MX2013003551A - Formas en estado solido de un potente inhibidor del vch. - Google Patents

Formas en estado solido de un potente inhibidor del vch.

Info

Publication number
MX2013003551A
MX2013003551A MX2013003551A MX2013003551A MX2013003551A MX 2013003551 A MX2013003551 A MX 2013003551A MX 2013003551 A MX2013003551 A MX 2013003551A MX 2013003551 A MX2013003551 A MX 2013003551A MX 2013003551 A MX2013003551 A MX 2013003551A
Authority
MX
Mexico
Prior art keywords
solid state
state forms
hcv inhibitor
potent hcv
potent
Prior art date
Application number
MX2013003551A
Other languages
English (en)
Inventor
Shirlynn Chen
Zeren Wang
Richard Varsolona
Rolf-Stefan Brickl
Danping Li
Jihchin Chung
Mayur Suryakant Dudhedia
Zhi-Hui Lu
Siddharthya Mujumdar
Chitra Telang
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44759789&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013003551(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2013003551A publication Critical patent/MX2013003551A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Esta invención se refiere a nuevas formas de la sal de sodio del siguiente Compuesto (1), y a métodos para su preparación, a sus composiciones farmacéuticas, y a su uso en el tratamiento de la infección por el Virus de la Hepatitis C (VHC): (ver Fórmula).
MX2013003551A 2010-09-30 2011-09-23 Formas en estado solido de un potente inhibidor del vch. MX2013003551A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38824210P 2010-09-30 2010-09-30
PCT/US2011/052869 WO2012044520A1 (en) 2010-09-30 2011-09-23 Solid state forms of a potent hcv inhibitor

Publications (1)

Publication Number Publication Date
MX2013003551A true MX2013003551A (es) 2013-05-01

Family

ID=44759789

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013003551A MX2013003551A (es) 2010-09-30 2011-09-23 Formas en estado solido de un potente inhibidor del vch.

Country Status (21)

Country Link
US (2) US8598183B2 (es)
EP (1) EP2621921A1 (es)
JP (1) JP2013543495A (es)
KR (1) KR20130108326A (es)
CN (1) CN103153987A (es)
AP (1) AP2013006733A0 (es)
AR (1) AR083256A1 (es)
AU (1) AU2011307346A1 (es)
BR (1) BR112013007700A2 (es)
CA (1) CA2813179A1 (es)
CL (1) CL2013000578A1 (es)
CO (1) CO6700844A2 (es)
EA (1) EA201300422A1 (es)
EC (1) ECSP13012552A (es)
MA (1) MA34548B1 (es)
MX (1) MX2013003551A (es)
PE (1) PE20131351A1 (es)
SG (1) SG188376A1 (es)
TW (1) TW201307327A (es)
UY (1) UY33632A (es)
WO (1) WO2012044520A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013003551A (es) * 2010-09-30 2013-05-01 Boehringer Ingelheim Int Formas en estado solido de un potente inhibidor del vch.
US9067918B2 (en) * 2011-12-06 2015-06-30 Sanofi Crystalline forms of 2-(2-methylamino-pyrimidin-4-yl)-1H-indole-5-carboxylic acid [ (S)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl ]-amide
US20130261134A1 (en) * 2012-03-30 2013-10-03 Boehringer Ingelheim International Gmbh Mesylate salt forms of a potent hcv inhibitor
WO2014138374A1 (en) 2013-03-08 2014-09-12 Boehringer Ingelheim International Gmbh Oral combination therapy for treating hcv infection in specific patient sub-population

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2308955T5 (es) 1993-09-28 2012-04-03 R.P. Scherer Gmbh Fabricación de cápsulas de gelatina blanda
US5821242A (en) * 1996-06-06 1998-10-13 Eli Lilly And Company Anti-viral compounds
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
EP2626354A1 (en) 2004-02-20 2013-08-14 Boehringer Ingelheim International GmbH Viral polymerase inhibitors
MX2007009689A (es) 2005-02-11 2007-09-13 Boehringer Ingelheim Int Proceso para preparar indoles disustituidos en posicion 2,3.
JP5284101B2 (ja) 2005-11-09 2013-09-11 ノバルティス アーゲー 一時可塑剤を用いる医薬組成物の製造法
MX2013003551A (es) * 2010-09-30 2013-05-01 Boehringer Ingelheim Int Formas en estado solido de un potente inhibidor del vch.

Also Published As

Publication number Publication date
WO2012044520A1 (en) 2012-04-05
CA2813179A1 (en) 2012-04-05
AU2011307346A1 (en) 2013-02-21
KR20130108326A (ko) 2013-10-02
AR083256A1 (es) 2013-02-13
SG188376A1 (en) 2013-04-30
EA201300422A1 (ru) 2013-09-30
US8598183B2 (en) 2013-12-03
JP2013543495A (ja) 2013-12-05
TW201307327A (zh) 2013-02-16
PE20131351A1 (es) 2013-12-04
CL2013000578A1 (es) 2013-08-02
UY33632A (es) 2012-04-30
BR112013007700A2 (pt) 2019-09-24
ECSP13012552A (es) 2013-06-28
AP2013006733A0 (en) 2013-02-28
US20120122887A1 (en) 2012-05-17
CO6700844A2 (es) 2013-06-28
MA34548B1 (fr) 2013-09-02
EP2621921A1 (en) 2013-08-07
CN103153987A (zh) 2013-06-12
US20140057928A1 (en) 2014-02-27

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal