MX2018010771A - Moleculas de union al transcrito 7 similar a inmunoglobulina (ilt7) y metodos de uso de las mismas. - Google Patents
Moleculas de union al transcrito 7 similar a inmunoglobulina (ilt7) y metodos de uso de las mismas.Info
- Publication number
- MX2018010771A MX2018010771A MX2018010771A MX2018010771A MX2018010771A MX 2018010771 A MX2018010771 A MX 2018010771A MX 2018010771 A MX2018010771 A MX 2018010771A MX 2018010771 A MX2018010771 A MX 2018010771A MX 2018010771 A MX2018010771 A MX 2018010771A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- binding molecules
- same
- ilt7
- ilt7 binding
- Prior art date
Links
- 101000984199 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily A member 4 Proteins 0.000 abstract 2
- 102100025555 Leukocyte immunoglobulin-like receptor subfamily A member 4 Human genes 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Rehabilitation Therapy (AREA)
- Transplantation (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
Abstract
La presente invención se refiere a moléculas de unión a ILT7, por ejemplo, a anticuerpos de anti-ILT7, y a los métodos para tratar o prevenir las afecciones y enfermedades asociadas con las células que expresan ILT7 tales como las enfermedades autoinmunes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662306125P | 2016-03-10 | 2016-03-10 | |
PCT/US2017/021616 WO2017156298A1 (en) | 2016-03-10 | 2017-03-09 | Ilt7 binding molecules and methods of using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018010771A true MX2018010771A (es) | 2019-05-15 |
Family
ID=59790876
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018010771A MX2018010771A (es) | 2016-03-10 | 2017-03-09 | Moleculas de union al transcrito 7 similar a inmunoglobulina (ilt7) y metodos de uso de las mismas. |
MX2023010076A MX2023010076A (es) | 2016-03-10 | 2018-09-06 | Moleculas de union al transcrito 7 similar a inmunoglobulina (ilt7) y metodos de uso de las mismas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023010076A MX2023010076A (es) | 2016-03-10 | 2018-09-06 | Moleculas de union al transcrito 7 similar a inmunoglobulina (ilt7) y metodos de uso de las mismas. |
Country Status (17)
Country | Link |
---|---|
US (3) | US11072652B2 (es) |
EP (1) | EP3426298A4 (es) |
JP (3) | JP6979976B2 (es) |
KR (4) | KR102632796B1 (es) |
CN (2) | CN114874322A (es) |
AR (2) | AR109450A1 (es) |
AU (1) | AU2017231833B2 (es) |
BR (1) | BR112018067951A2 (es) |
CA (1) | CA3017197A1 (es) |
IL (1) | IL261653A (es) |
MX (2) | MX2018010771A (es) |
RU (1) | RU2756109C2 (es) |
SG (2) | SG11201807523PA (es) |
TW (1) | TWI755380B (es) |
UA (1) | UA127731C2 (es) |
WO (1) | WO2017156298A1 (es) |
ZA (1) | ZA201806597B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102632796B1 (ko) | 2016-03-10 | 2024-02-02 | 비엘라 바이오, 인크. | Ilt7 결합 분자 및 이의 사용 방법 |
US11787858B2 (en) * | 2016-12-22 | 2023-10-17 | Icahn School Of Medicine At Mount Sinai | Anti-LILRB3 antibodies and methods of use thereof |
MX2021012726A (es) * | 2019-04-19 | 2021-11-17 | Allogene Therapeutics Inc | Anticuerpos contra receptores de antigenos quimericos derivados de 4g7. |
JP2023505203A (ja) * | 2019-12-06 | 2023-02-08 | ビエラ バイオ インコーポレイテッド | Ilt7結合タンパク質を使用した治療方法 |
JP2023507369A (ja) * | 2019-12-20 | 2023-02-22 | メディミューン,エルエルシー | グリピカン3を標的とするキメラ抗原受容体を用いて癌を治療する組成物及び方法 |
WO2021203013A2 (en) * | 2020-04-03 | 2021-10-07 | Viela Bio, Inc. | Methods of treating immune mediated pulmonary injury |
JP2024516698A (ja) | 2021-05-04 | 2024-04-16 | ビエラ バイオ インコーポレイテッド | Ilt7結合タンパク質を使用する、自己免疫疾患の治療方法 |
