MA27745A1 - Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci. - Google Patents

Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci.

Info

Publication number
MA27745A1
MA27745A1 MA28485A MA28485A MA27745A1 MA 27745 A1 MA27745 A1 MA 27745A1 MA 28485 A MA28485 A MA 28485A MA 28485 A MA28485 A MA 28485A MA 27745 A1 MA27745 A1 MA 27745A1
Authority
MA
Morocco
Prior art keywords
benzoylureidopyridyl
piperidine
substituted
acid derivatives
producing
Prior art date
Application number
MA28485A
Other languages
English (en)
Inventor
Karl Schoenafinger
Dieter Kadereit
Elisabeth Defossa
Andreas Herling
Thomas Klabunde
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MA27745A1 publication Critical patent/MA27745A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention se rapporte à des composés de formule (I) dans laquelle les groupes ont la signification indiquée dans la description, ainsi qu'à leurs sels physiologiquement acceptables. Ces composés peuvent par exemple servir de médicaments pour prévenir et traiter un diabète de type 2.
MA28485A 2003-03-07 2005-09-07 Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci. MA27745A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10309929A DE10309929B4 (de) 2003-03-07 2003-03-07 Substituierte Benzoylureidopyridyl-piperidin- und -pyrrolidin-carbonsäurederivate, Verfahren zu deren Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
MA27745A1 true MA27745A1 (fr) 2006-02-01

Family

ID=32945839

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28485A MA27745A1 (fr) 2003-03-07 2005-09-07 Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci.

Country Status (18)

Country Link
EP (1) EP1603895B1 (fr)
JP (1) JP2006519795A (fr)
KR (1) KR20050108487A (fr)
CN (1) CN1759109A (fr)
AT (1) ATE386735T1 (fr)
AU (1) AU2004218267A1 (fr)
BR (1) BRPI0408148A (fr)
CA (1) CA2518322A1 (fr)
CO (1) CO5690587A2 (fr)
DE (2) DE10309929B4 (fr)
HR (1) HRP20050779A2 (fr)
MA (1) MA27745A1 (fr)
MX (1) MXPA05009122A (fr)
NO (1) NO20054418L (fr)
PL (1) PL377293A1 (fr)
RU (1) RU2005131011A (fr)
WO (1) WO2004078743A1 (fr)
ZA (1) ZA200506119B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226942B2 (en) 2004-11-15 2007-06-05 Bristol-Myers Squibb Company 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7365061B2 (en) 2004-11-15 2008-04-29 Bristol-Myers Squibb Company 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
WO2006053274A2 (fr) 2004-11-15 2006-05-18 Bristol-Myers Squibb Company Derives de tetraline 2-amino-1-fonctionnalises et inhibiteurs correspondants de glycogene phosphorylase
WO2006055435A1 (fr) 2004-11-15 2006-05-26 Bristol-Myers Squibb Company Derives de 2-aminonaphtalene et inhibiteurs de la glycogene phosphorylase associes
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EP2486005B1 (fr) * 2009-10-06 2014-06-18 Bristol-Myers Squibb Company Modulateurs du gpr40 à base de pyrrolidine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3034004A1 (de) * 1980-09-10 1982-04-22 Hoechst Ag, 6000 Frankfurt Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung
YU91002A (sh) * 2000-06-09 2006-05-25 Aventis Pharma Deutschland Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka
DE10116768A1 (de) * 2001-04-04 2002-10-10 Aventis Pharma Gmbh Acylphenylharnstoffderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PE20021091A1 (es) * 2001-05-25 2003-02-04 Aventis Pharma Gmbh Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion
DE10125567B4 (de) * 2001-05-25 2004-08-26 Aventis Pharma Deutschland Gmbh Carbonamid substituierte Phenylharnstoffderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10215907A1 (de) * 2002-04-11 2003-11-06 Aventis Pharma Gmbh Acyl-4-carboxyphenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung
JP4374428B2 (ja) * 2002-07-11 2009-12-02 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 尿素置換されたおよびウレタン置換されたアシル尿素、それらの製造方法および医薬としてのそれらの使用方法
PL373329A1 (en) * 2002-07-12 2005-08-22 Sanofi-Aventis Deutschland Gmbh Heterocyclically substituted benzoylureas, method for their production and their use as medicaments

Also Published As

Publication number Publication date
HRP20050779A2 (en) 2006-10-31
KR20050108487A (ko) 2005-11-16
EP1603895B1 (fr) 2008-02-20
RU2005131011A (ru) 2006-05-10
DE502004006253D1 (de) 2008-04-03
EP1603895A1 (fr) 2005-12-14
MXPA05009122A (es) 2005-10-20
CO5690587A2 (es) 2006-10-31
ZA200506119B (en) 2006-11-29
BRPI0408148A (pt) 2006-03-01
NO20054418L (no) 2005-09-23
DE10309929B4 (de) 2006-02-23
CN1759109A (zh) 2006-04-12
JP2006519795A (ja) 2006-08-31
DE10309929A1 (de) 2004-12-02
AU2004218267A1 (en) 2004-09-16
PL377293A1 (pl) 2006-01-23
WO2004078743A1 (fr) 2004-09-16
ATE386735T1 (de) 2008-03-15
CA2518322A1 (fr) 2004-09-16

Similar Documents

Publication Publication Date Title
RS20050019A (en) Heterocyclically substituted benzoylureas,method for their production and their use as medicaments
IL176914A0 (en) Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments
NO20050134L (no) Difenylazetidioner substituert med syregrupper, fremgangsmate for fremstilling av disse, medikamenter inneholdende disse forbindelser og deres anvendelse
YU70901A (sh) Derivati 1,4-benzotiazepin-1,1 dioksida zamenjeni radikalima šećera, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena
TNSN06409A1 (en) Novel fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, and the use thereof
MXPA02011458A (es) Derivados de acilfenilurea, metodos para su produccion y uso de los mismos como farmacos.
BG108318A (en) Carboxamide-substituted phenylurea derivatives and method for the production and use thereof as medicaments
SE0102299D0 (sv) Compounds
SE0102300D0 (sv) Compounds
HRP20050870A2 (en) Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter
MA28340A1 (fr) Derives de l'acide 7- amino-4- quinolone-3-carboxylique substitues par un groupe cycloalkyle, methode pour leur production et leur utilisation en tant que medicaments
TW200510333A (en) Benzimidazole compounds
MA27745A1 (fr) Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci.
MA27232A1 (fr) Derives d'acide n-benzoylureidocinnamique, leurs procedes de preparation et leurs utilisations
MA27649A1 (fr) Derives d'acylphenyluree substitues par carbonylamino, methode de production et d'utilisation de ceux-ci.
TNSN06233A1 (en) 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments
ATE424195T1 (de) Verwendung von 2-amino-1,3-propandiolderivaten zur herstellung eines medikaments zur behandlung von bestimmten schmerzen
BR0312586A (pt) Derivados de pirolidina como antagonistas e oxitocina
MXPA05008331A (es) Derivados de 3-(benzoilureido)-tiofeno sustituido, metodo para su produccion y uso de los mismos.
ATE369849T1 (de) Haloacetamidobenzoesäure derivate und deren verwendung zur behandlung von parasitären erkrankungen
DE60209122D1 (de) Bernsteinsäurederivate
TNSN05008A1 (en) Heterocyclically substituted benzoylureas, method for their production and their use as medicaments.
DE50310168D1 (de) Polyisoprenyl-benzophenon-derivate, verfahren zu ihrer herstellung und verwendung derselben