MA29524B1 - Anticorps diriges contre la myostatine - Google Patents
Anticorps diriges contre la myostatineInfo
- Publication number
- MA29524B1 MA29524B1 MA30410A MA30410A MA29524B1 MA 29524 B1 MA29524 B1 MA 29524B1 MA 30410 A MA30410 A MA 30410A MA 30410 A MA30410 A MA 30410A MA 29524 B1 MA29524 B1 MA 29524B1
- Authority
- MA
- Morocco
- Prior art keywords
- myostatin
- antibodies
- human antibodies
- relates
- directed against
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Abstract
L'invention concerne des anticorps parmi lesquels figurent des anticorps humains, et des parties de liaison à l'antigène correspondantes, qui se lient à la myostatine, et dont la fonction est d'inhiber la myostatine. L'invention concerne également des anticorps humains dirigés contre la myostatine, ainsi que des parties de liaison à l'antigène correspondantes. Cette invention se rapporte aussi à des anticorps qui sont chimériques, bispécifiques, dérivatisés, monocaténaires, ou qui se présentent sous la forme de parties de protéines de fusion. L'invention concerne par ailleurs des immunoglobulines isolées à chaîne lourde et à chaîne légère qui sont dérivées d'anticorps humains dirigés contre la myostatine, et des molécules codant ces immunoglobulines. L'invention concerne en outre des procédés pour produire des anticorps humains dirigés contre la myostatine, des compositions contenant des anticorps, et des procédés d'utilisation de ces anticorps et de ces compositions à des fins de diagnostic et de traitement. L'invention concerne également des procédés de thérapie génique faisant appel à des molécules d'acide nucléique codant les molécules d'immunoglobuline à chaîne lourde et/ou à chaîne légère qui comprennent les anticorps humains dirigés contre la myostatine. La présente invention concerne également des animaux ou des plantes transgéniques comprenant les molécules d'acide nucléique selon l'invention.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67493305P | 2005-04-25 | 2005-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA29524B1 true MA29524B1 (fr) | 2008-06-02 |
Family
ID=37215358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30410A MA29524B1 (fr) | 2005-04-25 | 2007-11-22 | Anticorps diriges contre la myostatine |
Country Status (23)
Country | Link |
---|---|
US (2) | US7807159B2 (fr) |
EP (2) | EP2295466A3 (fr) |
JP (1) | JP2008539241A (fr) |
KR (1) | KR20080011403A (fr) |
CN (1) | CN101272802A (fr) |
AP (1) | AP2007004243A0 (fr) |
AR (1) | AR053067A1 (fr) |
AU (1) | AU2006239860B2 (fr) |
BR (1) | BRPI0610248A2 (fr) |
CA (1) | CA2605723A1 (fr) |
CR (1) | CR9466A (fr) |
DO (1) | DOP2006000093A (fr) |
EA (2) | EA015534B1 (fr) |
IL (1) | IL186739A (fr) |
MA (1) | MA29524B1 (fr) |
MX (1) | MX2007013217A (fr) |
NL (3) | NL1031674C2 (fr) |
NO (1) | NO20076061L (fr) |
PE (1) | PE20061395A1 (fr) |
TN (1) | TNSN07394A1 (fr) |
TW (1) | TW200724548A (fr) |
WO (1) | WO2006116269A2 (fr) |
ZA (1) | ZA200709291B (fr) |
Families Citing this family (105)
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CA2722466A1 (fr) | 2008-04-29 | 2009-11-05 | Tariq Ghayur | Immunoglobulines a double domaine variable et utilisations |
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- 2006-04-24 US US11/410,886 patent/US7807159B2/en active Active
- 2006-04-24 WO PCT/US2006/015407 patent/WO2006116269A2/fr active Application Filing
- 2006-04-24 JP JP2008508984A patent/JP2008539241A/ja active Pending
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