MA33747B1 - Anticorps monoclonaux diriges contre la progastrine et leurs utilisations - Google Patents
Anticorps monoclonaux diriges contre la progastrine et leurs utilisationsInfo
- Publication number
- MA33747B1 MA33747B1 MA34864A MA34864A MA33747B1 MA 33747 B1 MA33747 B1 MA 33747B1 MA 34864 A MA34864 A MA 34864A MA 34864 A MA34864 A MA 34864A MA 33747 B1 MA33747 B1 MA 33747B1
- Authority
- MA
- Morocco
- Prior art keywords
- monoclonal antibodies
- antibodies against
- methods
- progastrin
- gastrin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/595—Gastrins; Cholecystokinins [CCK]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne des anticorps monoclonaux contre la progastrine, des fragments de ceux-ci, des compositions comprenant les anticorps monoclonaux contre la progastrine, et des procédés de fabrication et d'utilisation d'anticorps monoclonaux contre la progastrine ainsi que des compositions les contenant. La présente invention concerne des procédés de traitement du cancer colorectal avec des anticorps monoclonaux contre la progastrine et des compositions comprenant des anticorps monoclonaux contre la progastrine ou des fragments de ceux-ci. La présente invention concerne en outre des procédés comprenant la détection de la progastrine, y compris des procédés de diagnostic du cancer colorectal et des procédés de surveillance de l'efficacité d'une thérapie anticancéreuse chez des sujets souffrant du cancer colorectal.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25262509P | 2009-10-16 | 2009-10-16 | |
PCT/EP2010/006329 WO2011045080A2 (fr) | 2009-10-16 | 2010-10-15 | Anticorps monoclonaux contre la progastrine et leurs utilisations |
Publications (1)
Publication Number | Publication Date |
---|---|
MA33747B1 true MA33747B1 (fr) | 2012-11-01 |
Family
ID=43086711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA34864A MA33747B1 (fr) | 2009-10-16 | 2012-05-11 | Anticorps monoclonaux diriges contre la progastrine et leurs utilisations |
Country Status (41)
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7854932B2 (en) | 2006-12-19 | 2010-12-21 | The Board Of Regents Of The University Of Texas System | Immunogenic compositions comprising progastrin and uses thereof |
US8136651B2 (en) * | 2007-12-14 | 2012-03-20 | The Procter & Gamble Company | Method and apparatus for orienting articles |
AR078659A1 (es) * | 2009-10-16 | 2011-11-23 | Biorealites S A | Anticuerpos monoclonales contra progastrina humana y sus usos |
US8900588B2 (en) * | 2010-01-08 | 2014-12-02 | Les Laboratories Servier | Methods for treating breast cancer |
US8900817B2 (en) * | 2010-01-08 | 2014-12-02 | Les Laboratories Servier | Progastrin and liver pathologies |
JP5829672B2 (ja) * | 2010-03-24 | 2015-12-09 | レ ラボラトワール セルヴィエ | 結腸直腸及び胃腸癌の予防 |
EA028515B1 (ru) * | 2010-07-26 | 2017-11-30 | Ле Лаборатуар Сервье | Способы и композиции для терапии рака печени |
US8785603B2 (en) | 2011-05-20 | 2014-07-22 | Siemens Healthcare Diagnostics Inc. | Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof |
EP2715364A1 (fr) | 2011-06-01 | 2014-04-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédé pour prédire le risque de développer une néoplasie du côlon |
WO2015003114A1 (fr) * | 2013-07-05 | 2015-01-08 | University Of Washington Through Its Center For Commercialization | Anticorps monoclonal neutralisant la protéine mic soluble pour le traitement du cancer |
US10023651B2 (en) | 2014-04-18 | 2018-07-17 | The Research Foundation For The State University Of New York | Humanized anti-TF-antigen antibodies |
JP6740135B2 (ja) * | 2014-04-18 | 2020-08-12 | ザ リサーチ ファウンデイション フォー ザ ステイト ユニバーシティー オブ ニューヨーク | ヒト化抗−tf−抗原抗体 |
WO2016066671A1 (fr) | 2014-10-29 | 2016-05-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédé pour traiter des cancers résistants à l'aide d'inhibiteurs de la progastrine |
AU2016324021A1 (en) * | 2015-09-15 | 2018-04-12 | The Scripps Research Institute | Antibodies for generating anti-inflammatory macrophage and related uses |
CN108780091A (zh) * | 2015-12-31 | 2018-11-09 | 普莱戈斯瑞恩癌症有限责任公司 | 用于检测和治疗卵巢癌的组合物和方法 |
AU2017204685B2 (en) * | 2015-12-31 | 2022-10-13 | Progastrine Et Cancers S.À R.L. | Compositions and methods for detecting and treating gastric cancer |
MA43550A (fr) * | 2015-12-31 | 2018-11-07 | Syncerus S A R L | Compositions et procédés d'évaluation du risque d'apparition d'un cancer |
WO2018178364A1 (fr) * | 2017-03-30 | 2018-10-04 | Progastrine Et Cancers S.À R.L. | Compositions et méthodes de traitement du cancer du poumon |
EP3601347B1 (fr) * | 2017-03-30 | 2021-11-03 | Progastrine et Cancers S.à r.l. | Compositions et procédés pour détecter et traiter le cancer de la prostate utilisant une molécule de liaison à la progastrine |
EP3720879B1 (fr) * | 2017-12-05 | 2022-05-11 | Progastrine et Cancers S.à r.l. | Thérapie de combinaison comprenant des anticorps anti-prostaglandine et immunothérapie pour traiter cancer |
TW201927343A (zh) | 2017-12-08 | 2019-07-16 | 瑞士商Ecs生物識別系統有限公司 | 癌症診斷中之經放射標記的前胃泌激素 |
TW201940881A (zh) | 2018-01-26 | 2019-10-16 | 瑞士商Ecs前胃泌激素公司 | 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術 |
WO2019166499A1 (fr) * | 2018-02-27 | 2019-09-06 | Ecs-Progastrin Sa | Progastrine en tant que biomarqueur pour l'immunothérapie |
TWI793238B (zh) * | 2018-12-27 | 2023-02-21 | 偉喬生醫股份有限公司 | 體外檢測生物樣品之胃源性蛋白的方法及套組 |
CN115785273B (zh) * | 2021-09-10 | 2023-10-31 | 东莞市朋志生物科技有限公司 | 一种抗胃蛋白酶原i的抗体及其应用 |
CN116143920A (zh) * | 2022-12-30 | 2023-05-23 | 南京岚煜生物科技有限公司 | 胃泌素17的单克隆抗体及其细胞株的制备方法和应用 |
CN117567611B (zh) * | 2023-11-22 | 2024-05-14 | 艾维可生物科技有限公司 | 抗成熟型胃泌素17的单克隆抗体及其应用 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
EP0463151B1 (fr) | 1990-01-12 | 1996-06-12 | Cell Genesys, Inc. | Generation d'anticorps xenogeniques |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
EP0519596B1 (fr) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | Procédé pour réduire l'immunogénicité des domaines variables d'anticorps |
MX9204374A (es) | 1991-07-25 | 1993-03-01 | Idec Pharma Corp | Anticuerpo recombinante y metodo para su produccion. |
ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
AU3328493A (en) | 1991-12-17 | 1993-07-19 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
EP2567974A3 (fr) * | 2004-09-22 | 2013-05-22 | Cancer Advances, Inc., | Anticorps monoclonaux contre la progastrine |
ES2727306T3 (es) * | 2006-05-22 | 2019-10-15 | Inst Nat Sante Rech Med | Inhibidores de progastrina en el tratamiento del cáncer de colon |
US7854932B2 (en) | 2006-12-19 | 2010-12-21 | The Board Of Regents Of The University Of Texas System | Immunogenic compositions comprising progastrin and uses thereof |
EP2337795A2 (fr) * | 2008-10-01 | 2011-06-29 | Dako Denmark A/S | Multimères de mhc dans des vaccins et la surveillance immunitaire contre le cancer |
AR078659A1 (es) * | 2009-10-16 | 2011-11-23 | Biorealites S A | Anticuerpos monoclonales contra progastrina humana y sus usos |
-
2010
- 2010-10-15 AR ARP100103784A patent/AR078659A1/es active IP Right Grant
- 2010-10-15 CN CN201410752851.1A patent/CN104628857A/zh active Pending
- 2010-10-15 AP AP2012006262A patent/AP2012006262A0/xx unknown
- 2010-10-15 PL PL18185172.6T patent/PL3421493T3/pl unknown
- 2010-10-15 PT PT10768878T patent/PT2488551T/pt unknown
- 2010-10-15 CA CA2777691A patent/CA2777691C/fr active Active
- 2010-10-15 UA UAA201205759A patent/UA106771C2/uk unknown
- 2010-10-15 AU AU2010306119A patent/AU2010306119A1/en not_active Abandoned
- 2010-10-15 MX MX2012004400A patent/MX351635B/es active IP Right Grant
- 2010-10-15 EP EP10768878.0A patent/EP2488551B1/fr active Active
- 2010-10-15 SG SG10201704933PA patent/SG10201704933PA/en unknown
- 2010-10-15 GE GEAP201012707A patent/GEP201706604B/en unknown
- 2010-10-15 DK DK10768878.0T patent/DK2488551T3/en active
- 2010-10-15 JP JP2012533531A patent/JP5985987B2/ja active Active
- 2010-10-15 NZ NZ701709A patent/NZ701709A/en unknown
- 2010-10-15 BR BR112012008818-1A patent/BR112012008818B1/pt active IP Right Grant
- 2010-10-15 PE PE2012000434A patent/PE20121649A1/es active IP Right Grant
- 2010-10-15 EP EP18185172.6A patent/EP3421493B1/fr active Active
- 2010-10-15 CN CN201080057237.3A patent/CN102791735B/zh active Active
- 2010-10-15 NZ NZ599971A patent/NZ599971A/en unknown
- 2010-10-15 EA EA201791876A patent/EA201791876A1/ru unknown
- 2010-10-15 TW TW099135321A patent/TWI537002B/zh active
- 2010-10-15 PL PL10768878T patent/PL2488551T3/pl unknown
- 2010-10-15 KR KR1020157017085A patent/KR101640520B1/ko active IP Right Grant
- 2010-10-15 LT LTEP10768878.0T patent/LT2488551T/lt unknown
- 2010-10-15 KR KR1020127012677A patent/KR20120091221A/ko active Application Filing
- 2010-10-15 IN IN3348DEN2012 patent/IN2012DN03348A/en unknown
- 2010-10-15 EA EA201200597A patent/EA029271B1/ru not_active IP Right Cessation
- 2010-10-15 ES ES18185172T patent/ES2973217T3/es active Active
- 2010-10-15 US US12/906,041 patent/US9611320B2/en active Active
- 2010-10-15 WO PCT/EP2010/006329 patent/WO2011045080A2/fr active Application Filing
- 2010-10-15 ES ES10768878.0T patent/ES2690943T3/es active Active
- 2010-10-15 RS RS20181241A patent/RS57966B1/sr unknown
- 2010-10-15 SI SI201031788T patent/SI2488551T1/sl unknown
-
2012
- 2012-04-03 IL IL219019A patent/IL219019B/en active IP Right Grant
- 2012-04-04 TN TNP2012000159A patent/TN2012000159A1/en unknown
- 2012-04-11 CL CL2012000914A patent/CL2012000914A1/es unknown
- 2012-04-12 ZA ZA2012/02642A patent/ZA201202642B/en unknown
- 2012-04-13 CR CR20120184A patent/CR20120184A/es unknown
- 2012-04-13 HN HN2012000708A patent/HN2012000708A/es unknown
