MX2010001566A - Derivado de aminopirazolamida. - Google Patents
Derivado de aminopirazolamida.Info
- Publication number
- MX2010001566A MX2010001566A MX2010001566A MX2010001566A MX2010001566A MX 2010001566 A MX2010001566 A MX 2010001566A MX 2010001566 A MX2010001566 A MX 2010001566A MX 2010001566 A MX2010001566 A MX 2010001566A MX 2010001566 A MX2010001566 A MX 2010001566A
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- hydrogen atom
- aminopyrazole
- amide derivative
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
Se describe un compuesto representado por la fórmula (1) siguiente, o una sal farmacéuticamente aceptable del mismo, que es útil como agente para la prevención y/o tratamiento de la diabetes, etcétera: (ver fórmula 1) en esta fórmula, RA y RB representan independientemente un grupo alquilo sustituido opcionalmente o similar; RC representa un grupo alquilo sustituido opcionalmente o similar; RD representa un átomo de hidrógeno o similar; RE representa un átomo de hidrógeno o similar; y RF representa un grupo seleccionado de las fórmulas (G1) siguientes: (ver fórmula G1) en donde un átomo de hidrógeno sirve como una rama de enlace, o similar.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007204739 | 2007-08-06 | ||
JP2008074895 | 2008-03-24 | ||
PCT/JP2008/064085 WO2009020137A1 (ja) | 2007-08-06 | 2008-08-06 | アミノピラゾールアミド誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010001566A true MX2010001566A (es) | 2010-03-15 |
Family
ID=40341369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010001566A MX2010001566A (es) | 2007-08-06 | 2008-08-06 | Derivado de aminopirazolamida. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20110071289A1 (es) |
EP (1) | EP2189449A4 (es) |
JP (1) | JPWO2009020137A1 (es) |
KR (1) | KR20100044829A (es) |
CN (1) | CN101827820A (es) |
AU (1) | AU2008284746A1 (es) |
BR (1) | BRPI0815112A2 (es) |
CA (1) | CA2695437A1 (es) |
MX (1) | MX2010001566A (es) |
RU (1) | RU2010108325A (es) |
WO (1) | WO2009020137A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6155187B2 (ja) | 2010-03-30 | 2017-06-28 | ヴァーセオン コーポレイション | トロンビンの阻害剤としての多置換芳香族化合物 |
CN102633659B (zh) * | 2012-02-23 | 2013-12-04 | 浙江普洛康裕制药有限公司 | 一种反式4-氨基-1-羟基金刚烷盐酸盐的合成方法 |
JP2015129094A (ja) * | 2012-04-16 | 2015-07-16 | 大日本住友製薬株式会社 | アリールアミノピラゾール誘導体 |
CN108354933A (zh) | 2013-03-15 | 2018-08-03 | 维颂公司 | 作为丝氨酸蛋白酶抑制剂的多取代芳族化合物的制药用途 |
MX2015011567A (es) * | 2013-03-15 | 2016-04-25 | Verseon Corp | Halogeno-pirazoles como inhibidores de trombina. |
GB201309508D0 (en) | 2013-05-28 | 2013-07-10 | Redx Pharma Ltd | Compounds |
JP2017001954A (ja) * | 2013-11-08 | 2017-01-05 | 石原産業株式会社 | 含窒素飽和複素環化合物 |
CA2960790A1 (en) | 2014-09-17 | 2016-03-24 | Verseon Corporation | Pyrazolyl-substituted pyridone compounds as serine protease inhibitors |
LT3261639T (lt) | 2015-02-27 | 2022-11-25 | Verseon International Corporation | Pakaitiniai pirazolo junginiai kaip serino proteazės inhibitoriai |
CN111548317A (zh) * | 2020-04-28 | 2020-08-18 | 苏州纪元康生物科技有限公司 | 一种依法韦伦合成方法及制备其中间体方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8084467B2 (en) * | 1999-10-18 | 2011-12-27 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
US7393842B2 (en) * | 2001-08-31 | 2008-07-01 | University Of Connecticut | Pyrazole analogs acting on cannabinoid receptors |
CA2399791A1 (en) * | 2000-02-11 | 2001-08-16 | Bristol-Myers Squibb Company | Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases |
EP1615698B1 (en) | 2003-04-11 | 2010-09-29 | High Point Pharmaceuticals, LLC | New amide derivatives and pharmaceutical use thereof |
CN1832741A (zh) | 2003-08-07 | 2006-09-13 | 默克公司 | 作为11-β-羟甾类脱氢酶-1抑制剂的吡唑甲酰胺类 |
US7354938B2 (en) * | 2004-03-23 | 2008-04-08 | Amgen Inc. | Pyrazole compounds and uses related thereto |
US7880001B2 (en) * | 2004-04-29 | 2011-02-01 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme |
NZ553159A (en) * | 2004-08-30 | 2010-05-28 | Janssen Pharmaceutica Nv | N-Adamantan-2-yl-2-phenoxy-acetamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
-
2008
- 2008-08-06 US US12/672,236 patent/US20110071289A1/en not_active Abandoned
- 2008-08-06 EP EP08826977A patent/EP2189449A4/en not_active Withdrawn
- 2008-08-06 CN CN200880110520A patent/CN101827820A/zh active Pending
- 2008-08-06 RU RU2010108325/04A patent/RU2010108325A/ru not_active Application Discontinuation
- 2008-08-06 BR BRPI0815112-1A patent/BRPI0815112A2/pt not_active IP Right Cessation
- 2008-08-06 KR KR1020107002725A patent/KR20100044829A/ko not_active Application Discontinuation
- 2008-08-06 CA CA2695437A patent/CA2695437A1/en not_active Abandoned
- 2008-08-06 WO PCT/JP2008/064085 patent/WO2009020137A1/ja active Application Filing
- 2008-08-06 JP JP2009526467A patent/JPWO2009020137A1/ja active Pending
- 2008-08-06 AU AU2008284746A patent/AU2008284746A1/en not_active Abandoned
- 2008-08-06 MX MX2010001566A patent/MX2010001566A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101827820A (zh) | 2010-09-08 |
JPWO2009020137A1 (ja) | 2010-11-04 |
EP2189449A1 (en) | 2010-05-26 |
US20110071289A1 (en) | 2011-03-24 |
WO2009020137A1 (ja) | 2009-02-12 |
AU2008284746A1 (en) | 2009-02-12 |
KR20100044829A (ko) | 2010-04-30 |
EP2189449A4 (en) | 2011-10-19 |
BRPI0815112A2 (pt) | 2015-08-25 |
CA2695437A1 (en) | 2009-02-12 |
RU2010108325A (ru) | 2011-09-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |