-02-12 |
KR20190135519A (ko) | 2019-12-06 |
JPWO2018186480A1 (ja) | 2020-02-20 |
WO2018186480A1 (ja) | 2018-10-11 |
AU2018250076A1 (en) | 2019-10-31 |
US20200038486A1 (en) | 2020-02-06 |
RU2019134382A (ru) | 2021-05-07 |
CA3058877A1 (en) | 2018-10-11 |
JP2023030070A (ja) | 2023-03-07 |
CN110621331A (zh) | 2019-12-27 |
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