MX2017012437A - Composiciones y metodos para detectar un contaminante biologico. - Google Patents

Composiciones y metodos para detectar un contaminante biologico.

Info

Publication number
MX2017012437A
MX2017012437A MX2017012437A MX2017012437A MX2017012437A MX 2017012437 A MX2017012437 A MX 2017012437A MX 2017012437 A MX2017012437 A MX 2017012437A MX 2017012437 A MX2017012437 A MX 2017012437A MX 2017012437 A MX2017012437 A MX 2017012437A
Authority
MX
Mexico
Prior art keywords
compositions
methods
detecting
biological contaminant
rapid
Prior art date
Application number
MX2017012437A
Other languages
English (en)
Inventor
Monpoeho Serge
Mink Sheldon
Vescio Paul
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56297073&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2017012437(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of MX2017012437A publication Critical patent/MX2017012437A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

En la presente, se proporcionan composiciones y métodos útiles para determinar si un contaminante microbiano está presente en un proceso de producción terapéutico biológico. Específicamente, se proporcionan un plásmido de control de amplificación positivo artificial y una sonda para detección de PCR cuantitativa única, lo cual permite una detección rápida y en tiempo real de un resultado falso positivo.
MX2017012437A 2015-03-27 2016-03-25 Composiciones y metodos para detectar un contaminante biologico. MX2017012437A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562139321P 2015-03-27 2015-03-27
PCT/US2016/024216 WO2016160572A1 (en) 2015-03-27 2016-03-25 Compositions and methods for detecting a biological contaminant

Publications (1)

Publication Number Publication Date
MX2017012437A true MX2017012437A (es) 2018-06-19

Family

ID=56297073

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017012437A MX2017012437A (es) 2015-03-27 2016-03-25 Composiciones y metodos para detectar un contaminante biologico.
MX2021007667A MX2021007667A (es) 2015-03-27 2017-09-27 Composiciones y metodos para detectar un contaminante biologico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021007667A MX2021007667A (es) 2015-03-27 2017-09-27 Composiciones y metodos para detectar un contaminante biologico.

Country Status (20)

Country Link
US (3) US10669594B2 (es)
EP (3) EP3274469B1 (es)
JP (4) JP6670847B2 (es)
KR (2) KR20240063188A (es)
CN (2) CN114875175A (es)
AR (2) AR104110A1 (es)
AU (2) AU2016243498B2 (es)
BR (1) BR112017020582A2 (es)
CA (2) CA2980915C (es)
DK (1) DK3274469T3 (es)
EA (2) EA037740B1 (es)
ES (1) ES2804845T3 (es)
IL (4) IL302434A (es)
MX (2) MX2017012437A (es)
PL (1) PL3274469T3 (es)
PT (1) PT3274469T (es)
SG (2) SG10202006108RA (es)
TW (3) TWI735433B (es)
WO (1) WO2016160572A1 (es)
ZA (2) ZA201706797B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI735433B (zh) 2015-03-27 2021-08-11 美商再生元醫藥公司 偵測生物污染物之組成物及方法
EP3638697A4 (en) 2017-06-12 2021-07-07 Bluefin Biomedicine, Inc. ANTI-IL1RAP ANTIBODIES AND ANTIBODY INGREDIENT CONJUGATES
US20190093149A1 (en) * 2017-09-27 2019-03-28 The United States Of America, As Represented By The Secretary Of Agriculture Assays for detecting multiple tick-borne pathogens
US20230159998A1 (en) * 2018-01-30 2023-05-25 Biofire Defense, Llc Methods and systems for validation of a nucleic acid amplification assay
JP2021518145A (ja) * 2018-03-20 2021-08-02 ルマサイト リミティド ライアビリティ カンパニー レーザー力細胞学を利用した高度な生物物理的および生化学的細胞モニタリングおよび定量化
WO2019226648A1 (en) 2018-05-21 2019-11-28 Battelle Memorial Institute Methods and control compositions for sequencing and chemical analyses
US11441176B2 (en) 2018-12-13 2022-09-13 Battelle Memorial Institute Methods and control compositions for a quantitative polymerase chain reaction
KR102278112B1 (ko) * 2020-07-10 2021-07-15 (주)하임바이오텍 특정 인공 뉴클레오타이드 서열을 이용한 위양성 판단용 조성물 및 이를 이용한 위양성 판단 방법
KR102532614B1 (ko) * 2020-09-18 2023-05-16 한국식품연구원 가공식품 및 농산물의 설치류 오염여부를 판별하는 방법
EP4263864A1 (en) * 2020-12-17 2023-10-25 Amgen Inc. Real time pcr method to detect bovine parvovirus 3
KR20230011040A (ko) * 2021-07-13 2023-01-20 재단법인 바이오나노헬스가드연구단 미생물 현장 오염 검출용 조성물 및 이의 용도
CN114561492A (zh) * 2022-02-28 2022-05-31 宁夏回族自治区疾病预防控制中心(宁夏回族自治区性病艾滋病防治中心) 一种新冠病毒核酸检测阳性质控品及其制备方法和用途
CN116814848B (zh) * 2023-04-12 2024-03-19 中国医学科学院医学实验动物研究所 基于荧光raa检测小鼠微小病毒的引物和探针及方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5585254A (en) * 1987-08-21 1996-12-17 University Of Colorado Foundation, Inc. Autonomous parvovirus gene delivery vehicles and expression vectors
US5371241A (en) 1991-07-19 1994-12-06 Pharmacia P-L Biochemicals Inc. Fluorescein labelled phosphoramidites
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
ATE462791T1 (de) * 1999-08-13 2010-04-15 Deutsches Krebsforsch Parvovirus ns1 varianten
AT409383B (de) * 1999-12-22 2002-07-25 Baxter Ag Verfahren zur detektion und quantifizierung von nukleinsäuren in einer probe
AU2001283278A1 (en) * 2000-08-10 2002-02-25 Neurologix, Inc. Replication competent aav helper functions
CZ308201B6 (cs) * 2001-06-28 2020-02-26 Grifols Worldwide Operations Limited Diagnostické zkoušky pro parvovirus B19
SG106672A1 (en) 2002-03-08 2004-10-29 Asml Netherlands Bv Mask for use in lithography, method of making a mask, lithographic apparatus, and device manufacturing method
CA2506574A1 (en) 2002-11-12 2004-05-27 Genolife One step real-time rt pcr kits for the universal detection of organisms in industrial products
EP1625232B1 (en) * 2003-05-16 2013-09-04 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Internal control nucleic acid molecule for nucleic acid amplification systems
DE102006034844B3 (de) 2006-07-27 2007-12-06 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Zusammensetzungen und Verfahren zur Amplifikation von Hepatitis A-Viren (HAV) und/oder Parvoviren B19 (PB19) mittels Multiplex-PCR
US7771997B2 (en) 2007-06-04 2010-08-10 Regeneron Pharmaceuticals, Inc. Enhanced expression and stability regions
EP2098599A1 (en) 2008-03-05 2009-09-09 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Composition comprising an oligonucleotide mixture for the detection of contaminations in cell cultures
US9834815B2 (en) * 2009-03-25 2017-12-05 Life Technologies Corporation Discriminatory positive/extraction control DNA
TWI507525B (zh) 2009-06-26 2015-11-11 Regeneron Pharma 具天然免疫球蛋白形式之易分離的雙專一性抗體
EP2629783B1 (en) * 2010-10-21 2014-12-17 Deutsches Krebsforschungszentrum Retargeting of rat parvovirus h-1pv to cancer cells through genetic engineering of its capsid
AU2012221740B2 (en) * 2011-02-25 2016-11-17 Novartis Ag Exogenous internal positive control
CN102206713B (zh) * 2011-04-06 2013-01-02 浙江大学 三重荧光定量rt-pcr检测试剂盒及用途
GB201203568D0 (en) * 2012-02-29 2012-04-11 Vela Operations Pte Ltd Real time PCR detection of streptococcus
HU230463B1 (hu) * 2012-07-02 2016-07-28 Ud-Genomed Medical Genomic Technologies Kft. Kontroll rendszer immunprecipitációs vizsgálatokhoz
SI2906235T1 (sl) * 2012-10-02 2017-12-29 Proclara Biosciences, Inc. Uporaba P3 bakteriofagnih fuzijskih proteinov kot amiloidnih vezavnih sredstev
GB2525024A (en) * 2014-04-10 2015-10-14 Vela Operations Pte Ltd Universal controls for sequencing assays
TWI735433B (zh) 2015-03-27 2021-08-11 美商再生元醫藥公司 偵測生物污染物之組成物及方法

