MX2007006373A - Regimen de dosificacion de un agonista del receptor s1p. - Google Patents

Regimen de dosificacion de un agonista del receptor s1p.

Info

Publication number
MX2007006373A
MX2007006373A MX2007006373A MX2007006373A MX2007006373A MX 2007006373 A MX2007006373 A MX 2007006373A MX 2007006373 A MX2007006373 A MX 2007006373A MX 2007006373 A MX2007006373 A MX 2007006373A MX 2007006373 A MX2007006373 A MX 2007006373A
Authority
MX
Mexico
Prior art keywords
daily dosage
dosage regimen
receptor agonist
dosage
standard
Prior art date
Application number
MX2007006373A
Other languages
English (en)
Inventor
John M Kovarik
Silke Appel-Dingemanse
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36046868&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2007006373(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2007006373A publication Critical patent/MX2007006373A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Storage Device Security (AREA)

Abstract

Se administran moduladores o agonistas de receptor S1P siguiente a un regimen de dosificacion por el que durante los 3 a 6 dias iniciales de tratamiento la dosificacion diaria se eleva de manera que se administra en total R veces (siendo R el factor de acumulacion) la dosificacion diaria estandar y despues se continua en la dosificacion diaria estandar o a una dosificacion diaria menor que la dosificacion diaria estandar.
MX2007006373A 2004-11-29 2005-11-28 Regimen de dosificacion de un agonista del receptor s1p. MX2007006373A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63148304P 2004-11-29 2004-11-29
PCT/US2005/043044 WO2006058316A1 (en) 2004-11-29 2005-11-28 Dosage regimen of an s1p receptor agonist

Publications (1)

Publication Number Publication Date
MX2007006373A true MX2007006373A (es) 2007-06-20

Family

ID=36046868

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006373A MX2007006373A (es) 2004-11-29 2005-11-28 Regimen de dosificacion de un agonista del receptor s1p.

Country Status (22)

Country Link
US (3) US20090275553A1 (es)
EP (3) EP2359821A1 (es)
JP (4) JP2008521827A (es)
KR (4) KR20130041385A (es)
CN (2) CN102600472A (es)
AU (1) AU2005309378B2 (es)
BR (1) BRPI0518674A2 (es)
CA (1) CA2589265A1 (es)
ES (1) ES2495690T3 (es)
HK (1) HK1109057A1 (es)
IL (2) IL183134A0 (es)
MA (1) MA29034B1 (es)
MX (1) MX2007006373A (es)
NO (2) NO20072401L (es)
NZ (2) NZ554720A (es)
PL (1) PL1819326T3 (es)
PT (1) PT1819326E (es)
RU (2) RU2478384C2 (es)
SG (2) SG187468A1 (es)
TN (1) TNSN07209A1 (es)
WO (1) WO2006058316A1 (es)
ZA (1) ZA200703328B (es)

