MA50979B1 - Application de totarol et composition pharmaceutique contenant du totarol - Google Patents
Application de totarol et composition pharmaceutique contenant du totarolInfo
- Publication number
- MA50979B1 MA50979B1 MA50979A MA50979A MA50979B1 MA 50979 B1 MA50979 B1 MA 50979B1 MA 50979 A MA50979 A MA 50979A MA 50979 A MA50979 A MA 50979A MA 50979 B1 MA50979 B1 MA 50979B1
- Authority
- MA
- Morocco
- Prior art keywords
- totarol
- treatment
- weight
- parts
- pharmaceutical composition
- Prior art date
Links
- CKZZREIPBTYJEQ-UHFFFAOYSA-N Totarol Natural products C1CC2C(C)(C)CCCC2(C)C2=C1C(C(C)C)=C(C)C=C2 CKZZREIPBTYJEQ-UHFFFAOYSA-N 0.000 title abstract 4
- ZRVDANDJSTYELM-FXAWDEMLSA-N totarol Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C)C1=C2C(C(C)C)=C(O)C=C1 ZRVDANDJSTYELM-FXAWDEMLSA-N 0.000 title abstract 4
- 229940074347 totarol Drugs 0.000 title abstract 4
- ZRVDANDJSTYELM-UHFFFAOYSA-N trans-totarol Natural products C1CC2C(C)(C)CCCC2(C)C2=C1C(C(C)C)=C(O)C=C2 ZRVDANDJSTYELM-UHFFFAOYSA-N 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 4
- 230000004054 inflammatory process Effects 0.000 abstract 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 4
- 238000011282 treatment Methods 0.000 abstract 4
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 235000014655 lactic acid Nutrition 0.000 abstract 2
- 239000004310 lactic acid Substances 0.000 abstract 2
- 210000004400 mucous membrane Anatomy 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 208000024891 symptom Diseases 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention concerne l'application de totarol pour la production d'une préparation pour le traitement d'inflammations de la membrane muqueuse vaginale d'origine bactérienne, pour le soulagement de symptômes dans un tel traitement et pour la prophylaxie et la prévention de récidives de telles inflammations. L'invention concerne également une composition pharmaceutique pour le traitement d'inflammations de la membrane muqueuse vaginale d'origine bactérienne, pour le soulagement de symptômes dans un tel traitement et pour la prophylaxie et la prévention de récidives de telles inflammations, la composition contenant de 75 à 95 parties en poids d'un dérivé de cellulose, de 0,5 à 5 parties en poids d'acide lactique, de 0,5 à 5 parties en poids d'un polymère basique, le rapport stœchiométrique entre l'acide lactique et le polymère basique étant compris dans la plage de 1:1 à 8:1 et comprenant du totarol en une quantité de 0,001 à 5 parties en poids en tant que principe actif.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL422140A PL236429B1 (pl) | 2017-07-06 | 2017-07-06 | Zastosowanie totarolu do wytwarzania preparatu do leczenia bakteryjnego zakażenia pochwy i kompozycja farmaceutyczna do zastosowania w leczeniu stanów zapalnych pochwy o podłożu bakteryjnym |
PCT/PL2018/000066 WO2019009739A1 (fr) | 2017-07-06 | 2018-07-04 | Application de totarol et composition pharmaceutique contenant du totarol |
Publications (2)
Publication Number | Publication Date |
---|---|
MA50979A MA50979A (fr) | 2020-10-14 |
MA50979B1 true MA50979B1 (fr) | 2022-11-30 |
Family
ID=63518002
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050980A MA50980A (fr) | 2017-07-06 | 2018-07-04 | Application de totarol et composition pharmaceutique contenant du totarol |
MA50979A MA50979B1 (fr) | 2017-07-06 | 2018-07-04 | Application de totarol et composition pharmaceutique contenant du totarol |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050980A MA50980A (fr) | 2017-07-06 | 2018-07-04 | Application de totarol et composition pharmaceutique contenant du totarol |
Country Status (19)
Country | Link |
---|---|
US (1) | US11534412B2 (fr) |
EP (1) | EP3648751B1 (fr) |
KR (1) | KR20200024921A (fr) |
BR (1) | BR112019027839A2 (fr) |
CA (1) | CA3066602C (fr) |
CL (1) | CL2019003720A1 (fr) |
DK (1) | DK3648751T3 (fr) |
ES (1) | ES2929646T3 (fr) |
HR (1) | HRP20221338T1 (fr) |
HU (1) | HUE060300T2 (fr) |
IL (1) | IL271875B2 (fr) |
LT (1) | LT3648751T (fr) |
MA (2) | MA50980A (fr) |
PL (1) | PL236429B1 (fr) |
PT (1) | PT3648751T (fr) |
RS (1) | RS63728B1 (fr) |
SI (1) | SI3648751T1 (fr) |
UA (1) | UA126031C2 (fr) |
WO (1) | WO2019009739A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114948891A (zh) * | 2021-06-07 | 2022-08-30 | 南通联亚药业股份有限公司 | 药物组合物 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL201869A1 (pl) | 1977-10-29 | 1979-05-21 | Inst Przemyslu Organiczego | Sposob wytwarzania masy kablowej odpornej na dzialanie termitow |
PL107491B1 (pl) | 1977-10-29 | 1980-02-29 | Przemyslowy Instytut Automatyk | Czujnik dwustrunowy do pomiaru malych przesuniec |
JP2700071B2 (ja) | 1988-06-10 | 1998-01-19 | 株式会社資生堂 | 抗菌剤及びそれを用いた皮膚外用剤、口腔用組成物 |
PL166898B1 (pl) | 1992-02-13 | 1995-06-30 | Akad Medyczna | Sposób wytwarzania kompleksu metylocelulozy z kwasem mlekowym |
US6534548B1 (en) * | 2001-10-02 | 2003-03-18 | Kimberly-Clark Worldwide, Inc. | Isoprenoid compositions for the inhibition of exoprotein production from gram positive bacteria |
PL194437B1 (pl) | 2002-06-05 | 2007-05-31 | Akademia Medyczna Im Piastow S | Sposób wytwarzania kompleksu na bazie kwasu mlekowego |
NZ530834A (en) | 2004-01-28 | 2007-06-29 | Owen John Catchpole | Near-critical extraction of totarol and/or a product containing totarol |
US20090312279A1 (en) * | 2005-12-23 | 2009-12-17 | Sterilex Technologies, Llc | Antimicrobial compositions |
EP1925302A1 (fr) * | 2006-11-24 | 2008-05-28 | DSMIP Assets B.V. | Composition diététique où pharmaceutique contentant de diterpène tricycliques et leurs dérivés pour le traitment de la dépression |
EP1925301A1 (fr) * | 2006-11-24 | 2008-05-28 | DSMIP Assets B.V. | Utilisation de diterpènes tricycliques et de leurs dérivés pour le traitement et la prévention d'affections inflammatoires et/ou des articulations |
JP5471335B2 (ja) * | 2009-11-17 | 2014-04-16 | ライオン株式会社 | 口腔バイオフィルム殺菌剤 |
BR112014014036B1 (pt) * | 2011-12-15 | 2018-02-14 | Colgate-Palmolive Company | Composição antibacteriana de timol e totarol |
WO2014137231A2 (fr) | 2013-03-07 | 2014-09-12 | T2G Biotechnology Limited | Formulations d'extrait de totarol et leurs utilisations |
DE102013108870A1 (de) * | 2013-08-16 | 2015-02-19 | Aimecs Gmbh | Mittel zur Reinigung und zum Schutz von technischen Oberflächen |
CN104027260A (zh) | 2014-06-20 | 2014-09-10 | 广州薇美姿个人护理用品有限公司 | 一种含有桃柘酚的口腔护理用品 |
CN104688810A (zh) | 2014-12-29 | 2015-06-10 | 昆明皕凯科技有限公司 | 一种基于天然植物原料的抗菌组合物及其应用 |
CN106581687A (zh) * | 2016-12-22 | 2017-04-26 | 吉林大学 | 以乳清蛋白为基质的桃柁酚抗菌纳米水凝胶及其制备方法 |
-
2017
- 2017-07-06 PL PL422140A patent/PL236429B1/pl unknown
-
2018
- 2018-07-04 MA MA050980A patent/MA50980A/fr unknown
- 2018-07-04 KR KR1020207003488A patent/KR20200024921A/ko not_active Application Discontinuation
- 2018-07-04 CA CA3066602A patent/CA3066602C/fr active Active
- 2018-07-04 HR HRP20221338TT patent/HRP20221338T1/hr unknown
- 2018-07-04 BR BR112019027839-7A patent/BR112019027839A2/pt unknown
- 2018-07-04 EP EP18765765.5A patent/EP3648751B1/fr active Active
- 2018-07-04 DK DK18765765.5T patent/DK3648751T3/da active
- 2018-07-04 WO PCT/PL2018/000066 patent/WO2019009739A1/fr unknown
- 2018-07-04 MA MA50979A patent/MA50979B1/fr unknown
- 2018-07-04 SI SI201830794T patent/SI3648751T1/sl unknown
- 2018-07-04 UA UAA201911771A patent/UA126031C2/uk unknown
- 2018-07-04 RS RS20221013A patent/RS63728B1/sr unknown
- 2018-07-04 ES ES18765765T patent/ES2929646T3/es active Active
- 2018-07-04 LT LTEPPCT/PL2018/000066T patent/LT3648751T/lt unknown
- 2018-07-04 US US16/629,005 patent/US11534412B2/en active Active
- 2018-07-04 HU HUE18765765A patent/HUE060300T2/hu unknown
- 2018-07-04 PT PT187657655T patent/PT3648751T/pt unknown
-
2019
- 2019-12-18 CL CL2019003720A patent/CL2019003720A1/es unknown
-
2020
- 2020-01-06 IL IL271875A patent/IL271875B2/en unknown
Also Published As
Publication number | Publication date |
---|---|
RS63728B1 (sr) | 2022-12-30 |
WO2019009739A4 (fr) | 2019-02-28 |
DK3648751T3 (da) | 2022-11-21 |
MA50980A (fr) | 2020-10-14 |
PL422140A1 (pl) | 2019-01-14 |
CA3066602C (fr) | 2024-01-02 |
US20200289429A1 (en) | 2020-09-17 |
RU2020104832A (ru) | 2021-08-06 |
SI3648751T1 (sl) | 2023-03-31 |
ES2929646T3 (es) | 2022-12-01 |
BR112019027839A2 (pt) | 2020-07-07 |
IL271875B2 (en) | 2023-02-01 |
US11534412B2 (en) | 2022-12-27 |
HRP20221338T1 (hr) | 2022-12-23 |
PL236429B1 (pl) | 2021-01-11 |
KR20200024921A (ko) | 2020-03-09 |
CL2019003720A1 (es) | 2020-05-22 |
IL271875A (en) | 2020-02-27 |
PT3648751T (pt) | 2022-10-20 |
WO2019009739A1 (fr) | 2019-01-10 |
MA50979A (fr) | 2020-10-14 |
LT3648751T (lt) | 2022-12-12 |
RU2020104832A3 (fr) | 2021-10-08 |
CA3066602A1 (fr) | 2019-01-10 |
HUE060300T2 (hu) | 2023-02-28 |
UA126031C2 (uk) | 2022-08-03 |
EP3648751A1 (fr) | 2020-05-13 |
EP3648751B1 (fr) | 2022-09-28 |
IL271875B (en) | 2022-10-01 |
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