Also Published As

Publication number Publication date
US20230295747A1 (en) 2023-09-21
JP7385623B2 (ja) 2023-11-22
CA2980915C (en) 2024-02-27
CA3226784A1 (en) 2016-10-06
TWI804917B (zh) 2023-06-11
US11549154B2 (en) 2023-01-10
ZA201806101B (en) 2020-12-23
EA201792155A1 (ru) 2018-04-30
TW202140801A (zh) 2021-11-01
BR112017020582A2 (pt) 2018-07-17
EA037740B1 (ru) 2021-05-17
SG10202006108RA (en) 2020-08-28
TWI735433B (zh) 2021-08-11
MX2021007667A (es) 2021-08-05
JP6670847B2 (ja) 2020-03-25
ES2804845T3 (es) 2021-02-09
US20200248278A1 (en) 2020-08-06
US20160281182A1 (en) 2016-09-29
KR20180026661A (ko) 2018-03-13
SG11201707690QA (en) 2017-10-30
JP2020103306A (ja) 2020-07-09
AU2022246398A1 (en) 2022-11-03
IL289447A (en) 2022-02-01
TW202336236A (zh) 2023-09-16
CN114875175A (zh) 2022-08-09
JP2018509174A (ja) 2018-04-05
CN107960108B (zh) 2022-03-08
IL281579B (en) 2022-02-01
WO2016160572A1 (en) 2016-10-06
AU2016243498B2 (en) 2022-07-07
US10669594B2 (en) 2020-06-02
AR119878A2 (es) 2022-01-19
AU2016243498A2 (en) 2018-04-19
EP3699298B1 (en) 2024-04-24
EP4361290A2 (en) 2024-05-01
IL254731A0 (en) 2017-11-30
EP3274469A1 (en) 2018-01-31
TW201706413A (zh) 2017-02-16
KR102662675B1 (ko) 2024-05-03
IL254731B (en) 2021-04-29
AU2016243498A1 (en) 2017-10-26
KR20240063188A (ko) 2024-05-09
EP3274469B1 (en) 2020-04-29
PL3274469T3 (pl) 2020-10-05
DK3274469T3 (da) 2020-06-15
ZA201706797B (en) 2020-01-29
AR104110A1 (es) 2017-06-28
EA202190319A1 (ru) 2021-09-30
JP2023184743A (ja) 2023-12-28
PT3274469T (pt) 2020-05-29
JP6894026B2 (ja) 2021-06-23
CN107960108A (zh) 2018-04-24
JP2021121226A (ja) 2021-08-26
IL281579A (en) 2021-05-31
IL302434A (en) 2023-06-01
CA2980915A1 (en) 2016-10-06
EP3699298A1 (en) 2020-08-26

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