- 2012-04-13 NI NI201200054A patent/NI201200054A/es unknown
- 2012-04-13 EC ECSP12011796 patent/ECSP12011796A/es unknown
- 2012-04-16 GT GT201200114A patent/GT201200114A/es unknown
- 2012-04-16 CU CUP2012000060A patent/CU24196B1/es active IP Right Grant
- 2012-05-11 MA MA34864A patent/MA33747B1/fr unknown
-
2013
- 2013-05-20 HK HK13105899.6A patent/HK1178183A1/zh unknown
-
2015
- 2015-03-04 JP JP2015042849A patent/JP6272793B2/ja active Active
-
2017
- 2017-03-06 US US15/451,275 patent/US10377821B2/en active Active
- 2017-03-06 US US15/451,280 patent/US10385126B2/en active Active
- 2017-03-06 US US15/451,253 patent/US10385124B2/en active Active
- 2017-03-06 US US15/451,268 patent/US10385125B2/en active Active
- 2017-06-21 JP JP2017121372A patent/JP2017212992A/ja active Pending
- 2017-08-15 IL IL254004A patent/IL254004B2/en unknown
-
2018
- 2018-10-11 HR HRP20181645TT patent/HRP20181645T1/hr unknown
- 2018-10-22 CY CY181101081T patent/CY1120913T1/el unknown
-
2019
- 2019-06-28 US US16/456,328 patent/US11299542B2/en active Active
-
2022
- 2022-03-07 US US17/687,909 patent/US20220195035A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA33747B1 (fr) | Anticorps monoclonaux diriges contre la progastrine et leurs utilisations | |
WO2004067570A3 (fr) | Diagnostic et traitement du cancer de la prostate | |
EP4357783A3 (fr) | Système et procédés hautement sensibles pour l'analyse de troponine | |
WO2010056337A3 (fr) | Procédés et systèmes d'utilisation d'exosomes pour déterminer des phénotypes | |
MA32561B1 (fr) | Anticorps neutralisant le cytomegalovirus humain et leurs utilisations | |
MA33256B1 (fr) | Anticorps et immunoconjugués anti-fcrh5 et procédés d'utilisation | |
WO2007035651A3 (fr) | Bio-essai de diagnostic du lupus erythemateux systemique | |
WO2010027903A3 (fr) | Diagnostic du cancer du poumon | |
WO2011015602A3 (fr) | Biomarqueurs du cancer du poumon | |
UA106194C2 (ru) | Диагностика и лечение рака с применением антитела к ereg | |
WO2011047033A3 (fr) | Biomarqueur d'identification de cellules tumorales de mélanome | |
EP2566983A4 (fr) | Analyse en série de biomarqueurs à des fins de diagnostic d'une maladie | |
EP1934377A4 (fr) | Procédés et compositions permettant d'identifier des biomarqueurs utiles au diagnostic et/ou au traitement d'états biologiques | |
ATE548050T1 (de) | Diagnoseverfahren | |
MA30393B1 (fr) | Procede de traitement, de diagnostic ou de detection du cancer | |
WO2007084397A3 (fr) | Méthode de traitement de slpi par chymase | |
NZ608316A (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | |
MX2009010751A (es) | Composiciones y metodos de deteccion. | |
AU2010202926B2 (en) | Markers and methods relating to the assessment of Alzheimer's disease | |
WO2010031749A9 (fr) | Compositions et procédés pour détecter tlr3 | |
WO2010044506A3 (fr) | Anticorps humain spécifique de tmprss4 | |
MA34291B1 (fr) | Compositions et méthodes de diagnostic et de traitement d'une tumeur | |
WO2007019276A3 (fr) | Detection quantitative de plomb dans de l'eau | |
BR112015021507A2 (pt) | métodos e composições para o diagnóstico de pré-eclampsia | |
NZ601643A (en) | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |