MX2009002054A - Metodos para inhibir angiogenesis y tratamiento contra enfermedades asociadas con angiogenesis. - Google Patents
Metodos para inhibir angiogenesis y tratamiento contra enfermedades asociadas con angiogenesis.Info
- Publication number
- MX2009002054A MX2009002054A MX2009002054A MX2009002054A MX2009002054A MX 2009002054 A MX2009002054 A MX 2009002054A MX 2009002054 A MX2009002054 A MX 2009002054A MX 2009002054 A MX2009002054 A MX 2009002054A MX 2009002054 A MX2009002054 A MX 2009002054A
- Authority
- MX
- Mexico
- Prior art keywords
- angiogenesis
- associated diseases
- methods
- treating
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
La invención proporciona métodos para inhibir la angiogénesis en un individuo mediante la administración de una composición (como una proteína contenida en la composición) que comprende el dímero de colchicina o tiocolchicina. La composición está presente en una cantidad efectiva para la inhibición de angiogénesis, pero en algunas modalidades es insuficiente para inducir una citotoxicidad significativa en el individuo. Los métodos descritos aquí son útiles para el tratamiento contra enfermedades asociadas con la angiogénesis, como degeneración macular relacionada con la edad, retinopatía diabética, artritis reumática, psoriasis y cáncer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2006/034365 WO2008027055A1 (en) | 2006-08-31 | 2006-08-31 | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009002054A true MX2009002054A (es) | 2009-05-01 |
Family
ID=37763804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009002054A MX2009002054A (es) | 2006-08-31 | 2006-08-31 | Metodos para inhibir angiogenesis y tratamiento contra enfermedades asociadas con angiogenesis. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2056812A1 (es) |
JP (1) | JP2010502603A (es) |
CN (1) | CN101568332A (es) |
AU (1) | AU2006347740A1 (es) |
BR (1) | BRPI0622006A2 (es) |
CA (1) | CA2662140A1 (es) |
IL (1) | IL197276A0 (es) |
MX (1) | MX2009002054A (es) |
WO (1) | WO2008027055A1 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
CN101291659A (zh) | 2005-08-31 | 2008-10-22 | 阿布拉科斯生物科学有限公司 | 包含水难溶性药剂和抗微生物剂的组合物 |
JP5933893B2 (ja) | 2006-12-14 | 2016-06-15 | アブラクシス バイオサイエンス, エルエルシー | ホルモン受容体状態に基づいてタキサンを含むナノ粒子用いる乳癌治療法 |
PL2131821T3 (pl) | 2007-03-07 | 2018-11-30 | Abraxis Bioscience, Llc | Nanocząstka zawierająca rapamycynę i albuminę jako środek przeciwnowotworowy |
JP5579057B2 (ja) | 2007-06-01 | 2014-08-27 | アブラクシス バイオサイエンス, エルエルシー | 再発性癌の処置のための方法および組成物 |
US8821870B2 (en) * | 2008-07-18 | 2014-09-02 | Allergan, Inc. | Method for treating atrophic age related macular degeneration |
TW201012473A (en) * | 2008-09-22 | 2010-04-01 | Tty Biopharm Co Ltd | Composition of inhibiting pathological angiogenesis |
MY175260A (en) | 2009-04-15 | 2020-06-17 | Abraxis Bioscience Llc | Prion free nanoparticle compositions and methods of making thereof |
EP2515930A4 (en) * | 2009-12-21 | 2013-04-10 | Tty Biopharm Co Ltd | METHODS AND COMPOSITIONS BASED ON REDUCED MET PHOSPHORYLATION BY CHEMOTAXIN 2 DERIVED FROM LEUKOCYTE CELLS IN TUMOR CELLS |
BR112012024349A2 (pt) | 2010-03-26 | 2016-05-24 | Abraxis Bioscience Llc | métodos de tratamento de carcinoma hepatocelular |
CN107158389A (zh) | 2010-03-29 | 2017-09-15 | 阿布拉科斯生物科学有限公司 | 增强药物递送和治疗剂有效性的方法 |
NZ602385A (en) | 2010-03-29 | 2014-08-29 | Abraxis Bioscience Llc | Methods of treating cancer |
WO2011153010A1 (en) | 2010-06-04 | 2011-12-08 | Abraxis Biosciences, Llc | Methods of treatment of pancreatic cancer |
JP6031718B2 (ja) * | 2011-09-20 | 2016-11-30 | 国立大学法人 熊本大学 | リポ蛋白を用いたα2−マクログロブリンの神経保護抑制効果抑止剤及び眼科用組成物 |
ES2746057T3 (es) | 2011-12-14 | 2020-03-04 | Abraxis Bioscience Llc | Uso de excipientes poliméricos para liofilización o congelación de partículas |
US9149455B2 (en) | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
CN105228612A (zh) | 2013-03-12 | 2016-01-06 | 阿布拉科斯生物科学有限公司 | 治疗肺癌的方法 |
AU2014236802B2 (en) | 2013-03-14 | 2019-01-03 | Abraxis Bioscience, Llc | Methods of treating bladder cancer |
EP2924022A1 (en) * | 2014-03-27 | 2015-09-30 | INDENA S.p.A. | Amorphous form of a thiocolchicine derivative |
US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
JP6987644B2 (ja) | 2015-06-29 | 2022-01-05 | アブラクシス バイオサイエンス, エルエルシー | 類上皮細胞腫瘍を処置する方法 |
AU2019239953A1 (en) | 2018-03-20 | 2020-10-15 | Abraxis Bioscience, Llc | Methods of treating central nervous system disorders via administration of nanoparticles of an mtor inhibitor and an albumin |
