MX2012011549A - Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas. - Google Patents
Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas.Info
- Publication number
- MX2012011549A MX2012011549A MX2012011549A MX2012011549A MX2012011549A MX 2012011549 A MX2012011549 A MX 2012011549A MX 2012011549 A MX2012011549 A MX 2012011549A MX 2012011549 A MX2012011549 A MX 2012011549A MX 2012011549 A MX2012011549 A MX 2012011549A
- Authority
- MX
- Mexico
- Prior art keywords
- substituted
- acaricides
- insecticides
- phenyl
- isoxazoline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente invención se refiere a derivados de isoxazolina sustituida de Fórmula (1) (ver fórmula) o una sal aceptable desde el punto de vista veterinario del mismo, con actividad parasiticida, composiciones del mismo, y su uso como un parasiticida en animales o pájaros, en la que R1a, R1b, R1c, R2, R3 y n son como se describen en el presente documento.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32214410P | 2010-04-08 | 2010-04-08 | |
US201161431107P | 2011-01-10 | 2011-01-10 | |
PCT/IB2011/051129 WO2011124998A1 (en) | 2010-04-08 | 2011-03-17 | Substituted 3,5- di phenyl - isoxazoline derivatives as insecticides and acaricides |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012011549A true MX2012011549A (es) | 2013-01-29 |
Family
ID=44169107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012011549A MX2012011549A (es) | 2010-04-08 | 2011-03-17 | Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20110251247A1 (es) |
EP (1) | EP2556060A1 (es) |
JP (1) | JP2013523805A (es) |
CN (1) | CN102933563A (es) |
AR (1) | AR080841A1 (es) |
AU (1) | AU2011236510A1 (es) |
CA (1) | CA2794428A1 (es) |
CL (1) | CL2012002770A1 (es) |
MX (1) | MX2012011549A (es) |
WO (1) | WO2011124998A1 (es) |
Families Citing this family (69)
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DK3354650T3 (da) | 2008-12-19 | 2022-05-30 | Vertex Pharma | Forbindelser der er nyttige som inhibitorer af ATR-kinase |
TWI487486B (zh) | 2009-12-01 | 2015-06-11 | Syngenta Participations Ag | 以異唑啉衍生物為主之殺蟲化合物 |
JP2013529200A (ja) | 2010-05-12 | 2013-07-18 | バーテックス ファーマシューティカルズ インコーポレイテッド | Atrキナーゼ阻害剤として有用な化合物 |
JP2013526538A (ja) | 2010-05-12 | 2013-06-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | Atrキナーゼ阻害剤として有用な化合物 |
AU2011253025A1 (en) | 2010-05-12 | 2012-11-29 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
WO2011143425A2 (en) | 2010-05-12 | 2011-11-17 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
EP2569289A1 (en) | 2010-05-12 | 2013-03-20 | Vertex Pharmaceuticals Incorporated | Pyrazines useful as inhibitors of atr kinase |
AU2011253021A1 (en) | 2010-05-12 | 2012-11-29 | Vertex Pharmaceuticals Incorporated | 2 -aminopyridine derivatives useful as inhibitors of ATR kinase |
MX2013000103A (es) | 2010-06-23 | 2013-06-13 | Vertex Pharma | Derivados de pirrolo-pirazina utiles como inhibidores de cinasa art. |
CN105616406B (zh) | 2010-12-27 | 2019-12-13 | 英特维特国际股份有限公司 | 外用局部异噁唑啉制剂 |
KR20140027974A (ko) | 2011-04-05 | 2014-03-07 | 버텍스 파마슈티칼스 인코포레이티드 | Tra 키나제의 억제제로서 유용한 아미노피라진 화합물 |
WO2012165186A1 (en) * | 2011-05-31 | 2012-12-06 | Sumitomo Chemical Company, Limited | Animal ectoparasite-controlling agent |
