MX2017009336A - Polinucleótidos dirigidos al sistema nervioso central. - Google Patents
Polinucleótidos dirigidos al sistema nervioso central.Info
- Publication number
- MX2017009336A MX2017009336A MX2017009336A MX2017009336A MX2017009336A MX 2017009336 A MX2017009336 A MX 2017009336A MX 2017009336 A MX2017009336 A MX 2017009336A MX 2017009336 A MX2017009336 A MX 2017009336A MX 2017009336 A MX2017009336 A MX 2017009336A
- Authority
- MX
- Mexico
- Prior art keywords
- nervous system
- central nervous
- targeting polynucleotides
- system targeting
- polynucleotides
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0083—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the administration regime
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención se relaciona con composiciones y métodos para la preparación, fabricación y uso terapéutico de polinucleótidos que codifican cargas para el tratamiento de trastornos del SNC.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562104101P | 2015-01-16 | 2015-01-16 | |
US201562152185P | 2015-04-24 | 2015-04-24 | |
US201562152283P | 2015-04-24 | 2015-04-24 | |
US201562159888P | 2015-05-11 | 2015-05-11 | |
US201562159882P | 2015-05-11 | 2015-05-11 | |
PCT/US2016/013671 WO2016115503A1 (en) | 2015-01-16 | 2016-01-15 | Central nervous system targeting polynucleotides |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017009336A true MX2017009336A (es) | 2017-11-15 |
Family
ID=56406481
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017009336A MX2017009336A (es) | 2015-01-16 | 2016-01-15 | Polinucleótidos dirigidos al sistema nervioso central. |
MX2022003323A MX2022003323A (es) | 2015-01-16 | 2017-07-17 | Polinucleotidos dirigidos al sistema nervioso central. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022003323A MX2022003323A (es) | 2015-01-16 | 2017-07-17 | Polinucleotidos dirigidos al sistema nervioso central. |
Country Status (7)
Country | Link |
---|---|
US (2) | US20180021364A1 (es) |
EP (2) | EP3632923A1 (es) |
AU (2) | AU2016206478A1 (es) |
CA (1) | CA2970730A1 (es) |
HK (1) | HK1246815A1 (es) |
MX (2) | MX2017009336A (es) |
WO (1) | WO2016115503A1 (es) |
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WO2016172659A1 (en) * | 2015-04-24 | 2016-10-27 | University Of Florida Research Foundation, Inc. | Aav vector for treatment of friedreich's ataxia |
CA3002406A1 (en) * | 2015-10-29 | 2017-05-04 | Voyager Therapeutics, Inc. | Delivery of central nervous system targeting polynucleotides |
LT3411484T (lt) * | 2016-02-05 | 2023-11-27 | Emory University | Viengrandžio arba sau pačiam komplementaraus adeno-asocijuoto viruso 9 injekcija į smegenų skystį |
IL302748A (en) | 2016-05-18 | 2023-07-01 | Voyager Therapeutics Inc | modulatory polynucleotides |
CN109831916B (zh) | 2016-05-18 | 2023-07-21 | 沃雅戈治疗公司 | 治疗亨廷顿氏舞蹈病的组合物和方法 |
MX2019005235A (es) * | 2016-11-09 | 2019-12-05 | Intrexon Corp | Constructos de expresion de frataxina. |
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WO2020069461A1 (en) * | 2018-09-28 | 2020-04-02 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
WO2020106916A1 (en) * | 2018-11-21 | 2020-05-28 | Stridebio, Inc. | Recombinant viral vectors and nucleic acids for producing the same |
TW202102525A (zh) | 2019-03-21 | 2021-01-16 | 美商史崔德生物公司 | 重組腺相關病毒載體 |
MX2021013266A (es) * | 2019-04-29 | 2021-11-17 | Univ Pennsylvania | Nuevas capsides de aav y composiciones que las contienen. |
MX2021015076A (es) * | 2019-06-10 | 2022-06-02 | Homology Medicines Inc | Composiciones de virus adeno-asociados para transferencia del gen de la enzima lisosomal arilsulfatasa-a (arsa) y metodos de uso de las mismas. |
EP4028027A4 (en) * | 2019-09-13 | 2023-11-01 | Lacerta Therapeutics, Inc | COMPOSITIONS AND METHODS FOR TREATING FRIEDREICH AAXIA |
GB201913974D0 (en) * | 2019-09-27 | 2019-11-13 | King S College London | Vector |
TW202128736A (zh) | 2019-10-17 | 2021-08-01 | 美商史崔德生物公司 | 用於治療c型尼曼—匹克病之腺相關病毒載體 |
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-
2016
- 2016-01-15 EP EP19209982.8A patent/EP3632923A1/en active Pending
- 2016-01-15 US US15/543,773 patent/US20180021364A1/en not_active Abandoned
- 2016-01-15 AU AU2016206478A patent/AU2016206478A1/en not_active Abandoned
- 2016-01-15 MX MX2017009336A patent/MX2017009336A/es unknown
- 2016-01-15 WO PCT/US2016/013671 patent/WO2016115503A1/en active Application Filing
- 2016-01-15 CA CA2970730A patent/CA2970730A1/en not_active Abandoned
- 2016-01-15 EP EP16737993.2A patent/EP3245221A4/en not_active Withdrawn
-
2017
- 2017-07-17 MX MX2022003323A patent/MX2022003323A/es unknown
-
2018
- 2018-05-18 HK HK18106524.2A patent/HK1246815A1/zh unknown
-
2019
- 2019-06-14 US US16/442,003 patent/US20190365793A1/en not_active Abandoned
-
2021
- 2021-07-01 AU AU2021204620A patent/AU2021204620A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HK1246815A1 (zh) | 2018-09-14 |
EP3632923A1 (en) | 2020-04-08 |
WO2016115503A1 (en) | 2016-07-21 |
US20190365793A1 (en) | 2019-12-05 |
AU2021204620A1 (en) | 2021-07-29 |
AU2016206478A1 (en) | 2017-06-15 |
CA2970730A1 (en) | 2016-07-21 |
EP3245221A1 (en) | 2017-11-22 |
EP3245221A4 (en) | 2018-06-13 |
US20180021364A1 (en) | 2018-01-25 |
MX2022003323A (es) | 2022-04-18 |
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