WO2024026388A1 (en) | 2022-07-27 | 2024-02-01 | Viela Bio, Inc. | Formulations comprising an immunoglobulin-like transcript 7 (ilt7)-binding protein |
Family Cites Families (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2096948A (en) | 1935-12-20 | 1937-10-26 | Anchor Steel & Conveyor Co | Conveyer system |
US4741900A (en) | 1982-11-16 | 1988-05-03 | Cytogen Corporation | Antibody-metal ion complexes |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
DE68927933T2 (de) | 1988-09-02 | 1997-08-14 | Dyax Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
IE63847B1 (en) | 1989-05-05 | 1995-06-14 | Res Dev Foundation | A novel antibody delivery system for biological response modifiers |
US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
US5780225A (en) | 1990-01-12 | 1998-07-14 | Stratagene | Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules |
WO1991010737A1 (en) | 1990-01-11 | 1991-07-25 | Molecular Affinities Corporation | Production of antibodies using gene libraries |
SG48759A1 (en) | 1990-01-12 | 2002-07-23 | Abgenix Inc | Generation of xenogenic antibodies |
US5314995A (en) | 1990-01-22 | 1994-05-24 | Oncogen | Therapeutic interleukin-2-antibody based fusion proteins |
US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
US5698426A (en) | 1990-09-28 | 1997-12-16 | Ixsys, Incorporated | Surface expression libraries of heteromeric receptors |
ATE164395T1 (de) | 1990-12-03 | 1998-04-15 | Genentech Inc | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
WO1992018619A1 (en) | 1991-04-10 | 1992-10-29 | The Scripps Research Institute | Heterodimeric receptor libraries using phagemids |
PT1696031E (pt) | 1991-12-02 | 2010-06-25 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
JPH09506262A (ja) | 1993-12-08 | 1997-06-24 | ジェンザイム・コーポレイション | 特異的抗体の製造方法 |
DE69534347T2 (de) | 1994-01-31 | 2006-05-24 | Trustees Of Boston University, Boston | Bibliotheken aus Polyklonalen Antikörpern |
US5516637A (en) | 1994-06-10 | 1996-05-14 | Dade International Inc. | Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage |
DE4440354A1 (de) | 1994-11-11 | 1996-05-15 | Hoechst Schering Agrevo Gmbh | Kombinationen aus Phenylsulfonylharnstoff-Herbiziden und Safenern |
ATE219517T1 (de) | 1995-08-18 | 2002-07-15 | Morphosys Ag | Protein-/(poly)peptidbibliotheken |
US7264963B1 (en) | 1995-08-18 | 2007-09-04 | Morphosys Ag | Protein(poly)peptide libraries |
JP2978435B2 (ja) | 1996-01-24 | 1999-11-15 | チッソ株式会社 | アクリロキシプロピルシランの製造方法 |
US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
ES2353268T3 (es) | 1999-07-02 | 2011-02-28 | Morphosys Ag | Generacion de elementos de union especifica que se unen a (poli)peptidos codificados por fragmentos de adn genomico o est. |
US6849425B1 (en) | 1999-10-14 | 2005-02-01 | Ixsys, Inc. | Methods of optimizing antibody variable region binding affinity |
EP2332579A3 (en) | 2000-02-10 | 2011-09-21 | Abbott Laboratories | Antibodies that bind human interleukin-18 and methods of making and using |
US6897067B2 (en) | 2000-11-03 | 2005-05-24 | Regents Of The University Of Michigan | Surface transfection and expression procedure |
AU2001297872B2 (en) | 2000-11-17 | 2006-11-09 | University Of Rochester | In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells |
WO2003012061A2 (en) * | 2001-08-01 | 2003-02-13 | Coley Pharmaceutical Gmbh | Methods and compositions relating to plasmacytoid dendritic cells |
US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
WO2003081376A2 (en) | 2002-03-20 | 2003-10-02 | Catalina Marketing International Inc. | Targeted incentives based upon predicted behavior |
JP4563171B2 (ja) | 2002-05-24 | 2010-10-13 | シェーリング コーポレイション | 中和ヒト抗igfr抗体 |
WO2004023973A2 (en) | 2002-09-12 | 2004-03-25 | Incyte Corporation | Molecules for diagnostics and therapeutics |
WO2005007800A2 (ja) * | 2003-07-18 | 2005-01-27 | Mochida Pharm Co Ltd | 抗血小板膜糖蛋白質ⅵモノクローナル抗体 |
US9208495B2 (en) | 2003-10-06 | 2015-12-08 | Yellowpages.Com Llc | Methods and apparatuses for advertisement presentation |
GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
KR101363120B1 (ko) | 2005-02-10 | 2014-02-13 | 베일러 리서치 인스티튜트 | 항-인터페론 알파 모노클로날 항체 및 사용 방법 |
WO2006124269A2 (en) * | 2005-05-16 | 2006-11-23 | Amgen Fremont Inc. | Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders |
AU2012244391B2 (en) | 2005-12-20 | 2014-09-11 | Sbi Biotech Co., Ltd. | Anti-ILT7 antibody |
SG10201602095PA (en) * | 2005-12-20 | 2016-05-30 | Sbi Biotech Co Ltd | Anti-Ilt7 Antibody |
EP2010567A2 (en) | 2006-04-07 | 2009-01-07 | The Government of the United States of America as Represented by The Department of Health and Human Services | Antibody compositions and methods for treatment of neoplastic disease |
CA2652599C (en) | 2006-05-03 | 2019-09-24 | Ross Kedl | Cd40 agonist antibody/type1 interferon synergistic adjuvant combination, conjugates containing and use thereof as a therapeutic to enhance cellular immunity |
US7781306B2 (en) | 2007-06-20 | 2010-08-24 | Semiconductor Energy Laboratory Co., Ltd. | Semiconductor substrate and method for manufacturing the same |
US20110311558A1 (en) | 2008-12-01 | 2011-12-22 | The Board Of Regents Of The University Of Texas System | Recombinant Bone Marrow Stromal Antigen-2 in the Treatment of Autoimmune Diseases |
BR112012004781A2 (pt) | 2009-09-03 | 2017-02-14 | Medimmune Llc | diagnóstico de interferon tipo 1 |
US20120316071A1 (en) * | 2009-11-04 | 2012-12-13 | Vaughn Smider | Methods for affinity maturation-based antibody optimization |
AR086074A1 (es) | 2011-04-26 | 2013-11-13 | Genentech Inc | Composiciones y metodo para tratar enfermedades autoinmunes |
ES2861595T3 (es) | 2011-04-28 | 2021-10-06 | Univ Leland Stanford Junior | Identificación de polinucleótidos asociados a una muestra |
US9427464B2 (en) | 2011-11-22 | 2016-08-30 | Chiome Bioscience Inc. | Anti-human TROP-2 antibody having an antitumor activity in vivo |
TR201819828T4 (tr) * | 2012-01-31 | 2019-01-21 | Sbi Biotech Co Ltd | Anti-fosfolipaz d4 antikoru. |
US8605807B1 (en) | 2012-05-22 | 2013-12-10 | Nigel Iain Stuart Macrae | Communicating distinct data over a single frequency using multiple linear polarized signals |
CN104884049A (zh) * | 2012-11-08 | 2015-09-02 | 克莱尔塞德生物医学股份有限公司 | 用于在人类受试者中治疗眼部疾病的方法和装置 |
US9114438B2 (en) | 2013-05-21 | 2015-08-25 | Applied Materials, Inc. | Copper residue chamber clean |
AU2015308625A1 (en) * | 2014-08-29 | 2017-04-20 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind OprF and Oprl |
KR102632796B1 (ko) | 2016-03-10 | 2024-02-02 | 비엘라 바이오, 인크. | Ilt7 결합 분자 및 이의 사용 방법 |
JP2023505203A (ja) | 2019-12-06 | 2023-02-08 | ビエラ バイオ インコーポレイテッド | Ilt7結合タンパク質を使用した治療方法 |
JP2024516698A (ja) | 2021-05-04 | 2024-04-16 | ビエラ バイオ インコーポレイテッド | Ilt7結合タンパク質を使用する、自己免疫疾患の治療方法 |
-
2017
- 2017-03-09 KR KR1020237034385A patent/KR102632796B1/ko active IP Right Grant
- 2017-03-09 MX MX2018010771A patent/MX2018010771A/es unknown
- 2017-03-09 KR KR1020187028675A patent/KR102439395B1/ko active IP Right Grant
- 2017-03-09 US US16/083,825 patent/US11072652B2/en active Active
- 2017-03-09 SG SG11201807523PA patent/SG11201807523PA/en unknown
- 2017-03-09 RU RU2018135550A patent/RU2756109C2/ru active
- 2017-03-09 KR KR1020227029604A patent/KR102603010B1/ko active IP Right Grant
- 2017-03-09 WO PCT/US2017/021616 patent/WO2017156298A1/en active Application Filing
