MA49521A - Nanoparticule, agent de contraste pour imagerie par résonance magnétique la contenant, et composé ligand - Google Patents

Nanoparticule, agent de contraste pour imagerie par résonance magnétique la contenant, et composé ligand

Info

Publication number
MA49521A
MA49521A MA049521A MA49521A MA49521A MA 49521 A MA49521 A MA 49521A MA 049521 A MA049521 A MA 049521A MA 49521 A MA49521 A MA 49521A MA 49521 A MA49521 A MA 49521A
Authority
MA
Morocco
Prior art keywords
nanoparticle
contrast
agent
magnetic resonance
resonance imaging
Prior art date
Application number
MA049521A
Other languages
English (en)
Inventor
Takuzo Aida
Ichio Aoki
Daigo Miyajima
Seunghyun Sim
Toshiaki Takeuchi
Original Assignee
National Institutes For Quantum And Radiological Science And Tech
Riken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Institutes For Quantum And Radiological Science And Tech, Riken filed Critical National Institutes For Quantum And Radiological Science And Tech
Publication of MA49521A publication Critical patent/MA49521A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A61K49/1833—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Composite Materials (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA049521A 2017-06-28 2018-06-27 Nanoparticule, agent de contraste pour imagerie par résonance magnétique la contenant, et composé ligand MA49521A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2017126755 2017-06-28

Publications (1)

Publication Number Publication Date
MA49521A true MA49521A (fr) 2020-05-06

Family

ID=64742350

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049521A MA49521A (fr) 2017-06-28 2018-06-27 Nanoparticule, agent de contraste pour imagerie par résonance magnétique la contenant, et composé ligand

Country Status (19)

Country Link
US (1) US11389550B2 (fr)
EP (1) EP3646888A4 (fr)
JP (1) JP7107532B2 (fr)
KR (1) KR20200018579A (fr)
CN (1) CN110799219B (fr)
AU (1) AU2018292927B2 (fr)
BR (1) BR112019027478A2 (fr)
CA (1) CA3068215A1 (fr)
CO (1) CO2020000940A2 (fr)
IL (1) IL271622A (fr)
JO (1) JOP20190290A1 (fr)
MA (1) MA49521A (fr)
MY (1) MY201491A (fr)
PH (1) PH12019502882A1 (fr)
RU (1) RU2767430C2 (fr)
SG (1) SG11201912664WA (fr)
UA (1) UA125049C2 (fr)
WO (1) WO2019004297A1 (fr)
ZA (1) ZA202000265B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021007731A (es) * 2018-12-27 2021-08-05 Astellas Pharma Inc Nanoparticula, agente de contraste para formacion de imagenes por resonancia magnetica que comprende la misma y un compuesto de ligando zwitterionico.
MX2021007832A (es) * 2018-12-27 2021-08-11 Astellas Pharma Inc Metodo para producir nanoparticulas que tienen particulas metalicas que contienen oxido de hierro a las cuales se unen por coordinacion uno o mas ligandos hidrofilos.

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123542A (en) 1960-10-13 1964-03-03 Electrolytic marking medium
US20100166664A1 (en) 2008-12-29 2010-07-01 General Electric Company Nanoparticle contrast agents for diagnostic imaging
US8574549B2 (en) 2008-12-29 2013-11-05 General Electric Company Nanoparticle contrast agents for diagnostic imaging
US8728440B2 (en) 2012-08-23 2014-05-20 General Electric Company Nanoparticulate compositions for diagnostic imaging
US9399075B2 (en) 2008-12-29 2016-07-26 General Electric Company Nanoparticle contrast agents for diagnostic imaging
CN102333547A (zh) 2008-12-29 2012-01-25 通用电气公司 用于诊断成像的纳米颗粒造影剂
US8728529B2 (en) 2008-12-29 2014-05-20 General Electric Company Nanoparticle contrast agents for diagnostic imaging
US9205155B2 (en) 2009-10-30 2015-12-08 General Electric Company Treating water insoluble nanoparticles with hydrophilic alpha-hydroxyphosphonic acid conjugates, the so modified nanoparticles and their use as contrast agents
KR20130045647A (ko) * 2011-10-26 2013-05-06 한국기초과학지원연구원 양쪽성 이온으로 코팅된 자기공명영상 조영제
WO2013090601A2 (fr) 2011-12-16 2013-06-20 Massachusetts Institute Of Technology Nanoparticules compactes pour des applications biologiques
US8821838B2 (en) 2012-08-23 2014-09-02 General Electric Company Nanoparticulate compositions for diagnostic imaging
CN104740654B (zh) 2013-12-30 2017-12-29 中国科学院化学研究所 磁性纳米颗粒磁共振造影剂和增强磁性纳米颗粒弛豫率的方法
JP6590809B2 (ja) 2014-01-07 2019-10-16 コロロッビア イタリア ソシエタ ペル アチオニ カテコールで官能化された磁性ナノ粒子、その生成および使用
JP6471227B2 (ja) 2014-09-15 2019-02-13 マサチューセッツ インスティテュート オブ テクノロジー 磁気共鳴画像法用途のためのナノ粒子
JP6577250B2 (ja) 2015-06-02 2019-09-18 国立大学法人 東京大学 複合半透膜
CN106390146A (zh) 2015-08-03 2017-02-15 天津大学 聚磺酸甜菜碱两性电解质修饰的磁性纳米粒子及其制备方法和应用

Also Published As

Publication number Publication date
CN110799219B (zh) 2023-01-06
CO2020000940A2 (es) 2020-02-18
AU2018292927A1 (en) 2020-02-06
UA125049C2 (uk) 2021-12-29
BR112019027478A2 (pt) 2020-07-07
EP3646888A1 (fr) 2020-05-06
CA3068215A1 (fr) 2019-01-03
WO2019004297A1 (fr) 2019-01-03
JOP20190290A1 (ar) 2019-12-19
MY201491A (en) 2024-02-27
US20200330617A1 (en) 2020-10-22
RU2767430C2 (ru) 2022-03-17
RU2019143780A3 (fr) 2021-08-27
KR20200018579A (ko) 2020-02-19
JPWO2019004297A1 (ja) 2020-04-30
ZA202000265B (en) 2021-07-28
JP7107532B2 (ja) 2022-07-27
PH12019502882A1 (en) 2020-10-26
SG11201912664WA (en) 2020-01-30
RU2019143780A (ru) 2021-06-25
IL271622A (en) 2020-02-27
EP3646888A4 (fr) 2021-04-14
US11389550B2 (en) 2022-07-19
CN110799219A (zh) 2020-02-14
AU2018292927B2 (en) 2021-11-25

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