MX2015000740A - Composicion de liposomas para usarse en dialisis peritoneal. - Google Patents
Composicion de liposomas para usarse en dialisis peritoneal.Info
- Publication number
- MX2015000740A MX2015000740A MX2015000740A MX2015000740A MX2015000740A MX 2015000740 A MX2015000740 A MX 2015000740A MX 2015000740 A MX2015000740 A MX 2015000740A MX 2015000740 A MX2015000740 A MX 2015000740A MX 2015000740 A MX2015000740 A MX 2015000740A
- Authority
- MX
- Mexico
- Prior art keywords
- liposome
- liposomes
- present
- toxicopathies
- peritoneal dialysis
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 6
- 238000000502 dialysis Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000003053 toxin Substances 0.000 abstract 2
- 231100000765 toxin Toxicity 0.000 abstract 2
- 206010020575 Hyperammonaemia Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 238000007912 intraperitoneal administration Methods 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/287—Dialysates therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención está dirigida a una composición de liposomas para usarse en la diálisis peritoneal de pacientes que padecen de toxicopatías endógenas o exógenas, en donde el pH dentro los liposomas difiere del pH en la cavidad peritoneal y en donde el pH dentro del liposoma conduce a una toxina cargada encapsulada en el liposoma. La invención también se refiere a una composición farmacéutica que comprende los liposomas. Un aspecto adicional de la presente invención se refiere a un método de tratamiento de los pacientes que sufren de toxicopatías endógenas o exógenas, seleccionadas preferentemente de toxicopatías por fármacos, metabolitos, pesticidas, insecticidas, toxinas, y por guerra química, más preferentemente hiperamonemia, que comprende la etapa de administrar los liposomas de la invención en una cantidad efectiva terapéuticamente en el espacio peritoneal de un paciente que tenga la necesidad de los mismos. Después de los seres humanos, la presente invención es particularmente adecuada para los aspectos veterinarios.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12005796.3A EP2695606A1 (en) | 2012-08-09 | 2012-08-09 | Liposome composition for peritoneal dialysis |
| PCT/EP2013/002352 WO2014023421A1 (en) | 2012-08-09 | 2013-08-06 | Liposome composition for use in peritoneal dialysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015000740A true MX2015000740A (es) | 2015-04-14 |
| MX362882B MX362882B (es) | 2019-02-22 |
Family
ID=47022433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015000740A MX362882B (es) | 2012-08-09 | 2013-08-06 | Composición de liposomas para usarse en diálisis peritoneal. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10596114B2 (es) |
| EP (3) | EP2695606A1 (es) |
| JP (1) | JP5956075B2 (es) |
| KR (2) | KR101966308B1 (es) |
| CN (2) | CN110269841A (es) |
| AU (1) | AU2013301901B9 (es) |
| BR (2) | BR112015002584B1 (es) |
| CA (1) | CA2894784C (es) |
| DK (1) | DK2882421T3 (es) |
| ES (1) | ES2922278T3 (es) |
| HK (1) | HK1209059A1 (es) |
| MX (1) | MX362882B (es) |
| PT (1) | PT2882421T (es) |
| RU (1) | RU2609860C2 (es) |
| WO (1) | WO2014023421A1 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2695606A1 (en) * | 2012-08-09 | 2014-02-12 | ETH Zürich | Liposome composition for peritoneal dialysis |
| WO2016048242A1 (en) * | 2014-09-24 | 2016-03-31 | Nanyang Technological University | Sustained timolol maleate delivery from liposomes for glaucoma therapy and ocular hypertension |
| WO2016159879A1 (en) * | 2015-04-02 | 2016-10-06 | Nanyang Technological University | Tubular and vesicular architectures formed from polymer-lipid blends and method for forming the same |
| JP6715265B2 (ja) | 2015-05-04 | 2020-07-01 | フェルザンティス アーゲーＶｅｒｓａｎｔｉｓ Ａｇ | 膜内外ｐＨ勾配ベシクルを調製する方法 |
| EP3120842A1 (en) * | 2015-07-20 | 2017-01-25 | Opterion Health AG | Peritoneal therapeutic fluid |
| WO2017187426A1 (en) * | 2016-04-29 | 2017-11-02 | Aptamir Therapeutics, Inc. | Inhibition of mir-22 mirna by apt-110 |
| CN106220562B (zh) * | 2016-07-29 | 2019-10-01 | 上海璃道医药科技有限公司 | 两种喹啉环类药物的新用途 |
| WO2018033856A1 (en) * | 2016-08-16 | 2018-02-22 | Eth Zurich | Transmembrane ph-gradient polymersomes and their use in the scavenging of ammonia and its methylated analogs |
| JP7203438B2 (ja) * | 2017-09-12 | 2023-01-13 | イーティーエイチ・チューリッヒ | 体液中アンモニア定量用の膜貫通ｐＨ勾配ポリマーソーム |
| KR20190085734A (ko) | 2018-01-11 | 2019-07-19 | 이광영 | 말뚝의 결합장치 |
| US20210015844A1 (en) * | 2018-03-14 | 2021-01-21 | Beacon Medcare (Hk) Limited | Composition for purification of biofluids |
| CN111939126A (zh) * | 2019-05-15 | 2020-11-17 | 上海交通大学医学院附属第九人民医院 | 一种阳离子脂质体、包含所述脂质体的分散液及它们的制备方法和用途 |
| CN109966277B (zh) * | 2019-05-23 | 2021-04-30 | 济宁医学院附属医院 | 一种治疗难治性癫痫的药物组合物及其应用 |
| CN112294763A (zh) * | 2019-07-30 | 2021-02-02 | 上海交通大学医学院附属第九人民医院 | 一种腹膜透析用脂质体分散液及其制备方法和用途 |
| KR20210128169A (ko) | 2020-04-16 | 2021-10-26 | 이광영 | 파일 결합 장치 |
| MX2023005797A (es) | 2020-11-17 | 2023-05-29 | Genfit | Metodos de tratamiento de la insuficiencia hepatica. |
| CN112933045B (zh) * | 2021-04-09 | 2022-04-12 | 贵州医科大学 | 共载双氢青蒿素/磷酸氯喹双敏感纳米制剂及其制备方法 |
| WO2024105101A1 (en) | 2022-11-16 | 2024-05-23 | Genfit | Use of transmembrane ph gradient liposomes for treating hyperammonemic crisis associated with inborn errors of metabolism |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE446063B (sv) | 1978-02-01 | 1986-08-11 | Exxon Research Engineering Co | Vetskemembrankapsel som er motstandskrafitg mot koalescens och forfarande for framstellning av vetskemembrankapslar |
| MX9203808A (es) * | 1987-03-05 | 1992-07-01 | Liposome Co Inc | Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos. |
| US20040208922A1 (en) * | 1995-06-07 | 2004-10-21 | The Regents Of The University Of California | Method for loading lipid like vesicles with drugs or other chemicals |
| WO1997000075A1 (fr) * | 1995-06-14 | 1997-01-03 | Institute Of Immunology Co., Ltd. | Medicament contre le prurit cutane accompagnant l'insuffisance renale |
| CN1119145C (zh) * | 1995-10-11 | 2003-08-27 | 埃斯佩里安Luv发展公司 | 脂质体组合物及其使用方法 |
| CN1160585A (zh) * | 1995-12-22 | 1997-10-01 | 贝尔科公开有限公司 | 除去脂溶性靶分子的方法，纯化血液的透析装置及洗涤溶液 |
| DE10117043A1 (de) * | 2001-04-05 | 2002-11-07 | Gerhard Puetz | Verfahren zur Eliminierung von potentiell toxischen und/oder schädlichen Stoffen |
| US20030129224A1 (en) * | 2001-11-13 | 2003-07-10 | Paul Tardi | Lipid carrier compositions and methods for improved drug retention |
| WO2009114826A2 (en) * | 2008-03-13 | 2009-09-17 | Angiodynamics, Inc. | Treatment systems and methods for renal-related diseases |
| JP5450612B2 (ja) * | 2008-06-18 | 2014-03-26 | ライフボンド リミテッド | 改良された架橋組成物 |
| EP2695606A1 (en) * | 2012-08-09 | 2014-02-12 | ETH Zürich | Liposome composition for peritoneal dialysis |
-
2012
- 2012-08-09 EP EP12005796.3A patent/EP2695606A1/en not_active Withdrawn
-
2013
- 2013-08-06 CN CN201910232676.6A patent/CN110269841A/zh active Pending
- 2013-08-06 CA CA2894784A patent/CA2894784C/en active Active
- 2013-08-06 CN CN201380042294.8A patent/CN104519873A/zh active Pending
- 2013-08-06 WO PCT/EP2013/002352 patent/WO2014023421A1/en active Application Filing
- 2013-08-06 EP EP13745798.2A patent/EP2882421B1/en active Active
- 2013-08-06 EP EP22172208.5A patent/EP4062905A1/en active Pending
- 2013-08-06 AU AU2013301901A patent/AU2013301901B9/en active Active
- 2013-08-06 BR BR112015002584-6A patent/BR112015002584B1/pt active IP Right Grant
- 2013-08-06 BR BR122019024753-6A patent/BR122019024753B1/pt active IP Right Grant
- 2013-08-06 US US14/420,654 patent/US10596114B2/en active Active
- 2013-08-06 ES ES13745798T patent/ES2922278T3/es active Active
- 2013-08-06 KR KR1020157001870A patent/KR101966308B1/ko active IP Right Grant
- 2013-08-06 RU RU2014153193A patent/RU2609860C2/ru active
- 2013-08-06 MX MX2015000740A patent/MX362882B/es active IP Right Grant
- 2013-08-06 KR KR1020177022844A patent/KR101993775B1/ko active IP Right Grant
- 2013-08-06 DK DK13745798.2T patent/DK2882421T3/da active
- 2013-08-06 PT PT137457982T patent/PT2882421T/pt unknown
- 2013-08-06 JP JP2015525780A patent/JP5956075B2/ja active Active
-
2015
- 2015-10-12 HK HK15109906.7A patent/HK1209059A1/xx unknown
-
2018
- 2018-10-19 US US16/165,202 patent/US20190105270A1/en not_active Abandoned
-
2020
- 2020-09-11 US US17/018,438 patent/US11896712B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |