MX2018010847A - Terapia combinada mediante el uso de un conjugado de anticuerpo-farmaco de liv1 (liv1-adc) y agente quimioterapeutico. - Google Patents

Terapia combinada mediante el uso de un conjugado de anticuerpo-farmaco de liv1 (liv1-adc) y agente quimioterapeutico.

Info

Publication number
MX2018010847A
MX2018010847A MX2018010847A MX2018010847A MX2018010847A MX 2018010847 A MX2018010847 A MX 2018010847A MX 2018010847 A MX2018010847 A MX 2018010847A MX 2018010847 A MX2018010847 A MX 2018010847A MX 2018010847 A MX2018010847 A MX 2018010847A
Authority
MX
Mexico
Prior art keywords
chemotherapeutic
liv1
adc
combination therapy
liv
Prior art date
Application number
MX2018010847A
Other languages
English (en)
Inventor
Sussman Django
Kostic Ana
Li Fu
Original Assignee
Seattle Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seattle Genetics Inc filed Critical Seattle Genetics Inc
Publication of MX2018010847A publication Critical patent/MX2018010847A/es

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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61K47/68031—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being an auristatin
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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  • Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Genetics & Genomics (AREA)
  • Oncology (AREA)
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  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención proporciona métodos de tratamiento de un sujeto que tiene o está en riesgo de tener cáncer mediante la administración de un conjugado anticuerpo-fármaco LIV-1 y un agente quimioterapéutico.
MX2018010847A 2016-03-15 2017-03-15 Terapia combinada mediante el uso de un conjugado de anticuerpo-farmaco de liv1 (liv1-adc) y agente quimioterapeutico. MX2018010847A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662308639P 2016-03-15 2016-03-15
US201662317792P 2016-04-04 2016-04-04
US201662367510P 2016-07-27 2016-07-27
PCT/US2017/022541 WO2017161007A1 (en) 2016-03-15 2017-03-15 Combination therapy using a liv1-adc and a chemotherapeutic

Publications (1)

Publication Number Publication Date
MX2018010847A true MX2018010847A (es) 2019-07-04

Family

ID=59852409

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018010847A MX2018010847A (es) 2016-03-15 2017-03-15 Terapia combinada mediante el uso de un conjugado de anticuerpo-farmaco de liv1 (liv1-adc) y agente quimioterapeutico.
MX2023008849A MX2023008849A (es) 2016-03-15 2018-09-07 Terapia combinada mediante el uso de un conjugado de anticuerpo-farmaco de liv1 (liv1-adc) y agente quimioterapeutico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023008849A MX2023008849A (es) 2016-03-15 2018-09-07 Terapia combinada mediante el uso de un conjugado de anticuerpo-farmaco de liv1 (liv1-adc) y agente quimioterapeutico.

Country Status (14)

Country Link
US (2) US11325980B2 (es)
EP (1) EP3429626A4 (es)
JP (2) JP2019508433A (es)
KR (3) KR20220157515A (es)
CN (1) CN108697801A (es)
AU (2) AU2017235545A1 (es)
BR (1) BR112018068129A2 (es)
CA (1) CA3016485A1 (es)
EA (1) EA201891968A1 (es)
IL (1) IL261505A (es)
MA (1) MA45324A (es)
MX (2) MX2018010847A (es)
SG (2) SG10201912908QA (es)
WO (1) WO2017161007A1 (es)

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