MX2019002907A - Métodos y composiciones para edición de genoma mediante inducción haploide. - Google Patents

Métodos y composiciones para edición de genoma mediante inducción haploide.

Info

Publication number
MX2019002907A
MX2019002907A MX2019002907A MX2019002907A MX2019002907A MX 2019002907 A MX2019002907 A MX 2019002907A MX 2019002907 A MX2019002907 A MX 2019002907A MX 2019002907 A MX2019002907 A MX 2019002907A MX 2019002907 A MX2019002907 A MX 2019002907A
Authority
MX
Mexico
Prior art keywords
compositions
methods
genome editing
haploid induction
editing via
Prior art date
Application number
MX2019002907A
Other languages
English (en)
Inventor
S Ream Thomas
C Lamb Jonathan
L Armstrong Charles
j cargill Edward
Dong Fenggao
W Larue Huachun
J Lawrence Richard
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of MX2019002907A publication Critical patent/MX2019002907A/es

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/06Processes for producing mutations, e.g. treatment with chemicals or with radiation
    • A01H1/08Methods for producing changes in chromosome number
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213Targeted insertion of genes into the plant genome by homologous recombination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/52Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/57Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/61Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/67Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/68Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/71Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic unsaturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/30Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/20Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Se proveen metodos y composiciones para la reproduccion de plantas mejorada mediante el uso de edicion genica e induccion de haploides.
MX2019002907A 2016-09-14 2017-09-13 Métodos y composiciones para edición de genoma mediante inducción haploide. MX2019002907A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662394409P 2016-09-14 2016-09-14
PCT/US2017/051248 WO2018052919A1 (en) 2016-09-14 2017-09-13 Methods and compositions for genome editing via haploid induction

Publications (1)

Publication Number Publication Date
MX2019002907A true MX2019002907A (es) 2019-09-18

Family

ID=61618901

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019002907A MX2019002907A (es) 2016-09-14 2017-09-13 Métodos y composiciones para edición de genoma mediante inducción haploide.

Country Status (7)

Country Link
US (2) US11401524B2 (es)
EP (1) EP3512329A4 (es)
CN (1) CN109936977A (es)
BR (1) BR112019004850A2 (es)
CA (1) CA3036234A1 (es)
MX (1) MX2019002907A (es)
WO (1) WO2018052919A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107920486B (zh) 2015-06-30 2023-06-20 明尼苏达大学董事会 用于加速基因组编辑的单倍体诱导系
US10519456B2 (en) 2016-12-02 2019-12-31 Syngenta Participations Ag Simultaneous gene editing and haploid induction
CA3042082A1 (en) 2016-12-02 2018-06-07 Syngenta Participations Ag Simultaneous gene editing and haploid induction
US11483991B2 (en) 2018-04-27 2022-11-01 Monsanto Technology, Llc Methods for genotyping haploid embryos
WO2019234129A1 (en) 2018-06-05 2019-12-12 KWS SAAT SE & Co. KGaA Haploid induction with modified dna-repair
CN109122293B (zh) * 2018-08-29 2022-04-05 广西壮族自治区农业科学院玉米研究所 一种利用除草剂加倍玉米单倍体的方法
US20220251588A1 (en) * 2019-08-05 2022-08-11 Monsanto Technology Llc Compositions and methods for chromosome rearrangement
JP2022543824A (ja) * 2019-08-07 2022-10-14 モンサント テクノロジー エルエルシー 植物におけるcast媒介dna標的化
AU2021286555A1 (en) * 2020-06-09 2023-02-02 Cold Spring Harbor Laboratory Heterozygous CENH3 monocots and methods of use thereof for haploid induction and simultaneous genome editing
BR112023002276A2 (pt) * 2020-08-12 2023-03-14 Syngenta Crop Protection Ag Reprodução por cruzamento amplo
AU2021338707A1 (en) * 2020-09-10 2023-04-06 Monsanto Technology Llc Increasing gene editing and site-directed integration events utilizing meiotic and germline promoters
CN113122571A (zh) * 2021-05-27 2021-07-16 华中农业大学 一种新型CRISPR/Cas9基因编辑载体的载体制备方法
CN113455378A (zh) * 2021-08-04 2021-10-01 北大荒垦丰种业股份有限公司 玉米单倍体诱导系的选育方法及其应用
CN115633635A (zh) * 2022-10-09 2023-01-24 武汉市农业科学院 一种基于单倍体育种技术创制甜玉米dh系的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
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MXPA01011541A (es) * 1999-05-17 2002-06-04 Icon Genetics Inc Proceso para una rapida transformacion de plantas independientemente de la variedad.
ATE324434T1 (de) * 1999-08-05 2006-05-15 Icon Genetics Inc Verfahren zur herstellung künstlicher pflanzenchromosomen
US8304233B2 (en) * 2002-06-04 2012-11-06 Poetic Genetics, Llc Methods of unidirectional, site-specific integration into a genome, compositions and kits for practicing the same
US7078234B2 (en) 2002-12-18 2006-07-18 Monsanto Technology Llc Maize embryo-specific promoter compositions and methods for use thereof
US7439416B2 (en) * 2004-01-09 2008-10-21 The Carnegie Institution Of Washington Indeterminate gametophyte 1 (ig1)gene from Zea mays and uses thereof
WO2007014275A2 (en) * 2005-07-26 2007-02-01 Sangamo Biosciences, Inc. Targeted integration and expression of exogenous nucleic acid sequences
BRPI0810083B8 (pt) * 2007-03-28 2020-10-06 Monsanto Technology Llc métodos para estabelecer onde uma planta de soja ou semente de soja deve ser cultivada, de melhoramento da planta de soja, para selecionar uma semente de soja, de distribuição de uma planta de soja, para isolar sementes de soja de maturidade precoce indeterminada, e para determinar se uma planta de soja tem um grupo de maturidade
US8558061B2 (en) * 2008-12-29 2013-10-15 Agrigenetics, Inc. Induced chromosome doubling in plants
MX2012003981A (es) * 2009-10-06 2012-06-12 Univ California Generacion de plantas haploides y cruza de plantas mejorada.
US20110203012A1 (en) * 2010-01-21 2011-08-18 Dotson Stanton B Methods and compositions for use of directed recombination in plant breeding
JP6583918B2 (ja) * 2012-12-27 2019-10-02 キージーン ナムローゼ フェンノートシャップ 植物における遺伝連鎖を解消するための方法
US9677082B2 (en) * 2013-03-15 2017-06-13 Syngenta Participations Ag Haploid induction compositions and methods for use therefor
US11039586B2 (en) * 2013-03-15 2021-06-22 Monsanto Technology Llc Creation and transmission of megaloci
CA2906747A1 (en) * 2013-03-15 2014-09-18 Regents Of The University Of Minnesota Engineering plant genomes using crispr/cas systems
US9681615B2 (en) * 2013-06-20 2017-06-20 Elwha Llc Rapid breeding of plants
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AU2016331020B2 (en) 2015-10-02 2021-04-29 Keygene N.V. Method for the production of haploid and subsequent doubled haploid plants
BR112018006573A2 (pt) 2015-10-02 2018-10-09 método para a produção de plantas haploides e subsequentes haploides duplicadas
WO2018015957A1 (en) * 2016-07-21 2018-01-25 Kaiima Bio Agritech Ltd. Compositions and methods for generating a haploid of a target plant
WO2018015956A1 (en) * 2016-07-21 2018-01-25 Kaiima Bio Agritech Ltd. Compositions and methods for generating a haploid of a target plant
CA3042082A1 (en) 2016-12-02 2018-06-07 Syngenta Participations Ag Simultaneous gene editing and haploid induction

Also Published As

Publication number Publication date
EP3512329A4 (en) 2020-03-04
EP3512329A1 (en) 2019-07-24
WO2018052919A1 (en) 2018-03-22
BR112019004850A2 (pt) 2019-06-11
CN109936977A (zh) 2019-06-25
US20190169596A1 (en) 2019-06-06
CA3036234A1 (en) 2018-03-22
US11401524B2 (en) 2022-08-02
US20220348943A1 (en) 2022-11-03

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