MX2009011541A - Derivados de isoquinolinona como antagonistas nk3. - Google Patents

Derivados de isoquinolinona como antagonistas nk3.

Info

Publication number
MX2009011541A
MX2009011541A MX2009011541A MX2009011541A MX2009011541A MX 2009011541 A MX2009011541 A MX 2009011541A MX 2009011541 A MX2009011541 A MX 2009011541A MX 2009011541 A MX2009011541 A MX 2009011541A MX 2009011541 A MX2009011541 A MX 2009011541A
Authority
MX
Mexico
Prior art keywords
antagonists
isoquinolinone derivatives
derivatives
isoquinolinone
psychosis
Prior art date
Application number
MX2009011541A
Other languages
English (en)
Inventor
Nikolay Khanzhin
Jan Kehler
Karsten Juhl
Soeren Moeller Nielsen
Klaus Baek Simonsen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Priority claimed from PCT/DK2008/050092 external-priority patent/WO2008131779A1/en
Publication of MX2009011541A publication Critical patent/MX2009011541A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Se proveen derivados de isoquinolona de la fórmula general I (ver fórmula I) Los compuestos son antagonistas NK3 y útiles para el tratamiento de, por ejemplo: psicosis y esquizofrenia.
MX2009011541A 2007-04-26 2008-04-24 Derivados de isoquinolinona como antagonistas nk3. MX2009011541A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200700620 2007-04-26
PCT/DK2008/050092 WO2008131779A1 (en) 2007-04-26 2008-04-24 Isoquinolinone derivatives as nk3 antagonists

Publications (1)

Publication Number Publication Date
MX2009011541A true MX2009011541A (es) 2009-11-09

Family

ID=43034539

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011541A MX2009011541A (es) 2007-04-26 2008-04-24 Derivados de isoquinolinona como antagonistas nk3.

Country Status (11)

Country Link
EP (1) EP2150534B1 (es)
JP (1) JP2010524980A (es)
CN (1) CN101679276A (es)
AT (1) ATE540929T1 (es)
AU (1) AU2008243514A1 (es)
BR (1) BRPI0810996A2 (es)
CA (1) CA2683159A1 (es)
EA (1) EA200971002A1 (es)
ES (1) ES2378911T3 (es)
MX (1) MX2009011541A (es)
NZ (1) NZ580637A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102076820B1 (ko) 2013-10-21 2020-02-13 주식회사 대웅테라퓨틱스 신규한 항진균성 옥소다이하이드로피리딘카보하이드라자이드 유도체
US20170313665A1 (en) * 2014-11-03 2017-11-02 Bayer Pharma Aktiengesellschaft Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof
CN114605236B (zh) * 2022-03-16 2023-12-29 福建省中科生物股份有限公司 联芳基酚类化合物及其药物组合物、制备方法和应用

Also Published As

Publication number Publication date
JP2010524980A (ja) 2010-07-22
AU2008243514A1 (en) 2008-11-06
ATE540929T1 (de) 2012-01-15
EP2150534B1 (en) 2012-01-11
ES2378911T3 (es) 2012-04-19
CN101679276A (zh) 2010-03-24
CA2683159A1 (en) 2008-11-06
EA200971002A1 (ru) 2010-04-30
NZ580637A (en) 2011-07-29
EP2150534A1 (en) 2010-02-10
BRPI0810996A2 (pt) 2015-01-27

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Legal Events

Date Code Title Description
HH Correction or change in general
FA Abandonment or withdrawal