MA30924B1 - Analogues de pyrazoles - Google Patents

Analogues de pyrazoles

Info

Publication number
MA30924B1
MA30924B1 MA31925A MA31925A MA30924B1 MA 30924 B1 MA30924 B1 MA 30924B1 MA 31925 A MA31925 A MA 31925A MA 31925 A MA31925 A MA 31925A MA 30924 B1 MA30924 B1 MA 30924B1
Authority
MA
Morocco
Prior art keywords
compounds
pyrazoles
analogues
disorders
conditions
Prior art date
Application number
MA31925A
Other languages
English (en)
Inventor
Matthew J Graneto
Todd Michael Maddux
Jaime L Masferrer
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA30924B1 publication Critical patent/MA30924B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION PORTE SUR DES COMPOSÉS DE FORMULE (I) DANS LAQUELLE R1 EST F OU H, OU UN DE LEURS SELS OU SOLVATES PHARMACEUTIQUEMENT ACCEPTABLES, ET SUR LEURS PROCÉDÉS DE PRÉPARATION, LES INTERMÉDIAIRES UTILISÉES DANS LEUR PRÉPARATION, DES COMPOSITIONS LES CONTENANT ET LEURS UTILISATIONS. LESDITS COMPOSÉS S'AVÈRENT UTILES DANS DE NOMBREUSES MALADIES, TROUBLES ET ÉTATS, ET EN PARTICULIER DANS DES MALADIES TROUBLES ET ÉTATS ALLERGIQUES ET RESPIRATOIRES.
MA31925A 2006-11-27 2009-05-27 Analogues de pyrazoles MA30924B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86733706P 2006-11-27 2006-11-27

Publications (1)

Publication Number Publication Date
MA30924B1 true MA30924B1 (fr) 2009-11-02

Family

ID=39226772

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31925A MA30924B1 (fr) 2006-11-27 2009-05-27 Analogues de pyrazoles

Country Status (32)

Country Link
US (1) US7772269B2 (fr)
EP (1) EP2097407A1 (fr)
JP (1) JP4469924B2 (fr)
KR (1) KR20090074264A (fr)
CN (1) CN101541790A (fr)
AP (1) AP2009004849A0 (fr)
AR (1) AR063924A1 (fr)
AU (1) AU2007327004A1 (fr)
BR (1) BRPI0718672A2 (fr)
CA (1) CA2667566C (fr)
CL (1) CL2007003403A1 (fr)
CO (1) CO6180447A2 (fr)
CR (1) CR10745A (fr)
CU (1) CU23801B7 (fr)
DO (1) DOP2009000121A (fr)
EA (1) EA016588B1 (fr)
EC (1) ECSP099328A (fr)
GE (1) GEP20125386B (fr)
GT (1) GT200700104A (fr)
HN (1) HN2007000505A (fr)
IL (1) IL198412A0 (fr)
MA (1) MA30924B1 (fr)
MX (1) MX2009005526A (fr)
NO (1) NO20092413L (fr)
NZ (1) NZ576376A (fr)
PE (1) PE20081299A1 (fr)
RS (1) RS20090211A (fr)
TN (1) TN2009000205A1 (fr)
TW (1) TW200831495A (fr)
UA (1) UA92833C2 (fr)
UY (1) UY30743A1 (fr)
WO (1) WO2008065493A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009069044A1 (fr) 2007-11-26 2009-06-04 Pfizer Inc. Dérivés de pyrazole comme inhibiteurs de 5-lo
EP2151450A1 (fr) * 2008-07-29 2010-02-10 Sandoz AG Procédé de préparation d'oligopeptides cycliques microbiologiques
EP2563359A1 (fr) * 2010-04-30 2013-03-06 Allergan, Inc. Nouveau traitement pour la dégénérescence maculaire liée à l'âge et la maladie ischémique oculaire associée à l'activation du complément par le ciblage de la 5-lipoxygénase
TWI527809B (zh) * 2011-01-24 2016-04-01 百靈佳殷格翰國際股份有限公司 作為ｃｒｔｈ２拮抗劑之吡唑化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
PL175987B1 (pl) 1993-06-14 1999-03-31 Pfizer Nowe imidazolowe inhibitory lipoksygenazy
US5883106A (en) 1994-10-18 1999-03-16 Pfizer Inc. 5-lipoxygenase inhibitors
JP3400392B2 (ja) * 1994-10-18 2003-04-28 ファイザー製薬株式会社 ５−リポキシゲナーゼ阻害剤及び新規医薬組成物
SK281577B6 (sk) * 1994-10-18 2001-05-10 Pfizer Inc. Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze
US6037355A (en) 1995-09-18 2000-03-14 Pfizer Inc Imidazole lipoxygenase inhibitors
US6194585B1 (en) * 1998-12-22 2001-02-27 Pfizer Inc. Process for preparing 5-lipoxygenase inhibitors
JP2001100682A (ja) * 1999-09-28 2001-04-13 Sanyo Electric Co Ltd サインシステム
JP2001100686A (ja) * 1999-09-28 2001-04-13 Hitachi Kokusai Electric Inc 表示データ取込方法及び比較検査装置

Also Published As

Publication number Publication date
TN2009000205A1 (fr) 2010-10-18
UA92833C2 (en) 2010-12-10
DOP2009000121A (es) 2009-06-15
NO20092413L (no) 2009-07-20
CU23801B7 (es) 2012-03-15
NZ576376A (en) 2011-02-25
JP2010511601A (ja) 2010-04-15
HN2007000505A (es) 2010-06-09
PE20081299A1 (es) 2008-09-17
US20080125474A1 (en) 2008-05-29
AP2009004849A0 (en) 2009-06-30
AR063924A1 (es) 2009-02-25
CA2667566C (fr) 2012-01-03
CL2007003403A1 (es) 2008-07-04
EP2097407A1 (fr) 2009-09-09
WO2008065493A1 (fr) 2008-06-05
AU2007327004A1 (en) 2008-06-05
EA016588B1 (ru) 2012-06-29
ECSP099328A (es) 2009-06-30
MX2009005526A (es) 2009-06-05
CO6180447A2 (es) 2010-07-19
UY30743A1 (es) 2008-07-03
TW200831495A (en) 2008-08-01
US7772269B2 (en) 2010-08-10
RS20090211A (en) 2010-10-31
BRPI0718672A2 (pt) 2013-11-26
GT200700104A (es) 2011-04-13
CR10745A (es) 2009-05-22
EA200970422A1 (ru) 2009-12-30
CN101541790A (zh) 2009-09-23
CU20090083A7 (es) 2011-09-21
GEP20125386B (en) 2012-01-25
JP4469924B2 (ja) 2010-06-02
KR20090074264A (ko) 2009-07-06
CA2667566A1 (fr) 2008-06-05
IL198412A0 (en) 2010-02-17

Similar Documents

Publication Publication Date Title
MA30289B1 (fr) Dérivés d'amines
TNSN07022A1 (fr) Derives de pyridine
MA29170B1 (fr) Derives puriniques agissant comme des agonistes du recepteur a2a
TN2009000138A1 (fr) Biaryl-ether-urees
TN2011000316A1 (fr) Derives de sulfonamides
MA29926B1 (fr) Derives de pyrazine
MA29772B1 (fr) Benzimidazoles substitues et procedes de preparation
TN2009000450A1 (fr) Derives de pyridine
MA32070B1 (fr) Dérivés hétérocycliques réunis par fusion et procédés d'utilisation associés
MA29791B1 (fr) Composes therapeutiques.
TN2009000112A1 (fr) Derives de sulfonamides servant d'agonistes adrenergiques et d'antagonistes muscariniques
MA31952B1 (fr) Pyrrolopyrimidines et pyrrolopyridines
MA30911B1 (fr) Nouveaux derives de sulfonamide en tant qu'antagonistes de bradykinine
MA28437B1 (fr) Composes et leurs procedes d'utilisation
MA31894B1 (fr) Composes organiques
MA27009A1 (fr) Derives de pyrazole pour le traitement d'une infection par le vih
MA31311B1 (fr) Dérivés d'indazole substitués par oxadiazole, destinés à être utilisés comme agonistes de la sphingosine 1-phosphate (s1p)
TN2010000175A1 (fr) Piperidino-dihydrothienopyrimidines substituees
MA30694B1 (fr) Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique.
MA27774A1 (fr) Inhibiteurs de phosphatidylinositol 3-kinase
MY143390A (en) Sulfonamide derivatives for the treatment of diseases.
MA31283B1 (fr) Produits dérivés de 2,3-dihydroimidazo[1,2-c]quinazoline substitués, utiles pour le traitement de troubles hyperlifératifs et de maladies associées à une angiogénèse
MA30405B1 (fr) Derives de 4-benzylphtalazinone substitues en 2 en tant qu'antagonistes des histamines hl et h3
TN2009000033A1 (fr) Derives de pyrazole servant d'inhibiteurs du cytochrome p450
TNSN08137A1 (fr) Derives de carboxamides servant d'antagonistes des recepteurs muscariniques