MX2012001689A - Heterociclos microbicidas. - Google Patents
Heterociclos microbicidas.Info
- Publication number
- MX2012001689A MX2012001689A MX2012001689A MX2012001689A MX2012001689A MX 2012001689 A MX2012001689 A MX 2012001689A MX 2012001689 A MX2012001689 A MX 2012001689A MX 2012001689 A MX2012001689 A MX 2012001689A MX 2012001689 A MX2012001689 A MX 2012001689A
- Authority
- MX
- Mexico
- Prior art keywords
- sup
- phenyl
- cyano
- halogen
- independently
- Prior art date
Links
- 230000003641 microbiacidal effect Effects 0.000 title abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- -1 cyano, hydroxy Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002883 imidazolyl group Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 2
- 125000004076 pyridyl group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000000855 fungicidal effect Effects 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invención trata acerca de compuestos heterocíclicos de fórmula I los cuales tiene actividad microbicida, en particular actividad fungicida así como acerca de métodos de utilización de los compuestos de fórmula I para controlar microbios: (ver fórmula (I)) en donde A es x-C(R10R11)-C(=0)-, x-C(R12R13)-C(=S)-, x-O-C(=O)-, x-OC(=S)-, x-N(R14)-C(=O)-, x-N(R15)-C(=S)-, x-C(R16R17)-SO2- o x-N=C(R30)-, en cada caso x representa el enlace que está conectado a R1; T es CR18 o N; Y1, Y2, Y3, y Y4 son independientemente CR19 o N; Q es O o S; nes 1 o 2; p es 1 o 2, con la condición de que cuando n es 2, p es 1. R1 es fenilo, piridilo, imidazolilo, o pirazolilo; en donde cada uno de fenilo, piridilo, imidazolilo y pirazolilo están sustituidos opcionalmente con entre 1 y 3 sustituyentes escogidos independientemente entre alquilo C1-C4, haloalquilo C1-C4, halógeno, ciano, hidroxi y amino; R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18, R19 y R30 son, cada uno independientemente, hidrógeno, halógeno, ciano, alquilo C1-C4, o haloalquilo C1-C4 R8, R14 y R15 son, cada uno independientemente, hidrógeno o alquilo C1-C4 y R9 es fenilo, bencilo o el grupo (a) (ver fórmula (a)) en donde cada uno de fenilo, bencilo y el grupo (a) están sustituidos opcionalmente con entre 1 y 3 sustituyentes escogidos independientemente entre alquilo C1-C4, haloalquilo C1-C4, halógeno, ciano, hidroxi y amino; o una sal o un N-óxido del mismo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09167741 | 2009-08-12 | ||
| PCT/EP2010/061464 WO2011018415A2 (en) | 2009-08-12 | 2010-08-06 | Microbiocidal heterocycles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012001689A true MX2012001689A (es) | 2012-02-22 |
Family
ID=42683487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012001689A MX2012001689A (es) | 2009-08-12 | 2010-08-06 | Heterociclos microbicidas. |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US8367844B2 (es) |
| EP (1) | EP2464630B1 (es) |
| JP (1) | JP5778674B2 (es) |
| KR (1) | KR101750027B1 (es) |
| CN (1) | CN102471277B (es) |
| AP (1) | AP3383A (es) |
| AR (1) | AR077835A1 (es) |
| AU (1) | AU2010283767B2 (es) |
| BR (1) | BR112012003124A2 (es) |
| CA (1) | CA2768636C (es) |
| CL (1) | CL2012000339A1 (es) |
| CO (1) | CO6612179A2 (es) |
| CR (1) | CR20120064A (es) |
| EA (1) | EA021137B1 (es) |
| ES (1) | ES2588330T3 (es) |
| GE (1) | GEP20146113B (es) |
| HN (1) | HN2012000308A (es) |
| HR (1) | HRP20160951T1 (es) |
| HU (1) | HUE029097T2 (es) |
| IL (1) | IL217645A (es) |
| JO (1) | JO3140B1 (es) |
| MX (1) | MX2012001689A (es) |
| MY (1) | MY157410A (es) |
| NI (1) | NI201200025A (es) |
| NZ (1) | NZ597503A (es) |
| PL (1) | PL2464630T3 (es) |
| PT (1) | PT2464630T (es) |
| SA (1) | SA110310646B1 (es) |
| TW (1) | TWI488849B (es) |
| UA (1) | UA107938C2 (es) |
| UY (1) | UY32840A (es) |
| WO (1) | WO2011018415A2 (es) |