JP2014517079A (ja) | 2011-06-22 | 2014-07-17 | バーテックス ファーマシューティカルズ インコーポレイテッド | Atrキナーゼ阻害剤として有用な化合物 |
EP2723745A1 (en) | 2011-06-22 | 2014-04-30 | Vertex Pharmaceuticals Inc. | Compounds useful as inhibitors of atr kinase |
JP2014522818A (ja) | 2011-06-22 | 2014-09-08 | バーテックス ファーマシューティカルズ インコーポレイテッド | Atrキナーゼ阻害剤として有用な化合物 |
SG11201401093WA (en) | 2011-09-30 | 2014-04-28 | Vertex Pharma | Processes for making compounds useful as inhibitors of atr kinase |
EP2751088B1 (en) | 2011-09-30 | 2016-04-13 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
JP6162126B2 (ja) | 2011-09-30 | 2017-08-23 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Atr阻害剤による膵臓癌及び非小細胞肺癌の治療 |
WO2013049720A1 (en) | 2011-09-30 | 2013-04-04 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
US8846686B2 (en) | 2011-09-30 | 2014-09-30 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
JP2015502925A (ja) | 2011-11-09 | 2015-01-29 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Atrキナーゼの阻害剤として有用なピラジン化合物 |
US8846918B2 (en) | 2011-11-09 | 2014-09-30 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
US8841337B2 (en) | 2011-11-09 | 2014-09-23 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
US8846917B2 (en) | 2011-11-09 | 2014-09-30 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
EP2776420A1 (en) | 2011-11-09 | 2014-09-17 | Vertex Pharmaceuticals Incorporated | Pyrazine compounds useful as inhibitors of atr kinase |
PT109395B (pt) | 2012-02-06 | 2020-10-01 | Boehringer Ingelheim Animal Health USA Inc. | Composições veterinárias orais parasiticidas compreendendo agentes activos de actuação sistémica, métodos e as suas utilizações |
JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
AU2013245008B2 (en) | 2012-04-04 | 2017-03-30 | Intervet International B.V. | Soft chewable pharmaceutical products |
HUE035253T2 (en) | 2012-04-05 | 2018-05-02 | Vertex Pharma | Compounds and combination therapies useful as inhibitors of ATR kinase |
CN104271568B (zh) | 2012-05-09 | 2016-05-04 | 硕腾服务有限责任公司 | 作为抗寄生虫剂的氮杂环丁烷衍生物 |
EP2904406B1 (en) | 2012-10-04 | 2018-03-21 | Vertex Pharmaceuticals Incorporated | Method for measuring atr inhibition mediated increases in dna damage |
EP2909202A1 (en) | 2012-10-16 | 2015-08-26 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
US9532946B2 (en) | 2012-11-20 | 2017-01-03 | Intervet Inc. | Manufacturing of semi-plastic pharmaceutical dosage units |
HUE052808T2 (hu) | 2012-12-07 | 2021-05-28 | Vertex Pharma | Pirazolo[1,5-A]pirimidinek alkalmazása ATR kináz inhibítorként, rákos megbetegedések kezelésére |
EP2970286A1 (en) | 2013-03-15 | 2016-01-20 | Vertex Pharmaceuticals Inc. | Fused pyrazolopyrimidine derivatives useful as inhibitors of atr kinase |
DK3063144T3 (da) | 2013-11-01 | 2021-10-25 | Boehringer Ingelheim Animal Health Usa Inc | Antiparasitære og pesticid-isoxazolinforbindelser |
RS59679B1 (sr) | 2013-12-06 | 2020-01-31 | Vertex Pharma | Jedinjenje 2-amino-6-fluoro-n-[5-fluoro-piridin-3-il]pirazolo[1,5-a]pirimidin-3-karboksamida korisno kao inhibitor atr kinaze, njegovo dobijanje, različiti čvrsti oblici i njegovi radioaktivno obeleženi derivati |
NZ726251A (en) | 2014-04-17 | 2017-11-24 | Merial Inc | Use of malononitrile compounds for protecting animals from parasites |
SI3152212T1 (sl) | 2014-06-05 | 2020-06-30 | Vertex Pharmaceuticals Inc. | Radioaktivno označeni derivati 2-amino-6-fluoro-N-(5-fluoro-piridin-3-IL)-pirazolo (1,5-A)pirimidin-3- karboksamidne spojine, koristni kot inhibitor kinaze ATR, priprava navedene spojine in njene različne trdne oblike |
RS59054B1 (sr) | 2014-06-17 | 2019-08-30 | Vertex Pharma | Postupak za lečenje raka korišćenjem kombinacije chk1 i atr inhibitora |
UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
EP3298027B1 (en) | 2015-05-20 | 2021-04-28 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
ES2920394T3 (es) | 2015-06-23 | 2022-08-03 | Intervet Int Bv | Solución de isoxazolina que contiene vitamina E para usar con agua potable desinfectada |
WO2017059357A1 (en) | 2015-09-30 | 2017-04-06 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of dna damaging agents and atr inhibitors |
US11046695B2 (en) | 2015-11-11 | 2021-06-29 | Zealand Pharma A/S | Fragment synthesis of substituted cyclic peptides |
JP2019535655A (ja) | 2016-10-14 | 2019-12-12 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 殺虫性及び殺寄生虫性ビニルイソオキサゾリン化合物 |
JP7035044B2 (ja) | 2016-11-11 | 2022-03-14 | ジーランド ファーマ エー/エス | α4β7インテグリンを標的とする環状ペプチド多量体 |
MX2019005628A (es) | 2016-11-16 | 2019-12-18 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos depsipeptidos antihelminticos. |
US11286281B2 (en) | 2017-05-10 | 2022-03-29 | Zealand Pharma A/S | Homodetic cyclic peptides targeting alpha-4-beta-7 integrin |
BR112020003217A2 (pt) | 2017-08-14 | 2020-10-06 | Boehringer Ingelheim Animal Health USA Inc. | compostos pesticidas e parasiticidas de pirazolisoxazolina |
EP4316522A3 (en) | 2017-11-07 | 2024-04-03 | Intervet International B.V. | Injectable isoxazoline pharmaceutical compositions and their use against parasite infestation |
AR113997A1 (es) | 2017-12-21 | 2020-07-08 | Intervet Int Bv | Composiciones antiparasitarias para unción dorsal continua |
CA3106092A1 (en) | 2018-07-09 | 2020-01-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anthelminthic heterocyclic compounds |
US11773066B2 (en) | 2018-11-20 | 2023-10-03 | Boehringer Ingelheim Animal Health USA Inc. | Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof |
PE20220281A1 (es) | 2019-03-19 | 2022-02-25 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos |
JP2022531590A (ja) | 2019-05-03 | 2022-07-07 | インターベット インターナショナル ベー. フェー. | 注射可能な医薬組成物及びその使用 |
BR112022011046A2 (pt) | 2019-12-16 | 2022-08-23 | Intervet Int Bv | Composição para controle de piolhos em avinos |
AU2020409532A1 (en) | 2019-12-16 | 2022-05-12 | Intervet International B.V. | Composition for lice control |
ES2973362T3 (es) | 2019-12-16 | 2024-06-19 | Intervet Int Bv | Control de parásitos en rumiantes |
PT4153133T (pt) | 2020-05-20 | 2024-01-12 | Intervet Int Bv | Composições farmacêuticas injetáveis e utilizações das mesmas |
JP2023528822A (ja) | 2020-05-29 | 2023-07-06 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性複素環式化合物 |
US20240116854A1 (en) | 2021-01-27 | 2024-04-11 | Intervet Inc. | Cyclopropylamide compounds against parasites in fish |
CA3209562A1 (en) | 2021-01-27 | 2022-08-04 | Intervet International B.V. | Cyclopropylamide compounds against parasites in fish |
EP4291551A1 (en) | 2021-02-11 | 2023-12-20 | Basf Se | Substituted isoxazoline derivatives |
EP4043444A1 (en) | 2021-02-11 | 2022-08-17 | Basf Se | Substituted isoxazoline derivatives |
WO2022258797A1 (en) | 2021-06-11 | 2022-12-15 | Intervet International B.V. | Tick control methods |
CN117545473A (zh) | 2021-06-25 | 2024-02-09 | 英特维特国际股份有限公司 | 适口兽用组合物 |
US20230312207A1 (en) | 2022-02-17 | 2023-10-05 | Boehringer Ingelheim Vetmedica Gmbh | Method and system for providing a fluid product mailer |
WO2024047241A1 (en) | 2022-09-02 | 2024-03-07 | Intervet International B.V. | Treatment of fasciolosis |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW524667B (en) | 1996-12-05 | 2003-03-21 | Pfizer | Parasiticidal pyrazoles |
JP4549021B2 (ja) | 2001-03-30 | 2010-09-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ベンゼン化合物およびその塩 |
JP4451849B2 (ja) | 2003-11-28 | 2010-04-14 | 日本曹達株式会社 | アリール複素環誘導体および農園芸用殺菌剤および殺虫剤 |
GB0329314D0 (en) | 2003-12-18 | 2004-01-21 | Pfizer Ltd | Substituted arylpyrazoles |
ZA200607637B (en) | 2004-03-05 | 2008-05-28 | Nissan Chemical Ind Ltd | Isoxazoline-substituted benzamide compound and noxious organism control agent |
DE102004030753A1 (de) * | 2004-06-25 | 2006-01-19 | Bayer Cropscience Ag | 3'-Alkoxy spirocyclische Tetram- und Tretronsäuren |
AU2006285613B2 (en) | 2005-09-02 | 2011-11-17 | Nissan Chemical Corporation | Isoxazoline-substituted benzamide compound and harmful organism-controlling agent |
EP1997813B1 (en) | 2006-03-10 | 2010-05-05 | Nissan Chemical Industries, Ltd. | Substituted isoxazoline compound and pest control agent |
JP2008239611A (ja) | 2007-02-27 | 2008-10-09 | Nissan Chem Ind Ltd | イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤 |
KR20090130064A (ko) * | 2007-04-10 | 2009-12-17 | 바이엘 크롭사이언스 아게 | 살충성 아릴 이속사졸린 유도체 |
JP2008260691A (ja) * | 2007-04-10 | 2008-10-30 | Bayer Cropscience Ag | 殺虫性アリールイソオキサゾリン誘導体 |
AU2009294050B2 (en) * | 2008-09-18 | 2011-11-17 | Nippon Soda Co., Ltd. | Nitrogen-containing heterocyclic compound and pest control agent |
-
2011
- 2011-03-17 EP EP11715039A patent/EP2556060A1/en not_active Withdrawn
- 2011-03-17 JP JP2013503195A patent/JP2013523805A/ja not_active Withdrawn
- 2011-03-17 CN CN2011800176874A patent/CN102933563A/zh active Pending
- 2011-03-17 AU AU2011236510A patent/AU2011236510A1/en not_active Abandoned
- 2011-03-17 MX MX2012011549A patent/MX2012011549A/es not_active Application Discontinuation
- 2011-03-17 CA CA2794428A patent/CA2794428A1/en not_active Abandoned
- 2011-03-17 WO PCT/IB2011/051129 patent/WO2011124998A1/en active Application Filing
- 2011-04-06 US US13/080,721 patent/US20110251247A1/en not_active Abandoned
- 2011-04-07 AR ARP110101163A patent/AR080841A1/es not_active Application Discontinuation
-
2012
- 2012-10-02 CL CL2012002770A patent/CL2012002770A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2011124998A1 (en) | 2011-10-13 |
AU2011236510A1 (en) | 2012-10-11 |
CN102933563A (zh) | 2013-02-13 |
AR080841A1 (es) | 2012-05-09 |
US20110251247A1 (en) | 2011-10-13 |
EP2556060A1 (en) | 2013-02-13 |
CL2012002770A1 (es) | 2013-03-01 |
CA2794428A1 (en) | 2011-10-13 |
JP2013523805A (ja) | 2013-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC | Change of company name or juridical status |
Owner name: THE RUHOF CORPORATION |
|
FA | Abandonment or withdrawal |