MX2016013999A - Conjugado farmaco-anticuerpo y su uso para el tratamiento contra el cancer. - Google Patents

Conjugado farmaco-anticuerpo y su uso para el tratamiento contra el cancer.

Info

Publication number
MX2016013999A
MX2016013999A MX2016013999A MX2016013999A MX2016013999A MX 2016013999 A MX2016013999 A MX 2016013999A MX 2016013999 A MX2016013999 A MX 2016013999A MX 2016013999 A MX2016013999 A MX 2016013999A MX 2016013999 A MX2016013999 A MX 2016013999A
Authority
MX
Mexico
Prior art keywords
antibody
drug
conjugate
treatment
cancer
Prior art date
Application number
MX2016013999A
Other languages
English (en)
Inventor
Goetsch Liliane
Beau-Larvor Charlotte
Perez Michel
Rilatt Ian
Broussas Matthieu
Francois HAEUW Jean-
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of MX2016013999A publication Critical patent/MX2016013999A/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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Abstract

La presente invención se relaciona con un conjugado fármaco-anticuerpo. Considerando un aspecto, la invención se relaciona con un conjugado fármaco-anticuerpo que comprende un anticuerpo capaz unirse a un Objetivo, el anticuerpo se conjuga con al menos un fármaco seleccionado a partir de derivados de dolastatina 10 y auristatinas. La invención también comprende un método de tratamiento y el uso de dicho conjugado fármaco-anticuerpo para el tratamiento contra el cáncer.
MX2016013999A 2014-04-25 2015-04-27 Conjugado farmaco-anticuerpo y su uso para el tratamiento contra el cancer. MX2016013999A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14305621 2014-04-25
PCT/EP2015/059052 WO2015162293A1 (en) 2014-04-25 2015-04-27 Antibody-drug-conjugate and its use for the treatment of cancer

Publications (1)

Publication Number Publication Date
MX2016013999A true MX2016013999A (es) 2017-05-30

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MX2016013999A MX2016013999A (es) 2014-04-25 2015-04-27 Conjugado farmaco-anticuerpo y su uso para el tratamiento contra el cancer.

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