| ZA (1) | ZA201200368B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130100903A (ko) | 2010-04-28 | 2013-09-12 | 바이엘 크롭사이언스 아게 | 살진균제로서의 케토헤테로아릴피페리딘 및 케토헤테로아릴피페라진 유도체 |
| BR112012030184A2 (pt) * | 2010-05-27 | 2015-12-29 | Bayer Cropscience Ag | derivados de ácido piridinilcarboxílico como fungicidas |
| US20120122928A1 (en) | 2010-08-11 | 2012-05-17 | Bayer Cropscience Ag | Heteroarylpiperidine and -Piperazine Derivatives as Fungicides |
| US8759527B2 (en) | 2010-08-25 | 2014-06-24 | Bayer Cropscience Ag | Heteroarylpiperidine and -piperazine derivatives as fungicides |
| WO2012055837A1 (de) | 2010-10-27 | 2012-05-03 | Bayer Cropscience Ag | Heteroarylpiperidin und -piperazinderivate als fungizide |
| MX359992B (es) * | 2011-06-30 | 2018-10-18 | Syngenta Participations Ag | Heterociclos microbiocidas. |
| EP2921493B1 (de) | 2011-12-27 | 2017-08-16 | Bayer Intellectual Property GmbH | Heteroarylpiperidin und -piperazinderivate |
| CA2861020C (en) | 2012-02-02 | 2018-07-17 | Actelion Pharmaceuticals Ltd | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives and their use as cxcr3 receptor modulators |
| US10035790B2 (en) * | 2012-10-19 | 2018-07-31 | Exelixis, Inc. | RORγ modulators |
| EP2801575A1 (en) | 2013-05-07 | 2014-11-12 | Bayer CropScience AG | Heteroaryldihydropyridine derivatives as fungicides |
| US9717243B2 (en) | 2013-06-24 | 2017-08-01 | Bayer Cropscience Aktiengesellschaft | Piperidinecarboxylic acid derivatives as fungicides |
| ES2671323T3 (es) | 2013-07-22 | 2018-06-06 | Idorsia Pharmaceuticals Ltd | Derivados 1¿(piperazin¿1¿il)¿2¿([1,2,4]triazol¿1¿il)¿etanona |
| EP3039023A1 (en) | 2013-08-28 | 2016-07-06 | Bayer CropScience Aktiengesellschaft | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides |
| WO2015144571A1 (en) | 2014-03-24 | 2015-10-01 | Bayer Cropscience Ag | Phenylpiperidinecarboxamide derivatives as fungicides |
| AR099789A1 (es) | 2014-03-24 | 2016-08-17 | Actelion Pharmaceuticals Ltd | Derivados de 8-(piperazin-1-il)-1,2,3,4-tetrahidro-isoquinolina |
| US10111433B2 (en) | 2014-07-31 | 2018-10-30 | Syngenta Participations Ag | Fungicidal compositions |
| WO2016024350A1 (ja) | 2014-08-13 | 2016-02-18 | 株式会社エス・ディー・エス バイオテック | 縮合１１員環化合物及びそれらを含有する農園芸用殺菌剤 |
| ES2709985T3 (es) | 2015-01-15 | 2019-04-22 | Idorsia Pharmaceuticals Ltd | Derivados de hidroxialquil-piperazina como moduladores del receptor CXCR3 |
| AR103399A1 (es) | 2015-01-15 | 2017-05-10 | Actelion Pharmaceuticals Ltd | Derivados de (r)-2-metil-piperazina como moduladores del receptor cxcr3 |
| PT3415496T (pt) | 2016-02-08 | 2021-10-25 | Gowan Crop Prot Limited | Processo para a preparação do composto 1,2-benzenodimetanol |
| WO2017138069A1 (ja) | 2016-02-08 | 2017-08-17 | 株式会社エス・ディー・エス バイオテック | 殺菌性組成物 |
| EP3454945B1 (en) * | 2016-05-12 | 2022-01-19 | The Regents Of The University Of Michigan | Ash1l inhibitors and methods of treatment therewith |
| WO2019040703A1 (en) | 2017-08-23 | 2019-02-28 | Magna Mirrors Of America, Inc. | INDOOR REAR VIEW MOUNT WITH FULL SCREEN VIDEO DISPLAY |
| WO2019094772A1 (en) | 2017-11-10 | 2019-05-16 | The Regents Of The University Of Michigan | Ash1l degraders and methods of treatment therewith |
| CN114380802B (zh) * | 2022-01-07 | 2023-11-17 | 贵州大学 | 一类含咔唑基咪唑盐类化合物及其制备方法和应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340685C (en) | 1988-07-29 | 1999-07-27 | Frederick Meins | Dna sequences encoding polypeptides having beta-1,3-glucanase activity |
| EP0392225B1 (en) | 1989-03-24 | 2003-05-28 | Syngenta Participations AG | Disease-resistant transgenic plants |
| US5639949A (en) | 1990-08-20 | 1997-06-17 | Ciba-Geigy Corporation | Genes for the synthesis of antipathogenic substances |
| US5523302A (en) * | 1993-11-24 | 1996-06-04 | The Du Pont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
| CN1213373A (zh) | 1996-03-11 | 1999-04-07 | 诺瓦提斯公司 | 农药用嘧啶－4－酮衍生物 |
| US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
