MA38849A1 - Nouveaux composés d'indazole pour le traitement du diabete et leur procede de preparation - Google Patents
Nouveaux composés d'indazole pour le traitement du diabete et leur procede de preparationInfo
- Publication number
- MA38849A1 MA38849A1 MA38849A MA38849A MA38849A1 MA 38849 A1 MA38849 A1 MA 38849A1 MA 38849 A MA38849 A MA 38849A MA 38849 A MA38849 A MA 38849A MA 38849 A1 MA38849 A1 MA 38849A1
- Authority
- MA
- Morocco
- Prior art keywords
- diabetes
- preparation
- treatment
- indazole compounds
- novel indazole
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Le brevet divulgue de nouveaux composés d'indazole de formule générale 1 et des analogues de ceux-ci, leur utilisation pour le traitement du diabète, des complications diabétiques, du dysfonctionnement cardiovasculaire ou de maladies associées, des compositions pharmaceutiques les contenant et leurs procédés de préparation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2296DE2013 | 2013-07-31 | ||
PCT/IN2014/000507 WO2015015519A1 (fr) | 2013-07-31 | 2014-07-31 | Nouveaux composés d'indazole et leur procede de preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
MA38849A1 true MA38849A1 (fr) | 2017-12-29 |
MA38849B1 MA38849B1 (fr) | 2018-09-28 |
Family
ID=51795688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA38849A MA38849B1 (fr) | 2013-07-31 | 2014-07-31 | Nouveaux composés d'indazole pour le traitement du diabete et leur procede de preparation |
Country Status (18)
Country | Link |
---|---|
US (1) | US9737510B2 (fr) |
EP (1) | EP3027605B1 (fr) |
JP (1) | JP6474808B2 (fr) |
KR (1) | KR20160053916A (fr) |
CN (1) | CN106103427B (fr) |
AU (1) | AU2014297912A1 (fr) |
BR (1) | BR112016002176A2 (fr) |
CA (1) | CA2919953A1 (fr) |
DK (1) | DK3027605T3 (fr) |
EA (1) | EA201690240A1 (fr) |
ES (1) | ES2656475T3 (fr) |
MA (1) | MA38849B1 (fr) |
MD (1) | MD20160019A2 (fr) |
MX (1) | MX2016001331A (fr) |
MY (1) | MY176807A (fr) |
SG (1) | SG11201600744UA (fr) |
WO (1) | WO2015015519A1 (fr) |
ZA (1) | ZA201601177B (fr) |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0047328B1 (fr) | 1980-09-05 | 1984-05-09 | Siegfried Aktiengesellschaft | Dérivés de 1H- et 2H-indazole et médicament les contenant |
PH27357A (en) | 1989-09-22 | 1993-06-21 | Fujisawa Pharmaceutical Co | Pyrazole derivatives and pharmaceutical compositions comprising the same |
WO1999009986A1 (fr) * | 1997-08-22 | 1999-03-04 | Kyowa Hakko Kogyo Co., Ltd. | Derives de 4-aminoquinazoline |
ZA9811672B (en) * | 1997-12-19 | 2000-06-19 | Lilly Co Eli | Hypoglycemic imidazoline compounds. |
JP2000154139A (ja) * | 1998-09-16 | 2000-06-06 | Kyowa Hakko Kogyo Co Ltd | 縮環ピラジン誘導体 |
YU54202A (sh) | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
US6982274B2 (en) | 2001-04-16 | 2006-01-03 | Eisai Co., Ltd. | 1H-indazole compound |
EP1427707A1 (fr) * | 2001-09-19 | 2004-06-16 | Pharmacia Corporation | Composes d'indazole substitues destines au traitement de l'inflammation |
US20040009976A1 (en) * | 2002-04-30 | 2004-01-15 | Kumiko Takeuchi | Hypoglycemic imidazoline compounds |
US6878735B2 (en) | 2002-05-31 | 2005-04-12 | Board Of Trustees Of Michigan State University | Multi-substituted imidazolines and method of use thereof |
US20050090529A1 (en) * | 2003-07-31 | 2005-04-28 | Pfizer Inc | 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
EA200800013A1 (ru) * | 2005-06-10 | 2008-06-30 | Эликсир Фармасьютикалз, Инк. | Сульфонамидные соединения и их применение |
JP2013501792A (ja) | 2009-08-10 | 2013-01-17 | サミュメッド リミテッド ライアビリティ カンパニー | Wnt/b−カテニンシグナル伝達経路阻害剤としてのインダゾールおよびその治療的使用 |
US7947728B1 (en) | 2009-11-11 | 2011-05-24 | Hoffmann-La Roche Inc. | Indole and indazole analogs as glycogen synthase activators |
-
2014
- 2014-07-31 EP EP14789631.0A patent/EP3027605B1/fr active Active
- 2014-07-31 AU AU2014297912A patent/AU2014297912A1/en not_active Abandoned
- 2014-07-31 JP JP2016530671A patent/JP6474808B2/ja not_active Expired - Fee Related
- 2014-07-31 MX MX2016001331A patent/MX2016001331A/es unknown
- 2014-07-31 US US14/908,805 patent/US9737510B2/en active Active
- 2014-07-31 CN CN201480048261.9A patent/CN106103427B/zh not_active Expired - Fee Related
- 2014-07-31 WO PCT/IN2014/000507 patent/WO2015015519A1/fr active Application Filing
- 2014-07-31 CA CA2919953A patent/CA2919953A1/fr not_active Abandoned
- 2014-07-31 SG SG11201600744UA patent/SG11201600744UA/en unknown
- 2014-07-31 BR BR112016002176A patent/BR112016002176A2/pt not_active Application Discontinuation
- 2014-07-31 DK DK14789631.0T patent/DK3027605T3/en active
- 2014-07-31 KR KR1020167005168A patent/KR20160053916A/ko not_active Application Discontinuation
- 2014-07-31 MY MYPI2016700340A patent/MY176807A/en unknown
- 2014-07-31 ES ES14789631.0T patent/ES2656475T3/es active Active
- 2014-07-31 MD MDA20160019A patent/MD20160019A2/ro not_active Application Discontinuation
- 2014-07-31 EA EA201690240A patent/EA201690240A1/ru unknown
- 2014-07-31 MA MA38849A patent/MA38849B1/fr unknown
-
2016
- 2016-02-22 ZA ZA2016/01177A patent/ZA201601177B/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA38849B1 (fr) | 2018-09-28 |
JP6474808B2 (ja) | 2019-02-27 |
EP3027605B1 (fr) | 2017-11-08 |
DK3027605T3 (en) | 2018-01-22 |
MD20160019A2 (ro) | 2016-06-30 |
MX2016001331A (es) | 2017-02-06 |
AU2014297912A1 (en) | 2016-02-25 |
ES2656475T3 (es) | 2018-02-27 |
ZA201601177B (en) | 2017-11-29 |
BR112016002176A2 (pt) | 2017-08-01 |
CN106103427B (zh) | 2019-07-16 |
CA2919953A1 (fr) | 2015-02-05 |
WO2015015519A1 (fr) | 2015-02-05 |
EA201690240A1 (ru) | 2016-10-31 |
EP3027605A1 (fr) | 2016-06-08 |
SG11201600744UA (en) | 2016-02-26 |
MY176807A (en) | 2020-08-21 |
CN106103427A (zh) | 2016-11-09 |
KR20160053916A (ko) | 2016-05-13 |
JP2016525570A (ja) | 2016-08-25 |
US9737510B2 (en) | 2017-08-22 |
US20160185759A1 (en) | 2016-06-30 |
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