MA33063B1 - Complexe d'hydrohalogenure d'agomelatine et procede de preparation de celui-ci - Google Patents
Complexe d'hydrohalogenure d'agomelatine et procede de preparation de celui-ciInfo
- Publication number
- MA33063B1 MA33063B1 MA34120A MA34120A MA33063B1 MA 33063 B1 MA33063 B1 MA 33063B1 MA 34120 A MA34120 A MA 34120A MA 34120 A MA34120 A MA 34120A MA 33063 B1 MA33063 B1 MA 33063B1
- Authority
- MA
- Morocco
- Prior art keywords
- hydrohalogenide
- agomelatin
- preparing
- complex
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B7/00—Halogens; Halogen acids
- C01B7/01—Chlorine; Hydrogen chloride
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B7/00—Halogens; Halogen acids
- C01B7/09—Bromine; Hydrogen bromide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE UN COMPLEXE D'HYDROHALOGÉNURE D'AGOMÉLATINE ET UN PROCÉDÉ DE PRÉPARATION DE CELUI-CI. COMPARÉ À L'AGOMÉLATINE, UN COMPLEXE D'HYDROHALOGÉNURE D'AGOMÉLATINE OBTENU PAR LE PRÉSENT PROCÉDÉ A UNE SOLUBILITÉ AMÉLIORÉE, ET EST ADAPTÉ À L'APPLICATION NÉCESSAIRE DE PRÉPARATION DE PRODUITS FINIS DE MÉDICAMENTS. DE PLUS, LE PRODUIT A UNE BONNE STABILITÉ ET UNE PURETÉ ÉLEVÉE. LE PROCÉDÉ DE PRÉPARATION EST SIMPLE ET COMMODE ET LE PRODUIT AYANT UNE PURETÉ ÉLEVÉ PEUT ÊTRE OBTENU SANS OPÉRATIONS SPÉCIALES.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009100467821A CN101481321B (zh) | 2009-02-27 | 2009-02-27 | 阿戈美拉汀卤化氢复合物及其制备方法 |
PCT/CN2010/070780 WO2010097052A1 (fr) | 2009-02-27 | 2010-02-26 | Complexe d'hydrohalogénure d'agomélatine et procédé de préparation de celui-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
MA33063B1 true MA33063B1 (fr) | 2012-02-01 |
Family
ID=40878634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA34120A MA33063B1 (fr) | 2009-02-27 | 2010-02-26 | Complexe d'hydrohalogenure d'agomelatine et procede de preparation de celui-ci |
Country Status (36)
Country | Link |
---|---|
US (1) | US8524949B2 (fr) |
EP (1) | EP2418195B1 (fr) |
JP (1) | JP5426693B2 (fr) |
KR (1) | KR101284202B1 (fr) |
CN (1) | CN101481321B (fr) |
AP (1) | AP3048A (fr) |
AU (1) | AU2010217082B2 (fr) |
BR (1) | BRPI1008767B1 (fr) |
CA (1) | CA2753449C (fr) |
CL (1) | CL2011002090A1 (fr) |
CO (1) | CO6420335A2 (fr) |
CR (1) | CR20110446A (fr) |
CU (1) | CU20110163A7 (fr) |
CY (1) | CY1117100T1 (fr) |
DK (1) | DK2418195T3 (fr) |
EA (1) | EA021939B1 (fr) |
EC (1) | ECSP11011290A (fr) |
ES (1) | ES2530730T3 (fr) |
GE (1) | GEP20156221B (fr) |
HN (1) | HN2011002291A (fr) |
HR (1) | HRP20150072T1 (fr) |
IL (1) | IL214682A (fr) |
MA (1) | MA33063B1 (fr) |
MX (1) | MX2011008946A (fr) |
MY (1) | MY154015A (fr) |
NI (1) | NI201100163A (fr) |
NZ (1) | NZ594773A (fr) |
PE (1) | PE20120652A1 (fr) |
PL (1) | PL2418195T3 (fr) |
PT (1) | PT2418195E (fr) |
RS (1) | RS53751B1 (fr) |
SG (1) | SG173691A1 (fr) |
SI (1) | SI2418195T1 (fr) |
UA (1) | UA97619C2 (fr) |
WO (1) | WO2010097052A1 (fr) |
ZA (1) | ZA201106048B (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102106806B (zh) * | 2009-12-29 | 2013-04-17 | 上海中西制药有限公司 | 一种固体制剂的制备方法及所得固体制剂 |
CN102190594A (zh) | 2010-03-17 | 2011-09-21 | 上海医药工业研究院 | 阿戈美拉汀氯化氢水合物及其制备方法 |
CN102190595A (zh) * | 2010-03-17 | 2011-09-21 | 上海医药工业研究院 | 阿戈美拉汀溴化氢水合物及其制备方法 |
CN101870662B (zh) * | 2010-05-21 | 2013-03-20 | 中山大学 | 结晶型阿戈美拉汀溶剂化物及其制备方法 |
WO2012046253A2 (fr) * | 2010-10-08 | 2012-04-12 | Msn Laboratories Limited | Procédé de préparation de n-[2- (7-méthoxy-l-naphthyl) éthyl] acétamide et ses nouvelles formes cristallines |
RS52982B (en) * | 2011-04-28 | 2014-02-28 | Zentiva, K.S. | PHARMACEUTICAL ACCEPTIBLE CO-CRYSTALS OF N- [2- (7-METHOXY-1-NAPHTHYL) ACETAMIDE AND THEIR MAKING PROCEDURES |
EP2551257A1 (fr) * | 2011-07-28 | 2013-01-30 | Laboratorios Del. Dr. Esteve, S.A. | Co-cristaux d'agomélatine avec formeurs de co-cristaux |
FR2978916B1 (fr) | 2011-08-10 | 2013-07-26 | Servier Lab | Composition pharmaceutique solide pour administration buccale d'agomelatine |
CN102702041B (zh) * | 2012-05-14 | 2013-08-14 | 上海右手医药科技开发有限公司 | 阿戈美拉汀苯磺酸类复合物及其制备方法 |
CN102702008B (zh) * | 2012-06-03 | 2014-05-28 | 上海右手医药科技开发有限公司 | 阿戈美拉汀硫酸复合物及其制备方法 |
US9409857B2 (en) | 2012-05-14 | 2016-08-09 | Shanghai Righthand Pharmtech, Co., Ltd. | Agomelatine sulfuric acid complex, and preparation method and application thereof |
CN102718675B (zh) * | 2012-06-07 | 2015-03-25 | 上海右手医药科技开发有限公司 | 阿戈美拉汀甲磺酸复合物及其制备方法 |
EP2743255B1 (fr) * | 2012-12-17 | 2016-06-22 | Dr. Reddy's Laboratories Ltd. | Cocristal d'agomélatine avec de l'acide phosphorique |
WO2014096373A1 (fr) | 2012-12-21 | 2014-06-26 | Laboratorios Lesvi, S. L. | Procédé de préparation de n-(2-(7-méthoxy-1-naphtalényl)éthyl)acétamide et de formes solides de celui-ci |
FR3001894A1 (fr) | 2013-02-08 | 2014-08-15 | Servier Lab | Composition pharmaceutique solide pour administration buccale d'agomelatine |
CN105473547B (zh) * | 2013-07-29 | 2019-10-15 | 法国施维雅药厂 | 阿戈美拉汀和磺酸的新复合物、其制备方法和包含其的药物组合物 |
HUE044798T2 (hu) * | 2013-07-31 | 2019-11-28 | Servier Lab | Agomelatin és p-toluol-szulfonsav kokristályai, eljárás elõállításukra, és ezeket tartalmazó gyógyszerészeti készítmények |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2778662B1 (fr) * | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2795326B1 (fr) * | 1999-06-28 | 2001-08-31 | Adir | Composition pharmaceutique solide thermoformable a liberation controlee |
CN100475789C (zh) | 2002-05-24 | 2009-04-08 | 拜尔农作物科学股份公司 | 制备烷硫基胺衍生物的方法 |
EP1752440A4 (fr) * | 2004-01-15 | 2007-04-18 | Tosoh Corp | Compose amine comprenant un groupe fluorene en tant que structure, procede de production dudit compose amine, et utilisation de ce dernier |
FR2866335B1 (fr) * | 2004-02-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
FR2889523B1 (fr) * | 2005-08-03 | 2007-12-28 | Servier Lab | Nouvelle forme cristalline v de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2899472B1 (fr) * | 2006-04-07 | 2008-09-12 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee |
-
2009
- 2009-02-27 CN CN2009100467821A patent/CN101481321B/zh not_active Expired - Fee Related
-
2010
- 2010-02-26 PT PT107458366T patent/PT2418195E/pt unknown
- 2010-02-26 JP JP2011551399A patent/JP5426693B2/ja active Active
- 2010-02-26 ES ES10745836T patent/ES2530730T3/es active Active
- 2010-02-26 PL PL10745836T patent/PL2418195T3/pl unknown
- 2010-02-26 DK DK10745836T patent/DK2418195T3/en active
- 2010-02-26 EP EP10745836.6A patent/EP2418195B1/fr active Active
- 2010-02-26 MX MX2011008946A patent/MX2011008946A/es active IP Right Grant
- 2010-02-26 SG SG2011058542A patent/SG173691A1/en unknown
- 2010-02-26 CA CA2753449A patent/CA2753449C/fr active Active
- 2010-02-26 NZ NZ594773A patent/NZ594773A/xx not_active IP Right Cessation
- 2010-02-26 UA UAA201111232A patent/UA97619C2/ru unknown
- 2010-02-26 US US13/138,511 patent/US8524949B2/en active Active
- 2010-02-26 MA MA34120A patent/MA33063B1/fr unknown
- 2010-02-26 KR KR1020117021812A patent/KR101284202B1/ko active IP Right Grant
- 2010-02-26 AU AU2010217082A patent/AU2010217082B2/en not_active Ceased
- 2010-02-26 MY MYPI2011003884A patent/MY154015A/en unknown
- 2010-02-26 BR BRPI1008767-2A patent/BRPI1008767B1/pt not_active IP Right Cessation
- 2010-02-26 SI SI201030872T patent/SI2418195T1/sl unknown
- 2010-02-26 PE PE2011001512A patent/PE20120652A1/es not_active Application Discontinuation
- 2010-02-26 GE GEAP201012388A patent/GEP20156221B/en unknown
- 2010-02-26 WO PCT/CN2010/070780 patent/WO2010097052A1/fr active Application Filing
- 2010-02-26 EA EA201101208A patent/EA021939B1/ru unknown
- 2010-02-26 RS RS20150040A patent/RS53751B1/en unknown
- 2010-02-26 AP AP2011005845A patent/AP3048A/xx active
-
2011
- 2011-08-16 IL IL214682A patent/IL214682A/en active IP Right Grant
- 2011-08-17 ZA ZA2011/06048A patent/ZA201106048B/en unknown
- 2011-08-19 CR CR20110446A patent/CR20110446A/es unknown
- 2011-08-23 CU CU20110163A patent/CU20110163A7/es unknown
- 2011-08-26 CL CL2011002090A patent/CL2011002090A1/es unknown
- 2011-08-26 EC EC2011011290A patent/ECSP11011290A/es unknown
- 2011-08-26 HN HN2011002291A patent/HN2011002291A/es unknown
- 2011-08-26 CO CO11109274A patent/CO6420335A2/es not_active Application Discontinuation
- 2011-08-26 NI NI201100163A patent/NI201100163A/es unknown
-
2015
- 2015-01-20 HR HRP20150072AT patent/HRP20150072T1/hr unknown
- 2015-01-22 CY CY20151100070T patent/CY1117100T1/el unknown
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