| GB0214406D0 (en) | 2002-06-21 | 2002-07-31 | Plant Bioscience Ltd | Plant-derived transferase genes |
| EP1567493B1 (en) | 2002-11-26 | 2009-03-18 | Pfizer Products Inc. | Phenyl substituted piperidine compounds for use as ppar activators |
| KR20060003353A (ko) * | 2003-04-15 | 2006-01-10 | 머크 앤드 캄파니 인코포레이티드 | 케모킨 수용체의벤족사지닐-아미도사이클로펜틸-헤테로사이클릭 조절제 |
| US7868205B2 (en) * | 2003-09-24 | 2011-01-11 | Methylgene Inc. | Inhibitors of histone deacetylase |
| US8076338B2 (en) * | 2004-04-23 | 2011-12-13 | Exelixis, Inc. | Kinase modulators and methods of use |
| JP2008500328A (ja) * | 2004-05-25 | 2008-01-10 | ファイザー・プロダクツ・インク | 新規な使用 |
| TW200738701A (en) * | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| WO2008013622A2 (en) | 2006-07-27 | 2008-01-31 | E. I. Du Pont De Nemours And Company | Fungicidal azocyclic amides |
| WO2008091594A2 (en) | 2007-01-24 | 2008-07-31 | E. I. Du Pont De Nemours And Company | Fungicidal mixtures |
| PL2121660T3 (pl) | 2007-01-25 | 2015-06-30 | Du Pont | Amidy grzybobójcze |
| WO2009034390A1 (en) * | 2007-09-14 | 2009-03-19 | Arrow Therapeutics Limited | Heterocyclic derivatives and their use in treating hepatitis c |
| TWI428091B (zh) | 2007-10-23 | 2014-03-01 | Du Pont | 殺真菌劑混合物 |
| WO2009098576A1 (en) * | 2008-02-05 | 2009-08-13 | Pfizer Inc. | Pyridinyl amides for the treatment of cns and metabolic disorders |
-
2010
- 2010-06-08 UA UAA201202483A patent/UA107938C2/uk unknown
- 2010-08-06 CN CN201080035394.4A patent/CN102471277B/zh not_active Expired - Fee Related
- 2010-08-06 PL PL10739639.2T patent/PL2464630T3/pl unknown
- 2010-08-06 MX MX2012001689A patent/MX2012001689A/es active IP Right Grant
- 2010-08-06 NZ NZ597503A patent/NZ597503A/xx not_active IP Right Cessation
- 2010-08-06 CA CA2768636A patent/CA2768636C/en not_active Expired - Fee Related
- 2010-08-06 BR BR112012003124-4A patent/BR112012003124A2/pt not_active Application Discontinuation
- 2010-08-06 WO PCT/EP2010/061464 patent/WO2011018415A2/en active Application Filing
- 2010-08-06 ES ES10739639.2T patent/ES2588330T3/es active Active
- 2010-08-06 MY MYPI2011006187A patent/MY157410A/en unknown
- 2010-08-06 HU HUE10739639A patent/HUE029097T2/en unknown
- 2010-08-06 JP JP2012524206A patent/JP5778674B2/ja not_active Expired - Fee Related
- 2010-08-06 US US13/390,023 patent/US8367844B2/en not_active Expired - Fee Related
- 2010-08-06 PT PT107396392T patent/PT2464630T/pt unknown
- 2010-08-06 AP AP2012006152A patent/AP3383A/xx active
- 2010-08-06 EP EP10739639.2A patent/EP2464630B1/en not_active Not-in-force
- 2010-08-06 AU AU2010283767A patent/AU2010283767B2/en not_active Ceased
- 2010-08-06 EA EA201200259A patent/EA021137B1/ru not_active IP Right Cessation
- 2010-08-06 GE GEAP201012624A patent/GEP20146113B/en unknown
- 2010-08-06 KR KR1020127006326A patent/KR101750027B1/ko active IP Right Grant
- 2010-08-09 SA SA110310646A patent/SA110310646B1/ar unknown
- 2010-08-10 AR ARP100102924A patent/AR077835A1/es active IP Right Grant
- 2010-08-10 TW TW099126588A patent/TWI488849B/zh not_active IP Right Cessation
- 2010-08-10 JO JOP/2010/0282A patent/JO3140B1/ar active
- 2010-08-12 UY UY0001032840A patent/UY32840A/es not_active Application Discontinuation
-
2012
- 2012-01-17 ZA ZA2012/00368A patent/ZA201200368B/en unknown
- 2012-01-19 IL IL217645A patent/IL217645A/en not_active IP Right Cessation
- 2012-02-08 CO CO12022027A patent/CO6612179A2/es active IP Right Grant
- 2012-02-08 NI NI201200025A patent/NI201200025A/es unknown
- 2012-02-08 CR CR20120064A patent/CR20120064A/es unknown
- 2012-02-09 HN HN2012000308A patent/HN2012000308A/es unknown
- 2012-02-09 CL CL2012000339A patent/CL2012000339A1/es unknown
-
2013
- 2013-02-05 US US13/759,761 patent/US20130144064A1/en not_active Abandoned
-
2016
- 2016-07-26 HR HRP20160951TT patent/HRP20160951T1/hr unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |