MX2009003794A - Composicion de prostaglandina e estabilizada. - Google Patents
Composicion de prostaglandina e estabilizada.Info
- Publication number
- MX2009003794A MX2009003794A MX2009003794A MX2009003794A MX2009003794A MX 2009003794 A MX2009003794 A MX 2009003794A MX 2009003794 A MX2009003794 A MX 2009003794A MX 2009003794 A MX2009003794 A MX 2009003794A MX 2009003794 A MX2009003794 A MX 2009003794A
- Authority
- MX
- Mexico
- Prior art keywords
- prostaglandin
- composition
- alkyl
- carboxylic ester
- alcohols
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición de prostaglandina E sustancialmente libre de alcoholes (C1-C4) e incluye el compuesto de prostaglandina E junto con un éster carboxílico (C1-C4)-alquilo (C8-C22) (por ejemplo, laurato de etilo), un alquilamino N,N-di(C1-C9) sustituido, éster carboxílico (C4-C18) alquilo (C2-C18) y/o una sal de adición farmacéuticamente aceptable de las mismas y, de manera opcional, un agente que intensifica la viscosidad tal como goma guar. La composición de la prostaglandina E puede ser combinada con un diluyente alcohólico acuoso para formar una composición farmacéutica para aplicación tópica a un paciente, por ejemplo, para tratar disfunción sexual. Las composiciones de prostaglandina E son estables durante periodos prolongados de almacenamiento a temperatura ambiente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/546,196 US7560489B2 (en) | 2006-10-11 | 2006-10-11 | Stabilized prostaglandin E composition |
PCT/US2007/021374 WO2008045309A1 (en) | 2006-10-11 | 2007-10-05 | Stabilized prostaglandin e composition |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009003794A true MX2009003794A (es) | 2009-04-24 |
Family
ID=39283156
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009003794A MX2009003794A (es) | 2006-10-11 | 2007-10-05 | Composicion de prostaglandina e estabilizada. |
Country Status (12)
Country | Link |
---|---|
US (1) | US7560489B2 (es) |
EP (1) | EP2073634A4 (es) |
JP (1) | JP5382800B2 (es) |
KR (1) | KR101400359B1 (es) |
AU (1) | AU2007307136B2 (es) |
BR (1) | BRPI0719228A2 (es) |
CA (1) | CA2665611C (es) |
IL (1) | IL197885A (es) |
MX (1) | MX2009003794A (es) |
NZ (1) | NZ576242A (es) |
WO (1) | WO2008045309A1 (es) |
ZA (1) | ZA200902467B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7560489B2 (en) * | 2006-10-11 | 2009-07-14 | Nexmed Holdings, Inc. | Stabilized prostaglandin E composition |
NZ592300A (en) | 2008-10-03 | 2013-01-25 | Nexmed Holdings Inc | Stabilized composition for treating psoriasis |
ES2921527T3 (es) | 2009-06-03 | 2022-08-29 | Forsight Vision5 Inc | Administración de fármaco en segmento anterior |
RU2012153177A (ru) | 2010-05-04 | 2014-06-20 | Нексмед Холдингс, Инк. | Композиции низкомолекулярных терапевтических средств |
CA2797966A1 (en) * | 2010-05-04 | 2011-11-10 | Nexmed Holdings, Inc. | Therapeutic peptide composition and method |
CA2745320A1 (en) | 2011-07-06 | 2013-01-06 | Duoject Medical Systems Inc. | Reconstitution device |
RU2740680C2 (ru) | 2011-09-14 | 2021-01-19 | Форсайт Вижн5, Инк. | Глазное вкладочное устройство и способы |
CN104884006B (zh) | 2012-10-26 | 2017-12-15 | 弗赛特影像5股份有限公司 | 用于持续释放药物到眼睛的眼科*** |
WO2016168141A1 (en) | 2015-04-13 | 2016-10-20 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4036954A (en) * | 1973-11-02 | 1977-07-19 | Yamanouchi Pharmaceutical Co., Ltd. | Stable prostaglandin E group-containing formulation |
US4113882A (en) * | 1974-10-21 | 1978-09-12 | Yamanouchi Pharmaceutical Co., Ltd. | Stabilized oral prostaglandin formulation and the process for the preparation thereof |
JPS5770816A (en) * | 1980-10-17 | 1982-05-01 | Ono Pharmaceut Co Ltd | Multilayered film preparation of prostagladin of prolonged action |
JPS58134019A (ja) * | 1982-02-05 | 1983-08-10 | Ono Pharmaceut Co Ltd | プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法 |
US4806354A (en) * | 1984-04-06 | 1989-02-21 | Green James P | Health food composition |
US5525348A (en) * | 1989-11-02 | 1996-06-11 | Sts Biopolymers, Inc. | Coating compositions comprising pharmaceutical agents |
CA2071137A1 (en) * | 1991-07-10 | 1993-01-11 | Clarence C. Lee | Composition and method for revitalizing scar tissue |
US6414028B1 (en) * | 1997-11-05 | 2002-07-02 | Nexmed Holdings, Inc. | Topical compositions containing prostaglandin E1 |
US6046244A (en) * | 1997-11-05 | 2000-04-04 | Nexmed Holdings, Inc. | Topical compositions for prostaglandin E1 delivery |
US5942545A (en) * | 1998-06-15 | 1999-08-24 | Macrochem Corporation | Composition and method for treating penile erectile dysfunction |
US6825234B2 (en) * | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
US6693135B2 (en) * | 2000-01-10 | 2004-02-17 | Nexmed (Holdings) Incorporated | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
US20040110843A1 (en) * | 2000-01-10 | 2004-06-10 | Nexmed (Holdings), Inc. | Methods of treatment of male erectile dysfunction |
GB2372213B (en) * | 2000-11-17 | 2003-07-16 | Icebella Enterpises Ltd | Applicator and stimulator device |
US6841574B2 (en) * | 2003-01-03 | 2005-01-11 | Nexmed Holdings, Inc. | Topical stabilized prostaglandin E compound dosage forms |
US20050181030A1 (en) * | 2003-01-03 | 2005-08-18 | Mo Y. J. | Topical stabilized prostaglandin E compound dosage forms |
EP1462098B1 (en) * | 2003-03-03 | 2007-07-04 | SPRL Franpharma | Stabilised pharmaceutical composition comprising a non-steroidal anti-inflammatory agent and a prostaglandin |
AR043476A1 (es) * | 2004-09-09 | 2005-08-03 | Dvoskin Victor Oscar | Dispositivo de administracion regulada de sustancias para la insercion en una cavidad corporal y procedimiento para fabricar un medio de soporte de dichas sustancias |
US7560489B2 (en) * | 2006-10-11 | 2009-07-14 | Nexmed Holdings, Inc. | Stabilized prostaglandin E composition |
-
2006
- 2006-10-11 US US11/546,196 patent/US7560489B2/en active Active
-
2007
- 2007-10-05 EP EP07839278A patent/EP2073634A4/en not_active Withdrawn
- 2007-10-05 MX MX2009003794A patent/MX2009003794A/es active IP Right Grant
- 2007-10-05 BR BRPI0719228-2A2A patent/BRPI0719228A2/pt not_active Application Discontinuation
- 2007-10-05 AU AU2007307136A patent/AU2007307136B2/en not_active Ceased
- 2007-10-05 KR KR1020097008945A patent/KR101400359B1/ko not_active IP Right Cessation
- 2007-10-05 NZ NZ576242A patent/NZ576242A/en not_active IP Right Cessation
- 2007-10-05 JP JP2009532364A patent/JP5382800B2/ja not_active Expired - Fee Related
- 2007-10-05 CA CA2665611A patent/CA2665611C/en not_active Expired - Fee Related
- 2007-10-05 WO PCT/US2007/021374 patent/WO2008045309A1/en active Application Filing
-
2009
- 2009-04-05 IL IL197885A patent/IL197885A/en not_active IP Right Cessation
- 2009-04-08 ZA ZA200902467A patent/ZA200902467B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200902467B (en) | 2010-03-31 |
BRPI0719228A2 (pt) | 2015-02-03 |
WO2008045309A1 (en) | 2008-04-17 |
KR101400359B1 (ko) | 2014-06-19 |
IL197885A (en) | 2016-04-21 |
JP5382800B2 (ja) | 2014-01-08 |
CA2665611A1 (en) | 2008-04-17 |
US20080090911A1 (en) | 2008-04-17 |
US7560489B2 (en) | 2009-07-14 |
AU2007307136B2 (en) | 2013-12-05 |
EP2073634A4 (en) | 2012-12-19 |
AU2007307136A1 (en) | 2008-04-17 |
NZ576242A (en) | 2012-04-27 |
KR20090064597A (ko) | 2009-06-19 |
EP2073634A1 (en) | 2009-07-01 |
JP2010506831A (ja) | 2010-03-04 |
IL197885A0 (en) | 2009-12-24 |
CA2665611C (en) | 2014-11-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2009003794A (es) | Composicion de prostaglandina e estabilizada. | |
CA2757418C (en) | Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same | |
MX2011012627A (es) | Derivados aminobutiricos sustituidos como inhibidores de nepralisina. | |
MX2011010415A (es) | Formulaciones farmaceuticas que comprenden derivados de nitrocatecol y metodos para hacer las mismas. | |
BR112012018384A2 (pt) | composição farmacêutica sólida com intensificadores e métodos de preparação da mesma. | |
MA33768B1 (fr) | Triazolopyridines | |
WO2008030744A3 (en) | Inhibitors of c-met and uses thereof | |
IN2014CN02592A (es) | ||
UA94606C2 (ru) | Производные тиоксантина, композиция, которая их содержит, и их применение в терапии | |
MX2011012628A (es) | Derivados amino-propionicos sustituidos como inhibidores de neprilisina. | |
WO2007145991A3 (en) | Anti-inflammatory and analgesic compositions and related methods | |
WO2007137066A3 (en) | HETEROCYCLIC INHIBITORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE I AND METHODS OF USING THE SAME | |
WO2012071389A3 (en) | Stable cannabinoid compositions and methods for making and storing them | |
GEP20135744B (en) | Quinuclidine carbonate derivatives and medicinal compositions containing the same | |
PE20130236A1 (es) | Composicion farmaceutica que comprende un derivado de amida o una sal farmaceuticamente aceptable del mismo | |
NZ714558A (en) | Formulation comprising a hypolipidemic agent | |
MX2020008173A (es) | Combinacion de un agente antimuscarinico o de uno anticolinergico y acido lipoico, y sus usos. | |
RU2011138962A (ru) | Производные 4-изопропилфенилглюцита в качестве ингибиторов sglt1 | |
UA109421C2 (uk) | Фармацевтична композиція, яка містить ліганди сигма-рецептора | |
MY155938A (en) | Oral pharmaceutical composition | |
TN2013000257A1 (en) | Immunosuppressant formulations | |
BR112013030939A2 (pt) | derivado de indazol e pirrolopiridina e uso farmacêutico do mesmo | |
WO2009007137A3 (en) | Pharmaceutical composition for topical application of poorly soluble compounds | |
NZ603108A (en) | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators | |
PH12015500864A1 (en) | Liquid formulation comprising gm-csf neutralizing compound |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |