MX2017002544A - Derivados de isoquinolinona utiles en el tratamiento contra el cancer. - Google Patents

Derivados de isoquinolinona utiles en el tratamiento contra el cancer.

Info

Publication number
MX2017002544A
MX2017002544A MX2017002544A MX2017002544A MX2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A MX 2017002544 A MX2017002544 A MX 2017002544A
Authority
MX
Mexico
Prior art keywords
cancer
treatment
derivatives useful
isoquinolinone derivatives
compound
Prior art date
Application number
MX2017002544A
Other languages
English (en)
Inventor
Bachir Kaloun El
Schmitt Philippe
Kruczynski Anna
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of MX2017002544A publication Critical patent/MX2017002544A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

La presente invención se relaciona a un compuesto de la siguiente fórmula (I): (ver Fórmula) o una sal y/o solvato farmacéuticamente aceptables, del mismo, en particular para su uso como un fármaco, sobre todo para el tratamiento contra el cáncer, así como a composiciones farmacéuticas que contienen tal compuesto y a procesos para preparar tal compuesto.
MX2017002544A 2014-09-02 2015-09-02 Derivados de isoquinolinona utiles en el tratamiento contra el cancer. MX2017002544A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14306352 2014-09-02
PCT/EP2015/070082 WO2016034642A1 (en) 2014-09-02 2015-09-02 Isoquinolinone derivatives useful in the treatment of cancer

Publications (1)

Publication Number Publication Date
MX2017002544A true MX2017002544A (es) 2017-07-19

Family

ID=51494243

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017002544A MX2017002544A (es) 2014-09-02 2015-09-02 Derivados de isoquinolinona utiles en el tratamiento contra el cancer.

Country Status (8)

Country Link
US (1) US9944641B2 (es)
EP (1) EP3189051A1 (es)
JP (1) JP2017525734A (es)
CN (1) CN106795154B (es)
BR (1) BR112017003651A2 (es)
MX (1) MX2017002544A (es)
RU (1) RU2690853C2 (es)
WO (1) WO2016034642A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3030283A1 (en) * 2016-07-08 2018-01-11 Rigel Pharmaceuticals, Inc. Tyrosine kinase inhibitors
CN106699608A (zh) * 2016-12-26 2017-05-24 常州大学 一种含有强吸电子基团的苯胍及其盐的制备方法
US11666888B2 (en) 2018-02-05 2023-06-06 Bio-Rad Laboratories, Inc. Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2783B1 (en) * 2005-09-30 2014-03-15 نوفارتيس ايه جي Compounds 2-Amino-7, 8-dihydro-6H-Bayredo (3,4-D) Pyrimidine-5-Ones
EP2100894A1 (en) * 2008-03-12 2009-09-16 4Sc Ag Pyridopyrimidines used as Plk1 (polo-like kinase) inhibitors
AU2012209373A1 (en) 2011-01-24 2013-04-11 Glaxosmithkline Llc Isoquinoline compounds and methods for treating HIV
CA2845409A1 (en) * 2011-09-20 2013-03-28 Yingjie Lai Imidazopyridine compounds, compositions and methods of use
WO2013110585A1 (en) * 2012-01-23 2013-08-01 Boehringer Ingelheim International Gmbh 5, 8 -dihydro- 6h- pyrazolo [3, 4 -h] quinazolines as igf-lr/lr inhibitors
MX2014010176A (es) * 2012-02-23 2014-11-10 Abbvie Inc Inhibidores de cinasas de piridopirimidinona.
EP3388436B1 (en) * 2013-03-15 2020-08-12 Dana-Farber Cancer Institute, Inc. Pyrimido-diazepinone compounds and methods of treating disorders

Also Published As

Publication number Publication date
US9944641B2 (en) 2018-04-17
BR112017003651A2 (pt) 2017-12-05
RU2017108909A (ru) 2018-10-03
EP3189051A1 (en) 2017-07-12
RU2017108909A3 (es) 2018-12-13
WO2016034642A1 (en) 2016-03-10
CN106795154A (zh) 2017-05-31
RU2690853C2 (ru) 2019-06-06
US20170240544A1 (en) 2017-08-24
JP2017525734A (ja) 2017-09-07
CN106795154B (zh) 2019-07-05

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