MX2009008617A - Uso de antagonistas de interleucina-23 para el tratamiento de infeccion. - Google Patents
Uso de antagonistas de interleucina-23 para el tratamiento de infeccion.Info
- Publication number
- MX2009008617A MX2009008617A MX2009008617A MX2009008617A MX2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A
- Authority
- MX
- Mexico
- Prior art keywords
- antagonists
- treatment
- infection
- infections
- viral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se proveen métodos y composiciones que comprenden antagonistas de IL-23 para el tratamiento de infecciones, tales como infecciones bacterianas, virales y fúngicas crónicas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88947507P | 2007-02-12 | 2007-02-12 | |
PCT/US2008/001717 WO2008153610A2 (en) | 2007-02-12 | 2008-02-08 | Use of il-23 antagonists for treatment of infection |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009008617A true MX2009008617A (es) | 2009-10-14 |
Family
ID=40130357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009008617A MX2009008617A (es) | 2007-02-12 | 2008-02-08 | Uso de antagonistas de interleucina-23 para el tratamiento de infeccion. |
Country Status (13)
Country | Link |
---|---|
US (2) | US8586035B2 (es) |
EP (1) | EP2064246B1 (es) |
JP (2) | JP5320301B2 (es) |
CN (1) | CN101668775B (es) |
AU (1) | AU2008262544B2 (es) |
BR (1) | BRPI0807487A8 (es) |
CA (1) | CA2677835A1 (es) |
CL (1) | CL2008000418A1 (es) |
MX (1) | MX2009008617A (es) |
NZ (2) | NZ578955A (es) |
TW (1) | TWI426918B (es) |
WO (1) | WO2008153610A2 (es) |
ZA (1) | ZA200906126B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
WO2009108341A1 (en) * | 2008-02-28 | 2009-09-03 | Argos Therapeutics, Inc. | Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection |
US20110158992A1 (en) * | 2008-08-27 | 2011-06-30 | Schering Corporation | Engineered Anti-IL-23R Antibodies |
JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
EP2635601B1 (en) | 2010-11-04 | 2016-07-20 | Boehringer Ingelheim International GmbH | Anti-il-23 antibodies |
US20130302343A1 (en) * | 2011-01-04 | 2013-11-14 | Charité Universitätsmedizin Berlin | Modulators of il-12 and/or il-23 for the prevention or treatment of alzheimer's disease |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
CN103826627B (zh) | 2011-10-21 | 2016-02-24 | 艾伯维公司 | 包含至少两种直接抗病毒剂和利巴韦林的组合物在制备治疗hcv的药物中的用途 |
WO2013059638A1 (en) | 2011-10-21 | 2013-04-25 | Abbvie Inc. | Combination treatment (eg. with abt-072 or abt -333) of daas for use in treating hcv |
PL3326649T3 (pl) | 2012-05-03 | 2022-04-25 | Boehringer Ingelheim International Gmbh | Przeciwciała anty-il-23p19 |
US9803010B2 (en) | 2012-06-27 | 2017-10-31 | Merck Sharp & Dohme Corp. | Crystalline anti-human IL-23p19 antibodies |
UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
WO2015157561A1 (en) * | 2014-04-09 | 2015-10-15 | La Jolla Institute For Allergy And Immunology | Specific and unique t cell responses and molecular signatures for treatment and diagnosis of mycobacterium tuberculosis |
JP2017524359A (ja) | 2014-07-24 | 2017-08-31 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Il−23a関連疾患の処置に有用なバイオマーカー |
SG11201701423RA (en) | 2014-09-03 | 2017-03-30 | Boehringer Ingelheim Int | Compound targeting il-23a and tnf-alpha and uses thereof |
CN105420238A (zh) * | 2015-09-08 | 2016-03-23 | 中国农业科学院兰州兽医研究所 | 靶向抑制小鼠白细胞介素17A基因的序列siRNA-136 |
JP7129703B2 (ja) | 2016-04-28 | 2022-09-02 | エモリー ユニバーシティー | アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用 |
EP3534910A4 (en) | 2016-10-04 | 2020-11-25 | Pop Test Oncology LLC | THERAPEUTICS AND PROCEDURES |
JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
CN110913906A (zh) | 2017-05-02 | 2020-03-24 | 默沙东公司 | 抗lag3抗体的制剂和抗lag3抗体与抗pd-1抗体的共制剂 |
EP3634405A4 (en) * | 2017-05-12 | 2021-06-09 | The Regents of The University of California | METHODS OF DETECTING DYSBIOSIS AND TREATING PATIENTS WITH DYSBIOSIS |
CN108743603B (zh) * | 2018-06-22 | 2020-06-30 | 山东省千佛山医院 | 利巴韦林单用或联合氟康唑的抗真菌产品及其应用 |
WO2020096058A1 (ja) * | 2018-11-09 | 2020-05-14 | 学校法人立命館 | 皮脂腺調整剤 |
CN112500490B (zh) * | 2020-10-14 | 2022-05-03 | 华南农业大学 | 一种抗左旋氧氟沙星抗体的F(ab)2片段及其制备方法和应用 |
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US4144346A (en) | 1977-01-31 | 1979-03-13 | Janssen Pharmaceutica N.V. | Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles |
US4218458A (en) | 1978-06-23 | 1980-08-19 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
DE3262386D1 (en) | 1981-06-06 | 1985-03-28 | Pfizer Ltd | Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them |
ATE248625T1 (de) * | 1996-09-12 | 2003-09-15 | Merck & Co Inc | Fungizide kombinationstherapie |
PE20000183A1 (es) | 1997-07-25 | 2000-03-11 | Schering Corp | Citoquinas de mamiferos y reactivos relacionados |
US6492497B1 (en) * | 1999-04-30 | 2002-12-10 | Cambridge Antibody Technology Limited | Specific binding members for TGFbeta1 |
EP1181366B2 (en) | 1999-06-01 | 2013-08-21 | Merck Sharp & Dohme Corp. | Mammalian receptor proteins; related reagents and methods |
HU230679B1 (en) | 1999-09-09 | 2017-08-28 | Merck Sharp & Dohme | Mammalian interleukin-12 p40 and interleukin b30, combinations thereof, antibodies, uses in pharmaceutical compositions |
ES2307618T3 (es) | 2000-05-10 | 2008-12-01 | Schering Corporation | Proteinas subunidades de receptores de cotocinas de mamiferos, reactivos y metodos relacionados. |
AUPR381601A0 (en) * | 2001-03-19 | 2001-04-12 | Monash University | Method of treating respiratory conditions |
EP1418936A2 (en) * | 2001-05-09 | 2004-05-19 | Alk-Abell A/S | Pharmaceutical compositions for preventing or treating th1 and th2 cell related diseases by modulating the th1/th2 ratio. |
KR101053412B1 (ko) * | 2002-10-30 | 2011-08-01 | 제넨테크, 인크. | Il―17 생성의 억제 |
US7282204B2 (en) * | 2003-03-10 | 2007-10-16 | Schering Corporation | Uses of IL-23 agonists and antagonists; related reagents |
AU2004229527B2 (en) * | 2003-04-11 | 2009-08-20 | Medimmune, Llc | Methods of preventing or treating respiratory conditions |
CA2525184C (en) * | 2003-05-09 | 2012-10-30 | Centocor, Inc. | Il-23p40 specific immunoglobulin derived proteins, compositions, methods and uses |
SI2784084T2 (sl) * | 2003-07-08 | 2024-02-29 | Novartis Pharma Ag | Antagonistična protitelesa proti IL-17 A/F heterolognim polipeptidom |
GB0329146D0 (en) | 2003-12-16 | 2004-01-21 | Glaxosmithkline Biolog Sa | Vaccine |
EP1901768B1 (en) * | 2004-02-17 | 2011-11-16 | Schering Corporation | Methods of modulating il-23 activity; related reagents |
US20060193821A1 (en) | 2004-03-05 | 2006-08-31 | Diener John L | Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics |
GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
AR051444A1 (es) | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
GB0425569D0 (en) | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Biological products |
GB0507561D0 (en) | 2005-04-14 | 2005-05-18 | Trinity College Dublin | Modulation of an immune response by filamentous haemagglutinin |
HUE042561T2 (hu) * | 2005-06-30 | 2019-07-29 | Janssen Biotech Inc | Anti-IL-23-ellenanyagok, készítmények, eljárások és alkalmazások |
DK1937721T3 (da) * | 2005-08-25 | 2010-10-18 | Lilly Co Eli | Anti-IL-23 antistoffer |
SG165322A1 (en) | 2005-08-31 | 2010-10-28 | Schering Corp | Engineered anti-il-23 antibodies |
ES2517420T3 (es) | 2005-12-29 | 2014-11-03 | Janssen Biotech, Inc. | Anticuerpos anti-IL-23 humanos, composiciones, procedimientos y usos |
US7790862B2 (en) | 2006-06-13 | 2010-09-07 | Zymogenetics, Inc. | IL-17 and IL-23 antagonists and methods of using the same |
WO2008021156A2 (en) | 2006-08-11 | 2008-02-21 | Schering Corporation | Antibodies to il-17a |
TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
CN101663320A (zh) | 2007-02-23 | 2010-03-03 | 先灵公司 | 工程改造的抗IL-23p19抗体 |
KR101520110B1 (ko) | 2007-02-23 | 2015-05-18 | 머크 샤프 앤드 돔 코포레이션 | 가공된 항-IL-23p19 항체 |
CA2679381A1 (en) | 2007-02-28 | 2008-09-04 | Schering Corporation | Engineered anti-il-23r antibodies |
US20110158992A1 (en) | 2008-08-27 | 2011-06-30 | Schering Corporation | Engineered Anti-IL-23R Antibodies |
-
2008
- 2008-02-05 TW TW097104700A patent/TWI426918B/zh not_active IP Right Cessation
- 2008-02-08 MX MX2009008617A patent/MX2009008617A/es active IP Right Grant
- 2008-02-08 EP EP08714214.7A patent/EP2064246B1/en active Active
- 2008-02-08 WO PCT/US2008/001717 patent/WO2008153610A2/en active Application Filing
- 2008-02-08 AU AU2008262544A patent/AU2008262544B2/en not_active Ceased
- 2008-02-08 CN CN200880010208.4A patent/CN101668775B/zh not_active Expired - Fee Related
- 2008-02-08 CA CA002677835A patent/CA2677835A1/en not_active Abandoned
- 2008-02-08 NZ NZ578955A patent/NZ578955A/en not_active IP Right Cessation
- 2008-02-08 JP JP2009549119A patent/JP5320301B2/ja not_active Expired - Fee Related
- 2008-02-08 NZ NZ599827A patent/NZ599827A/xx not_active IP Right Cessation
- 2008-02-08 US US12/525,003 patent/US8586035B2/en not_active Expired - Fee Related
- 2008-02-08 CL CL2008000418A patent/CL2008000418A1/es unknown
- 2008-02-08 BR BRPI0807487A patent/BRPI0807487A8/pt not_active IP Right Cessation
-
2009
- 2009-09-03 ZA ZA200906126A patent/ZA200906126B/xx unknown
-
2012
- 2012-10-18 JP JP2012230578A patent/JP2013014624A/ja active Pending
-
2013
- 2013-10-28 US US14/065,171 patent/US20140147442A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2064246B1 (en) | 2013-05-22 |
WO2008153610A2 (en) | 2008-12-18 |
BRPI0807487A2 (pt) | 2015-09-01 |
JP2013014624A (ja) | 2013-01-24 |
JP2010518087A (ja) | 2010-05-27 |
US8586035B2 (en) | 2013-11-19 |
EP2064246A2 (en) | 2009-06-03 |
CA2677835A1 (en) | 2008-12-18 |
CL2008000418A1 (es) | 2008-11-14 |
NZ599827A (en) | 2013-11-29 |
TWI426918B (zh) | 2014-02-21 |
TW200902062A (en) | 2009-01-16 |
US20140147442A1 (en) | 2014-05-29 |
CN101668775B (zh) | 2014-05-07 |
AU2008262544A1 (en) | 2008-12-18 |
US20100291084A1 (en) | 2010-11-18 |
JP5320301B2 (ja) | 2013-10-23 |
BRPI0807487A8 (pt) | 2016-02-10 |
NZ578955A (en) | 2012-06-29 |
CN101668775A (zh) | 2010-03-10 |
ZA200906126B (en) | 2010-06-30 |
AU2008262544B2 (en) | 2014-01-16 |
WO2008153610A3 (en) | 2009-03-19 |
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Owner name: EMERGENT PRODUCT DEVELOPMENT SEATTLE, LLC |
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