EP4051241A4 (en) | 2019-10-28 | 2023-12-06 | Abraxis BioScience, LLC | PHARMACEUTICAL COMPOSITIONS OF ALBUMIN AND RAPAMYCIN |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1318401B1 (it) * | 2000-03-17 | 2003-08-25 | Indena Spa | Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono. |
ES2685436T3 (es) * | 2002-12-09 | 2018-10-09 | Abraxis Bioscience, Llc | Composiciones y procedimientos para administración de agentes farmacológicos |
KR20180098702A (ko) * | 2002-12-09 | 2018-09-04 | 아브락시스 바이오사이언스, 엘엘씨 | 약리학적 물질의 조성물 및 그 전달방법 |
US6825236B2 (en) * | 2003-04-14 | 2004-11-30 | California Pacific Medical Center | Colchicine derivatives |
ITMI20040164A1 (it) * | 2004-02-03 | 2004-05-03 | Indena Spa | Derivati di n.deacetiltiocolchicina loro uso e formulazioni farmaceutiche che li contengono |
CA3054535A1 (en) * | 2005-02-18 | 2006-08-24 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
-
2006
- 2006-08-31 JP JP2009526583A patent/JP2010502603A/ja active Pending
- 2006-08-31 CN CNA2006800561122A patent/CN101568332A/zh active Pending
- 2006-08-31 MX MX2009002054A patent/MX2009002054A/es not_active Application Discontinuation
- 2006-08-31 BR BRPI0622006-1A patent/BRPI0622006A2/pt not_active Application Discontinuation
- 2006-08-31 EP EP06802881A patent/EP2056812A1/en not_active Withdrawn
- 2006-08-31 AU AU2006347740A patent/AU2006347740A1/en not_active Abandoned
- 2006-08-31 CA CA002662140A patent/CA2662140A1/en not_active Abandoned
- 2006-08-31 WO PCT/US2006/034365 patent/WO2008027055A1/en active Application Filing
-
2009
- 2009-02-26 IL IL197276A patent/IL197276A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2010502603A (ja) | 2010-01-28 |
CA2662140A1 (en) | 2008-03-06 |
CN101568332A (zh) | 2009-10-28 |
AU2006347740A1 (en) | 2008-03-06 |
EP2056812A1 (en) | 2009-05-13 |
WO2008027055A1 (en) | 2008-03-06 |
BRPI0622006A2 (pt) | 2011-12-20 |
IL197276A0 (en) | 2009-12-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2009002054A (es) | Metodos para inhibir angiogenesis y tratamiento contra enfermedades asociadas con angiogenesis. | |
MY155961A (en) | Chemical compounds 251 | |
MY155649A (en) | Pyridyloxyindoles inhibitors of vegf-r2 and use thereof for treatment of disease | |
TW200626576A (en) | Bicyclic amides as kinase inhibitors | |
CY1116156T1 (el) | Παραγωγα πυριμιδινης συνδεδεμενα με οξυγονο | |
BR112012009376A2 (pt) | composição farmacêutica, forma de dosagem farmacêutica, processo para a sua preparação, métodos de tratamento e seu uso | |
BRPI0809164B8 (pt) | Composição para administração tópica e composição farmacêutica compreendendo a referida composição | |
MX337575B (es) | Compuestos de sulfona y métodos para lafabricación y uso de éstos. | |
IN2012DN02018A (es) | ||
BR112012012918A2 (pt) | agente indutor de apoptose para o tratamento de câncer e de doenças imunes e autoimunes. | |
EA201690265A2 (ru) | Фармацевтические композиции, содержащие замещенные ациланилиды | |
GT200800184A (es) | Aminotetrahidropiranos como inhibidores de dipeptidil peptidasa-iv para el tratamiento o prevencion de diabetes. | |
IN2014MN00139A (es) | ||
MX345535B (es) | Compuestos tricíclicos parcialmente saturados y métodos para su fabricación y su uso. | |
MX347225B (es) | Metodos de tratamiento contra el cancer pancreatico. | |
ATE401088T1 (de) | Zusammensetzung mit einem survivin-antisense- oligonucleotid und gemcitabin zur behandlung von krebs | |
CY1115082T1 (el) | Υποκατεστημενα παραγωγα 1,3-διφαινυλπροπανιου, παρασκευες και χρησεις αυτων | |
CL2010001260A1 (es) | Composicion farmaceutica que comprende una sal de estroncio y vitamina d y una ciclodextrina, donde la relacion masica entre la cantidad de vitamina d y la cantidad de ciclodextrina esta comprendida entre 1/40 y 1/800, util para tratar o prevenir osteoporosis. | |
CR10099A (es) | Inmunoglobulinas dirigidas contra nogo | |
BRPI0507482A (pt) | combinação de (a) um inibidor de dna topoisomerase e (b) um inibidor de iap | |
UY29161A1 (es) | Nuevos heterociclos | |
MY148893A (en) | Combination of an hdac inhibitor and an antimetabolite | |
CY1116234T1 (el) | Υποκατεστημενα 2-οξυ-κινολινο-3-καρβοξαμιδια σαν διαμορφωτες kcnq2/3 | |
TW200740808A (en) | Inhibiteurs de proteines kinases | |
CR20240003A (es) | Restos de administración terapéutica novedosos y usos de estos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |