MA54677A - Composés pyrazoles et leur préparation - Google Patents

Composés pyrazoles et leur préparation

Info

Publication number
MA54677A
MA54677A MA054677A MA54677A MA54677A MA 54677 A MA54677 A MA 54677A MA 054677 A MA054677 A MA 054677A MA 54677 A MA54677 A MA 54677A MA 54677 A MA54677 A MA 54677A
Authority
MA
Morocco
Prior art keywords
preparation
pyrazole compounds
pyrazole
compounds
Prior art date
Application number
MA054677A
Other languages
English (en)
Inventor
Rajdeep Anand
Priyanka Dhaka
Anurag Jain
Dinesh Jangid
Bharat Kumar
Kapil Kumar
Siddharth Madhwal
Sunil Sharma
Original Assignee
Myokardia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myokardia Inc filed Critical Myokardia Inc
Publication of MA54677A publication Critical patent/MA54677A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/72Copper
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J27/00Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • B01J27/06Halogens; Compounds thereof
    • B01J27/08Halides
    • B01J27/122Halides of copper
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
MA054677A 2018-02-01 2019-02-01 Composés pyrazoles et leur préparation MA54677A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201811003855 2018-02-01
IN201811003859 2018-02-01
IN201711042921 2018-05-30

Publications (1)

Publication Number Publication Date
MA54677A true MA54677A (fr) 2021-11-17

Family

ID=67478207

Family Applications (1)

Application Number Title Priority Date Filing Date
MA054677A MA54677A (fr) 2018-02-01 2019-02-01 Composés pyrazoles et leur préparation

Country Status (13)

Country Link
US (1) US11873289B2 (fr)
EP (1) EP3746434A4 (fr)
JP (1) JP7402804B2 (fr)
KR (1) KR20200118025A (fr)
CN (1) CN111670184A (fr)
AU (1) AU2019213854C1 (fr)
BR (1) BR112020015692A2 (fr)
CA (1) CA3090204A1 (fr)
IL (1) IL276410A (fr)
MA (1) MA54677A (fr)
MX (1) MX2020008151A (fr)
SG (1) SG11202007328UA (fr)
WO (1) WO2019150392A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3090204A1 (fr) 2018-02-01 2019-08-08 MyoKardia, Inc. Composes pyrazoles et leur preparation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007284386A (ja) 2006-04-18 2007-11-01 Kumiai Chem Ind Co Ltd 3−ピラゾリルフェニルスルフィド誘導体及びそれを有効成分として含有する殺虫・殺ダニ・殺線虫剤
US8324178B2 (en) 2008-10-31 2012-12-04 The Regents Of The University Of California Method of treatment using alpha-1-adrenergic agonist compounds
US9260416B2 (en) 2011-05-27 2016-02-16 Amira Pharmaceuticals, Inc. Heterocyclic autotaxin inhibitors and uses thereof
ES2588386T3 (es) 2012-08-30 2016-11-02 Bayer Cropscience Ag Procedimiento de descarboxilación de derivados de ácido 3,5-bis(haloalquil)-pirazol-4-carboxílico
WO2014089913A1 (fr) 2012-12-12 2014-06-19 山东亨利医药科技有限责任公司 Composé bicyclique fonctionnant en tant qu'inhibiteur de tyrosine kinase
WO2015063793A1 (fr) 2013-11-01 2015-05-07 Srf Limited Procédé de préparation de dérivés de pyrazole
EP3015458A1 (fr) 2014-11-03 2016-05-04 Bayer CropScience AG Procédé de préparation de dérivés de 3,5-bis bis(haloalkyl)pyrazole à partir de a,a-dihaloamines et ketimines
CN111393414B (zh) 2015-01-22 2024-05-07 迈奥卡迪亚公司 用于治疗扩张性心肌病(dcm)的4-甲基磺酰基取代的哌啶脲化合物
WO2018132372A1 (fr) * 2017-01-10 2018-07-19 Sanford Burnham Prebys Medical Discovery Institute Activateurs à petites molécules de nicotinamide phosphoribosyltransférase (nampt) et leurs utilisations
WO2018191283A1 (fr) * 2017-04-11 2018-10-18 Oric Pharmaceuticals, Inc. Modulateurs de récepteurs des glucocorticoïdes
CA3090204A1 (fr) 2018-02-01 2019-08-08 MyoKardia, Inc. Composes pyrazoles et leur preparation

Also Published As

Publication number Publication date
US20210053940A1 (en) 2021-02-25
CN111670184A (zh) 2020-09-15
KR20200118025A (ko) 2020-10-14
EP3746434A4 (fr) 2021-11-17
CA3090204A1 (fr) 2019-08-08
SG11202007328UA (en) 2020-08-28
US11873289B2 (en) 2024-01-16
AU2019213854C1 (en) 2023-12-14
AU2019213854B2 (en) 2023-06-15
AU2019213854A1 (en) 2020-09-03
IL276410A (en) 2020-09-30
MX2020008151A (es) 2020-09-18
JP7402804B2 (ja) 2023-12-21
BR112020015692A2 (pt) 2020-12-08
JP2021512127A (ja) 2021-05-13
WO2019150392A1 (fr) 2019-08-08
EP3746434A1 (fr) 2020-12-09

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