MX2007015471A - Amilasas para uso farmaceutico. - Google Patents

Amilasas para uso farmaceutico.

Info

Publication number
MX2007015471A
MX2007015471A MX2007015471A MX2007015471A MX2007015471A MX 2007015471 A MX2007015471 A MX 2007015471A MX 2007015471 A MX2007015471 A MX 2007015471A MX 2007015471 A MX2007015471 A MX 2007015471A MX 2007015471 A MX2007015471 A MX 2007015471A
Authority
MX
Mexico
Prior art keywords
amylases
bacillus
improved
pharmaceutical use
seq
Prior art date
Application number
MX2007015471A
Other languages
English (en)
Inventor
Allan Svendsen
Peter Colin Gregory
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Publication of MX2007015471A publication Critical patent/MX2007015471A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

El uso farmaceutico de amilasas relacionadas con alfa amilasas de Bacillus de las SEQ ID NOs: 1-3, opcionalmente en combinacion con una lipasa y/o una proteasa. Los ejemplos de indicaciones medicas son: Tratamiento de trastornos digestivos, insuficiencia exocrina pancreatica (PEI), pancreatitis, fibrosis quistica, diabetes tipo I, y/o diabetes tipo II. Las amilasas de las SEQ ID NOs: 1-3 son variantes de las amilasas de Bacillus stearothermophilus, Bacilus licheniformis y Bacillus sp. Las amilasas de la invencion tienen una mejor eficacia in vivo, un mejor perfil de pH, una alta actividad especifica, y/o mejor perfil de degradacion de almidon.
MX2007015471A 2005-06-24 2006-06-16 Amilasas para uso farmaceutico. MX2007015471A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500931 2005-06-24
PCT/DK2006/000354 WO2006136161A2 (en) 2005-06-24 2006-06-16 Amylases for pharmaceutical use

Publications (1)

Publication Number Publication Date
MX2007015471A true MX2007015471A (es) 2008-04-04

Family

ID=34956782

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007015471A MX2007015471A (es) 2005-06-24 2006-06-16 Amilasas para uso farmaceutico.

Country Status (15)

Country Link
US (1) US8017351B2 (es)
EP (1) EP1896057A2 (es)
JP (1) JP2008546396A (es)
KR (1) KR20080031868A (es)
CN (1) CN101242853A (es)
AU (1) AU2006261444A1 (es)
BR (1) BRPI0611932A2 (es)
CA (1) CA2612811A1 (es)
IL (1) IL187635A0 (es)
MX (1) MX2007015471A (es)
NO (1) NO20080439L (es)
NZ (1) NZ563737A (es)
RU (1) RU2008102650A (es)
WO (1) WO2006136161A2 (es)
ZA (1) ZA200710644B (es)

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Also Published As

Publication number Publication date
RU2008102650A (ru) 2009-07-27
CA2612811A1 (en) 2006-12-28
IL187635A0 (en) 2008-03-20
US8017351B2 (en) 2011-09-13
US20090035293A1 (en) 2009-02-05
WO2006136161A2 (en) 2006-12-28
AU2006261444A1 (en) 2006-12-28
WO2006136161A3 (en) 2007-07-05
NO20080439L (no) 2008-03-04
BRPI0611932A2 (pt) 2011-01-04
EP1896057A2 (en) 2008-03-12
KR20080031868A (ko) 2008-04-11
CN101242853A (zh) 2008-08-13
NZ563737A (en) 2010-08-27
JP2008546396A (ja) 2008-12-25
ZA200710644B (en) 2008-11-26

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