MA45691A - Formes solides d'inhibiteur de ttk - Google Patents

Formes solides d'inhibiteur de ttk

Info

Publication number
MA45691A
MA45691A MA045691A MA45691A MA45691A MA 45691 A MA45691 A MA 45691A MA 045691 A MA045691 A MA 045691A MA 45691 A MA45691 A MA 45691A MA 45691 A MA45691 A MA 45691A
Authority
MA
Morocco
Prior art keywords
solid forms
ttk inhibitor
ttk
inhibitor
solid
Prior art date
Application number
MA045691A
Other languages
English (en)
Inventor
Sze-Wan Li
Heinz W Pauls
Peter Brent Sampson
Original Assignee
Univ Health Network
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Health Network filed Critical Univ Health Network
Publication of MA45691A publication Critical patent/MA45691A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54—Organic compounds
    • C30B29/58—Macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
    • C30B7/02—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions by evaporation of the solvent
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
    • C30B7/14—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions the crystallising materials being formed by chemical reactions in the solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
MA045691A 2016-07-18 2017-07-13 Formes solides d'inhibiteur de ttk MA45691A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662363424P 2016-07-18 2016-07-18

Publications (1)

Publication Number Publication Date
MA45691A true MA45691A (fr) 2019-05-22

Family

ID=60991755

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045691A MA45691A (fr) 2016-07-18 2017-07-13 Formes solides d'inhibiteur de ttk

Country Status (26)

Country Link
US (3) US10584130B2 (fr)
EP (1) EP3484888B1 (fr)
JP (2) JP6961675B2 (fr)
KR (2) KR20230074839A (fr)
CN (2) CN115093416B (fr)
AU (2) AU2017299850B2 (fr)
BR (1) BR112019000813A2 (fr)
CA (1) CA3030230A1 (fr)
DK (1) DK3484888T3 (fr)
ES (1) ES2945108T3 (fr)
FI (1) FI3484888T5 (fr)
HR (1) HRP20230481T1 (fr)
HU (1) HUE061872T2 (fr)
IL (1) IL264173A (fr)
LT (1) LT3484888T (fr)
MA (1) MA45691A (fr)
MX (2) MX2019000744A (fr)
NZ (1) NZ749844A (fr)
PL (1) PL3484888T3 (fr)
PT (1) PT3484888T (fr)
RS (1) RS64210B1 (fr)
RU (2) RU2753905C2 (fr)
SG (2) SG10202103332UA (fr)
SI (1) SI3484888T1 (fr)
TW (2) TWI745400B (fr)
WO (1) WO2018014116A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115093416B (zh) 2016-07-18 2024-04-12 大学健康网络 Ttk抑制剂的固体形式

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732717A (zh) 2001-02-21 2010-06-16 诺华疫苗和诊断公司 用于诊断和作为癌症治疗靶标的ttk
KR20070090172A (ko) * 2004-11-04 2007-09-05 버텍스 파마슈티칼스 인코포레이티드 단백질 키나아제의 억제제로서 유용한피라졸로[1,5-ａ]피리미딘
TW201107329A (en) * 2009-07-30 2011-03-01 Oncotherapy Science Inc Fused imidazole derivative having ttk inhibitory action
TWI541243B (zh) * 2010-09-10 2016-07-11 拜耳知識產權公司 經取代咪唑并嗒
CA2821829A1 (fr) * 2010-12-17 2012-06-21 Bayer Intellectual Property Gmbh Imidazopyrazines pour l'utilisation en tant qu'inhibiteurs de mps-1 et de tkk dans le traitement de troubles d'hyperproliferation
WO2014075168A1 (fr) 2012-11-16 2014-05-22 University Health Network Composés de pyrazolopyrimidine
EA029372B1 (ru) * 2013-11-15 2018-03-30 Юниверсити Хелс Нетуорк Пиразолопиримидиновые соединения
CN115093416B (zh) 2016-07-18 2024-04-12 大学健康网络 Ttk抑制剂的固体形式

Also Published As

Publication number Publication date
US20200270259A1 (en) 2020-08-27
TW201803876A (zh) 2018-02-01
US20190292193A1 (en) 2019-09-26
JP7263473B2 (ja) 2023-04-24
KR20190029601A (ko) 2019-03-20
SG11201900113UA (en) 2019-02-27
US20220089601A1 (en) 2022-03-24
EP3484888A1 (fr) 2019-05-22
NZ749844A (en) 2024-03-22
KR20230074839A (ko) 2023-05-31
SG10202103332UA (en) 2021-05-28
TWI824313B (zh) 2023-12-01
US11878980B2 (en) 2024-01-23
CN115093416B (zh) 2024-04-12
CN109476667A (zh) 2019-03-15
DK3484888T3 (da) 2023-05-30
MX2019000744A (es) 2019-05-02
PT3484888T (pt) 2023-05-26
CA3030230A1 (fr) 2018-01-25
PL3484888T3 (pl) 2023-06-26
JP6961675B2 (ja) 2021-11-05
WO2018014116A1 (fr) 2018-01-25
LT3484888T (lt) 2023-06-12
BR112019000813A2 (pt) 2019-04-30
RU2019101109A3 (fr) 2021-02-05
TWI745400B (zh) 2021-11-11
FI3484888T5 (fi) 2024-02-26
HUE061872T2 (hu) 2023-08-28
MX2021008658A (es) 2021-08-19
JP2019521155A (ja) 2019-07-25
IL264173A (en) 2019-02-28
RU2021124795A (ru) 2021-09-14
CN109476667B (zh) 2022-06-28
AU2021221447A1 (en) 2021-10-07
RU2019101109A (ru) 2020-08-18
EP3484888A4 (fr) 2020-01-08
ES2945108T3 (es) 2023-06-28
AU2021221447B2 (en) 2023-09-21
SI3484888T1 (sl) 2023-07-31
AU2017299850A1 (en) 2019-01-24
RU2753905C2 (ru) 2021-08-24
RS64210B1 (sr) 2023-06-30
TW202202507A (zh) 2022-01-16
JP2022001598A (ja) 2022-01-06
US11104681B2 (en) 2021-08-31
CN115093416A (zh) 2022-09-23
AU2017299850A8 (en) 2019-03-21
FI3484888T3 (fi) 2023-05-03
US10584130B2 (en) 2020-03-10
KR102537088B1 (ko) 2023-05-25
HRP20230481T1 (hr) 2023-07-21
EP3484888B1 (fr) 2023-02-22
AU2017299850B2 (en) 2021-05-27

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