- 2017-03-09 JP JP2018567013A patent/JP6979976B2/ja active Active
- 2017-03-09 UA UAA201810089A patent/UA127731C2/uk unknown
- 2017-03-09 AU AU2017231833A patent/AU2017231833B2/en active Active
- 2017-03-09 CA CA3017197A patent/CA3017197A1/en active Pending
- 2017-03-09 KR KR1020247003436A patent/KR20240017421A/ko not_active Application Discontinuation
- 2017-03-09 CN CN202210535107.0A patent/CN114874322A/zh active Pending
- 2017-03-09 CN CN201780029035.XA patent/CN109414499B/zh active Active
- 2017-03-09 BR BR112018067951A patent/BR112018067951A2/pt unknown
- 2017-03-09 SG SG10202008769SA patent/SG10202008769SA/en unknown
- 2017-03-09 EP EP17764118.0A patent/EP3426298A4/en active Pending
- 2017-03-10 TW TW106107877A patent/TWI755380B/zh active
- 2017-03-29 AR ARP170100775A patent/AR109450A1/es unknown
-
2018
- 2018-09-06 IL IL261653A patent/IL261653A/en unknown
- 2018-09-06 MX MX2023010076A patent/MX2023010076A/es unknown
- 2018-10-04 ZA ZA2018/06597A patent/ZA201806597B/en unknown
-
2021
- 2021-05-28 AR ARP210101444A patent/AR122196A2/es unknown
- 2021-06-17 US US17/350,271 patent/US11673950B2/en active Active
- 2021-11-16 JP JP2021186637A patent/JP7354212B2/ja active Active
-
2023
- 2023-04-21 US US18/305,165 patent/US20230250167A1/en active Pending
- 2023-09-20 JP JP2023151943A patent/JP2024009808A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12019502283A1 (en) | Anti-lag3 antibodies | |
MX2023010076A (es) | Moleculas de union al transcrito 7 similar a inmunoglobulina (ilt7) y metodos de uso de las mismas. | |
EA201890285A1 (ru) | Антитела против pd-1, активируемые антитела против pd-1 и способы их применения | |
PH12018500906A1 (en) | Antibodies specifically binding pd-1 and their uses | |
PH12018500711A1 (en) | Anti-pd1 antibodies and methods of use | |
MX2020009461A (es) | Anticuerpos anti-proteína que contiene dominio de inmunologlubina rfig elacionado con el receptor de poliovirus (pvrig) y métodos de uso. | |
WO2018069500A3 (en) | ANTI-LAG-3 ANTIBODIES AND COMPOSITIONS | |
EP4335874A3 (en) | Anti-hla-g antibodies and use thereof | |
MX2018010295A (es) | Anticuerpos que tienen especificidad para atenuador de linfocitos b y t (btla) y usos de los mismos. | |
PH12017500402A1 (en) | Anti-glucagon antibodies and uses thereof | |
EA201890131A1 (ru) | Иммуномодуляция и лечение солидных опухолей антителами, которые специфически связывают cd38 | |
MX2017014955A (es) | Agentes de union a inmunorreceptor de celulas t con dominios ig y motivo de inhibicion basado en tirosina de inmunorreceptor (tigit) y usos de los mismos. | |
EP4219561A3 (en) | Anti-cd38 antibodies for treatment of light chain amyloidosis and other cd38-positive hematological malignancies | |
WO2017015622A3 (en) | Gdf11 binding proteins and uses thereof | |
EA201891539A1 (ru) | Соединения, ингибирующие металлоферменты | |
AU2016263598A8 (en) | Methods and kits for treating depression | |
EP4299595A3 (en) | Compositions and methods related to engineered fc constructs | |
MX2016016881A (es) | Anticuerpos que se unen a axl. | |
PH12019500929A1 (en) | Anti il-33 antibodies and uses thereof | |
MX2017016169A (es) | Anticuerpos anti-her2 y metodos de uso. | |
EA201691470A1 (ru) | Белки, связывающие калликреин плазмы, и их применение для лечения наследственного ангионевротического отека | |
MX2020010951A (es) | Anticuerpos anti-hla-g y utilizacion de los mismos. | |
PH12016501366A1 (en) | Novel anti-baff antibodies | |
PH12018502137A1 (en) | Anti-complement factor bb antibodies and uses thereof | |
MX2018000715A (es) | Metodos para tratar cancer usando apilimod. |