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KR20070058455A (ko) 2004-08-13 2007-06-08 프래시스 파마슈티컬즈 인코포레이티드 스핑고신-1-포스페이트(s1p) 수용체 활성을 조절하기위한 방법 및 조성물
RU2478384C2 (ru) * 2004-11-29 2013-04-10 Новартис Аг Курс лечения с использованием агониста рецептора s1p
RU2493840C2 (ru) * 2005-09-09 2013-09-27 Новартис Аг Лечение аутоиммунных заболеваний
GB0612721D0 (en) * 2006-06-27 2006-08-09 Novartis Ag Organic compounds
MX2009011943A (es) 2007-05-04 2009-11-13 Novartis Ag Uso de modulador de los receptores de la sip.
ES2617628T5 (es) 2008-03-17 2020-06-01 Actelion Pharmaceuticals Ltd Régimen de dosificación para un agonista selectivo del receptor de S1P1
JPWO2009142195A1 (ja) * 2008-05-20 2011-09-29 杏林製薬株式会社 寛解導入維持剤
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CN103271905A (zh) * 2008-08-18 2013-09-04 诺瓦提斯公司 用于治疗周围神经病的化合物
CN102256942B (zh) * 2008-12-18 2013-07-24 诺瓦提斯公司 1-(4-{1-[(e)-4-环己基-3-三氟甲基-苄氧基亚氨基]-乙基}-2-乙基-苄基)-氮杂环丁烷-3-甲酸的多晶型物
US8486930B2 (en) * 2008-12-18 2013-07-16 Novartis Ag Salts
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AR074825A1 (es) * 2008-12-22 2011-02-16 Novartis Ag Regimen de dosificacion de un agonista de los receptores de s1p, metodo de tratamiento y kit
AU2015275246B2 (en) * 2008-12-22 2018-02-01 Novartis Ag Dosage regimen for a S1P receptor agonist
LT3409274T (lt) * 2008-12-22 2020-02-10 Novartis Ag Dozavimo schema s1p receptoriaus agonistui
EP3061449A1 (en) * 2009-09-29 2016-08-31 Novartis AG Dosage regimen of an s1p receptor modulator
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WO2011138398A1 (en) * 2010-05-06 2011-11-10 Novartis Ag Dosage regimen of diaryl sulfide derivatives
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JP6322630B2 (ja) 2012-08-17 2018-05-09 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd (2Z,5Z)−5−(3−クロロ−4−((R)−2,3−ジヒドロキシプロポキシ)ベンジリデン)−2−(プロピルイミノ)−3−(o−トリル)チアゾリジン−4−オンの製造方法及び前記方法において使用される中間体
CN102887829B (zh) * 2012-09-05 2014-07-02 中国科学院上海药物研究所 芬戈莫德粘酸盐及其晶体的制备方法和用途
US10675254B2 (en) 2013-10-11 2020-06-09 Teikoku Seiyaku Co., Ltd. Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same
KR101820330B1 (ko) 2013-10-11 2018-01-19 테이코쿠 팔마 유에스에이, 인코포레이티드 국소 스핑고신-1-포스페이트 수용체 효현제 제형 및 이의 사용 방법
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Also Published As

Publication number Publication date
NO20072401L (no) 2007-06-22
JP2015061883A (ja) 2015-04-02
CN101068536A (zh) 2007-11-07
HK1109057A1 (en) 2008-05-30
EP1819326B1 (en) 2014-07-02
CN101068536B (zh) 2012-12-05
KR20140095109A (ko) 2014-07-31
ZA200703328B (en) 2008-08-27
US20120071446A1 (en) 2012-03-22
MA29034B1 (fr) 2007-11-01
RU2012141951A (ru) 2014-04-10
RU2478384C2 (ru) 2013-04-10
AU2005309378A1 (en) 2006-06-01
IL223502A0 (en) 2013-02-03
KR20150028858A (ko) 2015-03-16
RU2007124327A (ru) 2009-01-10
US20090275553A1 (en) 2009-11-05
EP2384749A1 (en) 2011-11-09
CN102600472A (zh) 2012-07-25
US20150087720A1 (en) 2015-03-26
JP2008521827A (ja) 2008-06-26
CA2589265A1 (en) 2006-06-01
PT1819326E (pt) 2014-09-25
AU2005309378B2 (en) 2010-02-11
NO20121305L (no) 2007-06-22
PL1819326T3 (pl) 2014-12-31
NZ590054A (en) 2012-07-27
SG187468A1 (en) 2013-02-28
KR20130041385A (ko) 2013-04-24
JP2013129664A (ja) 2013-07-04
NZ554720A (en) 2011-04-29
TNSN07209A1 (en) 2008-11-21
EP1819326A1 (en) 2007-08-22
KR20070085465A (ko) 2007-08-27
BRPI0518674A2 (pt) 2008-12-02
WO2006058316A1 (en) 2006-06-01
EP2359821A1 (en) 2011-08-24
IL183134A0 (en) 2008-04-13
ES2495690T3 (es) 2014-09-17
SG158096A1 (en) 2010-01-29
JP2012107059A (ja) 2012-06-07

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