MX2016005273A - Procedimiento y sistema de deteccion. - Google Patents

Procedimiento y sistema de deteccion.

Info

Publication number
MX2016005273A
MX2016005273A MX2016005273A MX2016005273A MX2016005273A MX 2016005273 A MX2016005273 A MX 2016005273A MX 2016005273 A MX2016005273 A MX 2016005273A MX 2016005273 A MX2016005273 A MX 2016005273A MX 2016005273 A MX2016005273 A MX 2016005273A
Authority
MX
Mexico
Prior art keywords
sensing
compartment
disclosed
methods
systems
Prior art date
Application number
MX2016005273A
Other languages
English (en)
Inventor
Fernando Patolsky
Chang Hsiung Le-
Krivitsky Vadim
Naddaka Vladimir
Original Assignee
Ramot At Tel-Aviv Univ Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ramot At Tel-Aviv Univ Ltd filed Critical Ramot At Tel-Aviv Univ Ltd
Publication of MX2016005273A publication Critical patent/MX2016005273A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7057—(Intracellular) signaling and trafficking pathways
    • G01N2800/7066—Metabolic pathways

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Electrochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)

Abstract

Se divulgas sistemas y procedimientos para detectar molécula dianas tales como agentes reactivos rédox, que comprenden un compartimento de muestra y un compartimento de detección que están en comunicación de fluidos. Un compartimento de detección que comprende nanoestructuras a las que se ha unido covalentemente un resto funcional y que es de tal manera que, después de entrar en contacto con un agente reactivo rédox, se produce un cambio en una propiedad eléctrica de la nanoestructura, también se describe la integración de dicho compartimento de detección con sistemas detectores tal como se describe en el presente documento. También se describen procedimientos para vigilar una actividad metabólica de células, y usos de los mismos.
MX2016005273A 2013-10-22 2014-10-22 Procedimiento y sistema de deteccion. MX2016005273A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361893977P 2013-10-22 2013-10-22
PCT/IL2014/050921 WO2015059704A1 (en) 2013-10-22 2014-10-22 Method and system for sensing

Publications (1)

Publication Number Publication Date
MX2016005273A true MX2016005273A (es) 2017-01-05

Family

ID=51894171

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005273A MX2016005273A (es) 2013-10-22 2014-10-22 Procedimiento y sistema de deteccion.

Country Status (11)

Country Link
US (2) US10274456B2 (es)
EP (1) EP3060675B1 (es)
JP (1) JP6609247B2 (es)
KR (1) KR20160072258A (es)
CN (1) CN106164286A (es)
AU (1) AU2014338510A1 (es)
CA (1) CA2927332A1 (es)
HK (1) HK1225414B (es)
MX (1) MX2016005273A (es)
SG (1) SG11201602976XA (es)
WO (1) WO2015059704A1 (es)

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* Cited by examiner, † Cited by third party
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KR20160072258A (ko) 2013-10-22 2016-06-22 라모트 앳 텔-아비브 유니버시티 리미티드 감지를 위한 방법 및 시스템
CN106999929A (zh) * 2014-09-11 2017-08-01 克忧公司 用于检测和量化分析物的***和方法
KR20180091053A (ko) 2015-12-09 2018-08-14 라모트 앳 텔-아비브 유니버시티 리미티드 변형된 나노구조에 의한 감지 방법 및 시스템
US10940474B2 (en) * 2016-03-21 2021-03-09 University Of South Australia Oxidant sensor
AU2017276539B2 (en) * 2016-06-10 2019-06-27 Unilever Global Ip Limited A machine comprising a device for controlling the machine or process by detecting a quality of a fluid formulation to be introduced in the machine and corresponding methods
WO2018037407A1 (en) * 2016-08-22 2018-03-01 Ramot At Tel-Aviv University Ltd. Method and system for subcutaneous sensing
WO2018037406A1 (en) 2016-08-22 2018-03-01 Ramot At Tel-Aviv University Ltd. Methods and systems for detecting bioanalytes
US11193888B2 (en) 2017-03-29 2021-12-07 Ramot At Tel-Aviv University Ltd. Method and system for separating biomolecules from a mixture containing same
WO2018198008A1 (en) * 2017-04-24 2018-11-01 Abdolahad Mohammad In-situ microbubbles generation for ultrasonic biomedical applications
IL260057B (en) 2017-06-15 2020-04-30 Filanovsky Boris Electrochemical detection of nitro-containing compounds
SG11201911854RA (en) 2017-06-15 2020-01-30 Univ Ramot Electrochemical detection of peroxide-containing compounds
US11179077B2 (en) 2017-06-20 2021-11-23 Mohammad Abdolahad Apparatus for in-vivo measuring of H2O2 oxidation
US10786188B1 (en) * 2017-06-20 2020-09-29 Mohammad Abdolahad Real-time and label free analyzer for in-vitro and in-vivo detection of cancer
CN111225604A (zh) * 2017-06-20 2020-06-02 ***.阿波拉哈德 用于对癌症可疑区域进行体外和体内检测的实时无标记分析仪
SG11201912263VA (en) * 2017-08-01 2020-01-30 Illumina Inc Field effect sensors
WO2019038761A1 (en) * 2017-08-21 2019-02-28 Savicell Diagnostic Ltd. METHODS FOR THE DIAGNOSIS AND TREATMENT OF LUNG CANCER
TWI765209B (zh) * 2019-01-18 2022-05-21 國立陽明交通大學 用來偵測全細胞細菌之以場效電晶體為主的生物感測器以及包含生物感測器的生物感測器組
CN114364976A (zh) 2019-07-12 2022-04-15 曲莱博医疗有限公司 电化学fet传感器
CN111487107B (zh) * 2020-06-07 2022-12-09 黑龙江省农业科学院农产品质量安全研究所 一种用于食品安全检测的样本分级处理装置

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KR20180091053A (ko) 2015-12-09 2018-08-14 라모트 앳 텔-아비브 유니버시티 리미티드 변형된 나노구조에 의한 감지 방법 및 시스템

Also Published As

Publication number Publication date
US10274456B2 (en) 2019-04-30
JP2016535988A (ja) 2016-11-24
KR20160072258A (ko) 2016-06-22
AU2014338510A1 (en) 2016-06-09
EP3060675A1 (en) 2016-08-31
CA2927332A1 (en) 2015-04-30
HK1225414B (zh) 2017-09-08
US20160258899A1 (en) 2016-09-08
US20190234900A1 (en) 2019-08-01
EP3060675B1 (en) 2019-01-30
CN106164286A (zh) 2016-11-23
SG11201602976XA (en) 2016-05-30
WO2015059704A1 (en) 2015-04-30
JP6609247B2 (ja) 2019-11-20

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