MA39715A - Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation - Google Patents
Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisationInfo
- Publication number
- MA39715A MA39715A MA039715A MA39715A MA39715A MA 39715 A MA39715 A MA 39715A MA 039715 A MA039715 A MA 039715A MA 39715 A MA39715 A MA 39715A MA 39715 A MA39715 A MA 39715A
- Authority
- MA
- Morocco
- Prior art keywords
- pyrrolo
- quinoline
- dihydro
- preparation
- disodium salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
La présente invention concerne une forme polymorphe de pqq et/ou de ses sels, représentée par la formule (i), dans laquelle "n" et "m" sont choisis dans le groupe constitué par : (a) "n" = 3, "m" = 0 et (b) "n" = 1, "m" = 2; et r3 est na+. Un procédé de préparation de la forme polymorphe du composé de formule (i) et/ou de ses sels, une composition les contenant et leur utilisation sont en outre décrits.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1988CH2014 | 2014-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA39715A true MA39715A (fr) | 2015-10-22 |
Family
ID=53059367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA039715A MA39715A (fr) | 2014-04-16 | 2015-04-14 | Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation |
Country Status (6)
Country | Link |
---|---|
US (1) | US20170022200A1 (fr) |
EP (1) | EP3131899A1 (fr) |
JP (1) | JP2017513863A (fr) |
CN (1) | CN106255691A (fr) |
MA (1) | MA39715A (fr) |
WO (1) | WO2015159236A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10364244B2 (en) * | 2015-09-25 | 2019-07-30 | Zhejiang Hisun Pharmaceutical Co., Ltd. | Crystal form of pyrroloquinoline quinone sodium salt and preparation method and use thereof |
CN105315278B (zh) * | 2015-11-02 | 2018-01-16 | 诸城市浩天药业有限公司 | 吡咯喹啉醌a晶型及其制备方法 |
CN105218543B (zh) * | 2015-11-02 | 2017-05-10 | 诸城市浩天药业有限公司 | 吡咯喹啉醌b晶型及其制备方法 |
KR20210052433A (ko) * | 2018-08-30 | 2021-05-10 | 미쯔비시 가스 케미칼 컴파니, 인코포레이티드 | 광열화억제제, 그것을 포함하는 음료, 및 광열화억제방법 |
JP7301347B2 (ja) * | 2019-05-22 | 2023-07-03 | 株式会社ブルーム・クラシック | サーチュイン1活性化剤及びサーチュイン1活性化用皮膚化粧料 |
CN112125899B (zh) * | 2019-06-24 | 2023-01-03 | 浙江可明生物医药有限公司 | 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3475969B2 (ja) | 1993-08-27 | 2003-12-10 | 大日本インキ化学工業株式会社 | 共重合体樹脂エマルジョン、その製造方法及び防湿加工用組成物 |
US20070072894A1 (en) | 2005-03-24 | 2007-03-29 | Kempf J V | Synthesis of pyrroloquinoline quinone (PQQ) |
CN101193888A (zh) * | 2005-03-24 | 2008-06-04 | Clf医疗技术加速程序有限公司 | 吡咯喹啉醌(pqq)的合成方法 |
CN101885725A (zh) * | 2009-05-12 | 2010-11-17 | 江苏道琪生物科技有限公司 | 吡咯喹啉醌钠盐衍生物及其制备方法 |
US9163014B2 (en) | 2009-07-16 | 2015-10-20 | Mitsubishi Gas Chemical Company, Inc. | Crystals of pyrroloquinolinequinone sodium salts |
JPWO2011055796A1 (ja) * | 2009-11-06 | 2013-03-28 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンのフリー体 |
JP5979376B2 (ja) * | 2010-11-26 | 2016-08-24 | 三菱瓦斯化学株式会社 | 溶解性の高いピロロキノリンキノン塩及びその製造方法 |
DK2722331T3 (da) * | 2011-06-16 | 2017-11-20 | Mitsubishi Gas Chemical Co | Pyrroloquinolinquinondinatriumsaltkrystal og fremgangsmåde til fremstilling af samme |
JP2013112677A (ja) * | 2011-12-01 | 2013-06-10 | Mitsubishi Gas Chemical Co Inc | ピロロキノリンキノンジナトリウム結晶 |
JP5962254B2 (ja) * | 2012-06-27 | 2016-08-03 | 三菱瓦斯化学株式会社 | 高品質ピロロキノリンキノンの製造方法 |
-
2015
- 2015-04-14 MA MA039715A patent/MA39715A/fr unknown
- 2015-04-15 US US15/302,720 patent/US20170022200A1/en not_active Abandoned
- 2015-04-15 CN CN201580019780.7A patent/CN106255691A/zh active Pending
- 2015-04-15 EP EP15721334.9A patent/EP3131899A1/fr not_active Withdrawn
- 2015-04-15 JP JP2016563108A patent/JP2017513863A/ja active Pending
- 2015-04-15 WO PCT/IB2015/052748 patent/WO2015159236A1/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
US20170022200A1 (en) | 2017-01-26 |
WO2015159236A1 (fr) | 2015-10-22 |
JP2017513863A (ja) | 2017-06-01 |
CN106255691A (zh) | 2016-12-21 |
EP3131899A1 (fr) | 2017-02-22 |
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