MX2015016678A - Formulaciones farmaceuticas que comprenden agomelatina en forma de cocristal de agomelatina con un acido organico. - Google Patents
Formulaciones farmaceuticas que comprenden agomelatina en forma de cocristal de agomelatina con un acido organico.Info
- Publication number
- MX2015016678A MX2015016678A MX2015016678A MX2015016678A MX2015016678A MX 2015016678 A MX2015016678 A MX 2015016678A MX 2015016678 A MX2015016678 A MX 2015016678A MX 2015016678 A MX2015016678 A MX 2015016678A MX 2015016678 A MX2015016678 A MX 2015016678A
- Authority
- MX
- Mexico
- Prior art keywords
- agomelatine
- crystal
- organic acid
- pharmaceutical formulations
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/145—Maleic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/265—Citric acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Una formulación farmacéutica que comprende agomelatina en forma de cocristal de agomelatina con un formador de cocristales seleccionado del grupo de ácidos orgánicos en una cantidad correspondiente a una dosis de 15-22 mg de agomelatina por una unidad de dosificación y al menos un excipiente farmacéuticamente aceptable para el tratamiento eficaz de enfermedades que responden a la terapia con agomelatina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13002931.7A EP2810647A1 (en) | 2013-06-06 | 2013-06-06 | Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid |
PCT/EP2014/001409 WO2014194991A1 (en) | 2013-06-06 | 2014-05-24 | Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015016678A true MX2015016678A (es) | 2016-08-08 |
Family
ID=48606993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015016678A MX2015016678A (es) | 2013-06-06 | 2014-05-24 | Formulaciones farmaceuticas que comprenden agomelatina en forma de cocristal de agomelatina con un acido organico. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2810647A1 (es) |
JP (1) | JP2016520628A (es) |
KR (1) | KR20160014618A (es) |
CN (1) | CN105407882A (es) |
BR (1) | BR112015030388A2 (es) |
EA (1) | EA201592261A1 (es) |
MX (1) | MX2015016678A (es) |
WO (1) | WO2014194991A1 (es) |
ZA (1) | ZA201508860B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3466413A1 (en) | 2017-10-09 | 2019-04-10 | KRKA, d.d., Novo mesto | Pharmaceutical composition containing agomelatine and process for the preparation thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2658818B1 (fr) | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2795326B1 (fr) | 1999-06-28 | 2001-08-31 | Adir | Composition pharmaceutique solide thermoformable a liberation controlee |
FR2834890B1 (fr) | 2002-01-23 | 2004-02-27 | Servier Lab | Composition pharmaceutique orodispersible d'agomelatine |
FR2866335B1 (fr) | 2004-02-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
FR2889521B1 (fr) | 2005-08-03 | 2007-12-28 | Servier Lab | Nouvelle forme cristalline iii de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2889522B1 (fr) | 2005-08-03 | 2007-12-28 | Servier Lab | Nouvelle forme cristalline iv de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2889523B1 (fr) | 2005-08-03 | 2007-12-28 | Servier Lab | Nouvelle forme cristalline v de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2890562B1 (fr) | 2005-09-09 | 2012-10-12 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles du sommeil chez le patient deprime |
FR2894475B1 (fr) | 2005-12-14 | 2008-05-16 | Servier Lab | Composition pharmaceutique orodispersible pour administra- -tion oromucosale ou sublinguale d'agomelatine |
FR2899472B1 (fr) | 2006-04-07 | 2008-09-12 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee |
FR2908995B1 (fr) * | 2006-11-24 | 2009-02-06 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du syndrome de smith magenis |
FR2908994B1 (fr) * | 2006-11-24 | 2009-04-03 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement de la leucomalacie periventriculaire |
FR2923482B1 (fr) | 2007-11-09 | 2010-01-29 | Servier Lab | Nouvelle forme cristalline vi de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
CN102106807B (zh) | 2009-12-29 | 2013-03-27 | 上海中西制药有限公司 | 一种固体制剂的制备方法及所得固体制剂 |
CN101991559B (zh) | 2010-11-25 | 2012-04-18 | 天津市汉康医药生物技术有限公司 | 一种稳定的阿戈美拉汀胶囊药物组合物 |
EP2517700B1 (en) * | 2011-04-28 | 2013-07-17 | Zentiva, k.s. | Pharmaceutically acceptable cocrystals of N-[2-(7-methoxy-1-naphthyl]acetamide and methods of their preparation |
PH12012000132B1 (en) | 2011-06-09 | 2014-10-20 | Servier Lab | New co-crystals of agomelatine, a process for their preparation and pharmaceutical compositions containing them |
FR2976284B1 (fr) * | 2011-06-09 | 2013-05-24 | Servier Lab | Nouveaux co-cristaux d'agomelatine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
EP2551257A1 (en) * | 2011-07-28 | 2013-01-30 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of agomelatine with co-crystal-formers |
-
2013
- 2013-06-06 EP EP13002931.7A patent/EP2810647A1/en not_active Withdrawn
-
2014
- 2014-05-24 WO PCT/EP2014/001409 patent/WO2014194991A1/en active Application Filing
- 2014-05-24 CN CN201480040196.5A patent/CN105407882A/zh active Pending
- 2014-05-24 MX MX2015016678A patent/MX2015016678A/es unknown
- 2014-05-24 KR KR1020157033931A patent/KR20160014618A/ko not_active Application Discontinuation
- 2014-05-24 EA EA201592261A patent/EA201592261A1/ru unknown
- 2014-05-24 JP JP2016517183A patent/JP2016520628A/ja active Pending
- 2014-05-24 BR BR112015030388A patent/BR112015030388A2/pt not_active IP Right Cessation
-
2015
- 2015-12-03 ZA ZA2015/08860A patent/ZA201508860B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN105407882A (zh) | 2016-03-16 |
BR112015030388A2 (pt) | 2017-07-25 |
JP2016520628A (ja) | 2016-07-14 |
EP2810647A1 (en) | 2014-12-10 |
WO2014194991A1 (en) | 2014-12-11 |
KR20160014618A (ko) | 2016-02-11 |
EA201592261A1 (ru) | 2016-05-31 |
ZA201508860B (en) | 2017-08-30 |
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