MA29213B1 - Quinolones a substitution macrolones - amino - Google Patents

Quinolones a substitution macrolones - amino

Info

Publication number
MA29213B1
MA29213B1 MA29930A MA29930A MA29213B1 MA 29213 B1 MA29213 B1 MA 29213B1 MA 29930 A MA29930 A MA 29930A MA 29930 A MA29930 A MA 29930A MA 29213 B1 MA29213 B1 MA 29213B1
Authority
MA
Morocco
Prior art keywords
macrolones
quinolones
substitution
amino
medicine
Prior art date
Application number
MA29930A
Other languages
English (en)
Inventor
Desmond John Best
John Stephen Elder
Andrea Fajdetic
Andrew Keith Forrest
Robert John Sheppard
Original Assignee
Glaxosmithkline Zagreb
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb, Glaxo Group Ltd filed Critical Glaxosmithkline Zagreb
Publication of MA29213B1 publication Critical patent/MA29213B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSÉS DE FORMULE (I) OU DES DÉRIVÉS ACCEPTABLES SUR LE PLAN PHARMACEUTIQUE DE CEUX-CI POSSÉDANT UNE ACTIVITÉ ANTI-MICROBIENNE, DES PROCÉDÉS DE PRÉPARATION DE CEUX-CI, DES COMPOSTIONS RENFERMANT CEUX-CI ET L'UTILISATION DE CEUX-CI EN MÉDECINE.
MA29930A 2004-11-11 2007-05-22 Quinolones a substitution macrolones - amino MA29213B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0424959A GB0424959D0 (en) 2004-11-11 2004-11-11 Novel compounds

Publications (1)

Publication Number Publication Date
MA29213B1 true MA29213B1 (fr) 2008-02-01

Family

ID=33523587

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29930A MA29213B1 (fr) 2004-11-11 2007-05-22 Quinolones a substitution macrolones - amino

Country Status (19)

Country Link
US (2) US7718621B2 (fr)
EP (1) EP1824870A1 (fr)
JP (1) JP2008519788A (fr)
KR (1) KR20070085919A (fr)
CN (1) CN101098881A (fr)
AR (1) AR053311A1 (fr)
AU (1) AU2005303961A1 (fr)
BR (1) BRPI0517792A (fr)
CA (1) CA2587413A1 (fr)
GB (1) GB0424959D0 (fr)
IL (1) IL182978A0 (fr)
MA (1) MA29213B1 (fr)
MX (1) MX2007005776A (fr)
NO (1) NO20072939L (fr)
PE (1) PE20061137A1 (fr)
RU (1) RU2007121581A (fr)
TW (1) TW200630378A (fr)
WO (1) WO2006050942A1 (fr)
ZA (1) ZA200703603B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
EP1879904A1 (fr) * 2005-05-10 2008-01-23 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Macrolides a liaison aminee 4" destines au traitement d'infections microbiennes
WO2007054296A1 (fr) * 2005-11-09 2007-05-18 Glaxo Group Limited Macrolones
PE20070802A1 (es) * 2005-11-09 2007-10-19 Glaxo Group Ltd Derivados de eritromicina 4''-sustituidos como agentes antimicrobianos
EP2201010B1 (fr) 2007-09-14 2013-11-06 Vertex Pharmaceuticals Incorporated Modulateurs du régulateur de la conductance transmembranaire de la mucoviscidose
CA2703475A1 (fr) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Procede pour la preparation d'agents antibacteriens macrolides
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides
CN102245195B (zh) 2008-10-24 2016-01-13 森普拉制药公司 使用含***的大环内酯的生物防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (fr) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Méthodes de traitement du paludisme, de la tuberculose et des maladies à complexe mycobacterium avium (mac)
AU2011255464C1 (en) 2010-05-20 2017-02-23 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
EP2613630A4 (fr) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc Fluorocétolides formant des liaisons hydrogène pour traiter les maladies
EP2830632A4 (fr) 2012-03-27 2015-10-21 Cempra Pharmaceuticals Inc Formulations parentérales pour l'administration d'antibiotiques macrolides
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CN106589023A (zh) * 2016-11-22 2017-04-26 宜昌东阳光药业股份有限公司 一种罗红霉素杂质及其合成方法
WO2018178041A1 (fr) 2017-03-30 2018-10-04 F. Hoffmann-La Roche Ag Nouveaux composés pyrido[2,3-b]indole pour le traitement et la prophylaxie d'une infection bactérienne

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds

Also Published As

Publication number Publication date
EP1824870A1 (fr) 2007-08-29
RU2007121581A (ru) 2008-12-20
IL182978A0 (en) 2007-08-19
JP2008519788A (ja) 2008-06-12
WO2006050942A1 (fr) 2006-05-18
PE20061137A1 (es) 2006-12-13
KR20070085919A (ko) 2007-08-27
US20080090773A1 (en) 2008-04-17
NO20072939L (no) 2007-08-08
BRPI0517792A (pt) 2008-10-21
MX2007005776A (es) 2007-07-16
GB0424959D0 (en) 2004-12-15
CN101098881A (zh) 2008-01-02
ZA200703603B (en) 2008-07-30
US20080269146A1 (en) 2008-10-30
AU2005303961A1 (en) 2006-05-18
TW200630378A (en) 2006-09-01
CA2587413A1 (fr) 2006-05-18
AR053311A1 (es) 2007-05-02
US7718621B2 (en) 2010-05-18

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