MX2010003556A - Regimen de tratamiento para trastornos proliferantes. - Google Patents
Regimen de tratamiento para trastornos proliferantes.Info
- Publication number
- MX2010003556A MX2010003556A MX2010003556A MX2010003556A MX2010003556A MX 2010003556 A MX2010003556 A MX 2010003556A MX 2010003556 A MX2010003556 A MX 2010003556A MX 2010003556 A MX2010003556 A MX 2010003556A MX 2010003556 A MX2010003556 A MX 2010003556A
- Authority
- MX
- Mexico
- Prior art keywords
- subject
- administering
- proliferative disorders
- treatment regime
- reovirus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/664—Amides of phosphorus acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/765—Reovirus; Rotavirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se proveen m?todos aqu? para el tratamiento o mejoramiento de un trastorno proliferante en un sujeto. El m?todo contiene las etapas de administrar al sujeto una dosis de un agente inmunosupresor seguido por la administraci?n al sujeto de una a cinco dosis de un reovirus. El agente inmunosupresor se administra al sujeto al menos aproximadamente 72 horas antes de la administraci?n del reovirus. Tambi?n se proveen aqu? m?todos para el tratamiento o mejoramiento de un trastorno proliferante en un sujeto incluyendo las etapas de administrar al sujeto un virus oncol?tico y un agente de modulaci?n de c?lula B. Tambi?n se proveen kits y composiciones farmac?uticas que contienen un virus oncol?tico y al menos un agente de modulaci?n de c?lulas B.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98171607P | 2007-10-22 | 2007-10-22 | |
PCT/CA2008/001865 WO2009052617A1 (en) | 2007-10-22 | 2008-10-22 | Treatment regime for proliferative disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010003556A true MX2010003556A (es) | 2010-04-21 |
Family
ID=40579002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010003556A MX2010003556A (es) | 2007-10-22 | 2008-10-22 | Regimen de tratamiento para trastornos proliferantes. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20100247622A1 (es) |
EP (1) | EP2211880A4 (es) |
JP (1) | JP2011500608A (es) |
CN (1) | CN101820892A (es) |
AU (1) | AU2008316276A1 (es) |
CA (1) | CA2699805A1 (es) |
MX (1) | MX2010003556A (es) |
WO (1) | WO2009052617A1 (es) |
ZA (1) | ZA201002167B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009135614A2 (en) * | 2008-05-09 | 2009-11-12 | Bayer Schering Pharma Aktiengesellschaft | Use of a virus regimen for the treatment of diseases |
CN102695520A (zh) * | 2008-05-27 | 2012-09-26 | 昂科利蒂克斯生物科技公司 | 调节间隙压力与溶瘤病毒的递送和分布 |
TW200950777A (en) * | 2008-05-27 | 2009-12-16 | Oncolytics Biotech Inc | Abrogating proinflammatory cytokine production during oncolytic reovirus therapy |
DE102013105144A1 (de) * | 2013-05-17 | 2014-11-20 | Arno Thaller | Pharmazeutisches Kombinationspräparat mit einem anti-idiotypischen Antikörperfragment |
CN106489075B (zh) * | 2014-07-11 | 2019-10-15 | 爱科谱迅病理研究公司 | 针对GTP酶KRas蛋白质(KRas)的SRM/MRM测定 |
BR112017018160A2 (pt) | 2015-02-25 | 2018-04-10 | Memorial Sloan-Kettering Cancer Center | uso do vírus vaccinia ankara modificado (mva) não replicante inativado como monoimunoterpia ou em combinação com agentes de bloqueio de pontos de verificação imunológica para tumores sólidos |
CN107847534B (zh) | 2015-04-17 | 2022-10-04 | 纪念斯隆凯特琳癌症中心 | Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用 |
EP3419648A4 (en) | 2016-02-25 | 2019-09-11 | Memorial Sloan-Kettering Cancer Center | ATTENUATED REPLICATION-VACCINE VIRUSES WITH THYMIDINE KINASE DELETION WITH AND WITHOUT EXPRESSION OF FLT3L OR HUMAN GM-CSF FOR ANTICANCER IMMUNOTHERAPY |
KR20180130500A (ko) | 2016-02-25 | 2018-12-07 | 메모리얼 슬로안 케터링 캔서 센터 | 인간 flt3l을 발현하는 재조합 mva 또는 mvaδe3l 및 고형 종양에 대한 면역요법제로서 그의 용도 |
CN106177955B (zh) * | 2016-08-18 | 2018-03-16 | 广州威溶特医药科技有限公司 | Bcl‑xL抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
CN108606982B (zh) | 2016-08-18 | 2020-02-04 | 广州威溶特医药科技有限公司 | Vcp抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
CN106265764B (zh) * | 2016-08-18 | 2018-03-16 | 广州威溶特医药科技有限公司 | Iap抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
US11242509B2 (en) | 2017-05-12 | 2022-02-08 | Memorial Sloan Kettering Cancer Center | Vaccinia virus mutants useful for cancer immunotherapy |
US20220111034A1 (en) * | 2019-01-18 | 2022-04-14 | Université Catholique de Louvain | Virus compositions |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL85035A0 (en) * | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
US5736137A (en) * | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
US5595721A (en) * | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
CN1281336A (zh) * | 1997-10-09 | 2001-01-24 | 病毒防御公司 | 使用病毒来治疗赘生物 |
TWI289158B (en) * | 2000-08-10 | 2007-11-01 | Oncolytics Biotech Inc | Method of producing infectious reovirus |
CA2428206C (en) * | 2000-11-09 | 2005-09-27 | Oncolytics Biotech Inc. | Methods for the treatment of cellular proliferative disorders |
AR035227A1 (es) * | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
WO2002074940A1 (en) * | 2001-03-16 | 2002-09-26 | Oncolytics Biotech, Inc. | Method of extracting virus from cell culture |
US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
WO2005002607A2 (en) * | 2003-07-07 | 2005-01-13 | Oncolytics Biotech Inc. | Oncolytic reoviruses for the treatment of neoplasms having activated pp2a or rac |
WO2007093036A1 (en) * | 2006-02-13 | 2007-08-23 | Oncolytics Biotech Inc. | Use of local immune suppression to enhance oncolytic viral therapy |
CA2678721C (en) * | 2007-03-12 | 2018-02-13 | Oncolytics Biotech Inc. | Reoviruses having modified sequences |
AR066649A1 (es) * | 2007-05-21 | 2009-09-02 | Oncolytics Biotech Inc | Reovirus mutantes y metodos de elaboracion y uso de los mismos |
-
2008
- 2008-10-22 MX MX2010003556A patent/MX2010003556A/es not_active Application Discontinuation
- 2008-10-22 CN CN200880110743A patent/CN101820892A/zh active Pending
- 2008-10-22 US US12/678,851 patent/US20100247622A1/en not_active Abandoned
- 2008-10-22 WO PCT/CA2008/001865 patent/WO2009052617A1/en active Application Filing
- 2008-10-22 JP JP2010529206A patent/JP2011500608A/ja active Pending
- 2008-10-22 CA CA2699805A patent/CA2699805A1/en not_active Abandoned
- 2008-10-22 AU AU2008316276A patent/AU2008316276A1/en not_active Abandoned
- 2008-10-22 EP EP08841201A patent/EP2211880A4/en not_active Withdrawn
-
2010
- 2010-03-26 ZA ZA2010/02167A patent/ZA201002167B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2008316276A1 (en) | 2009-04-30 |
ZA201002167B (en) | 2011-06-29 |
WO2009052617A1 (en) | 2009-04-30 |
CA2699805A1 (en) | 2009-04-30 |
US20100247622A1 (en) | 2010-09-30 |
AU2008316276A2 (en) | 2010-05-13 |
WO2009052617A9 (en) | 2010-08-05 |
EP2211880A4 (en) | 2012-11-14 |
JP2011500608A (ja) | 2011-01-06 |
CN101820892A (zh) | 2010-09-01 |
EP2211880A1 (en) | 2010-08-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |