MX2014014162A - Anticuerpos multiespecificos. - Google Patents
Anticuerpos multiespecificos.Info
- Publication number
- MX2014014162A MX2014014162A MX2014014162A MX2014014162A MX2014014162A MX 2014014162 A MX2014014162 A MX 2014014162A MX 2014014162 A MX2014014162 A MX 2014014162A MX 2014014162 A MX2014014162 A MX 2014014162A MX 2014014162 A MX2014014162 A MX 2014014162A
- Authority
- MX
- Mexico
- Prior art keywords
- multispecific antibodies
- human
- bivalent
- antibodies
- bind
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
Abstract
La presente invención se refiere a anticuerpos multiespecíficos bivalentes, especialmente anticuerpos triespecíficos bivalentes que se unen a HER1 humano, HER2 humano y HER3 humano, a su elaboración y uso.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12169340 | 2012-05-24 | ||
PCT/EP2013/060529 WO2013174873A1 (en) | 2012-05-24 | 2013-05-22 | Multispecific antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2014014162A true MX2014014162A (es) | 2015-02-04 |
Family
ID=48470986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014014162A MX2014014162A (es) | 2012-05-24 | 2013-05-22 | Anticuerpos multiespecificos. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20150166670A1 (es) |
EP (1) | EP2855531A1 (es) |
JP (1) | JP2015520168A (es) |
KR (1) | KR20150013188A (es) |
CN (1) | CN104379604A (es) |
BR (1) | BR112014026990A2 (es) |
CA (1) | CA2869529A1 (es) |
HK (1) | HK1203517A1 (es) |
MX (1) | MX2014014162A (es) |
RU (1) | RU2014149681A (es) |
WO (1) | WO2013174873A1 (es) |
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2013
- 2013-05-22 CA CA2869529A patent/CA2869529A1/en not_active Abandoned
- 2013-05-22 CN CN201380027168.5A patent/CN104379604A/zh active Pending
- 2013-05-22 RU RU2014149681A patent/RU2014149681A/ru not_active Application Discontinuation
- 2013-05-22 WO PCT/EP2013/060529 patent/WO2013174873A1/en active Application Filing
- 2013-05-22 MX MX2014014162A patent/MX2014014162A/es unknown
- 2013-05-22 BR BR112014026990A patent/BR112014026990A2/pt not_active IP Right Cessation
- 2013-05-22 JP JP2015513157A patent/JP2015520168A/ja active Pending
- 2013-05-22 KR KR1020147032719A patent/KR20150013188A/ko not_active Application Discontinuation
- 2013-05-22 EP EP13724269.9A patent/EP2855531A1/en not_active Withdrawn
-
2014
- 2014-11-24 US US14/551,957 patent/US20150166670A1/en not_active Abandoned
-
2015
- 2015-04-20 HK HK15103796.3A patent/HK1203517A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP2855531A1 (en) | 2015-04-08 |
CN104379604A (zh) | 2015-02-25 |
HK1203517A1 (en) | 2015-10-30 |
KR20150013188A (ko) | 2015-02-04 |
US20150166670A1 (en) | 2015-06-18 |
CA2869529A1 (en) | 2013-11-28 |
BR112014026990A2 (pt) | 2017-07-11 |
WO2013174873A1 (en) | 2013-11-28 |
RU2014149681A (ru) | 2016-07-20 |
JP2015520168A (ja) | 2015-07-16 |
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