MA27671A1 - Compositions pharmaceutiques comprenant une combinaison de rapamycine ou de son derive et de pimecrolimus pour le traitement de maladies inflammatoires et de maladies induites immunologiquement - Google Patents

Compositions pharmaceutiques comprenant une combinaison de rapamycine ou de son derive et de pimecrolimus pour le traitement de maladies inflammatoires et de maladies induites immunologiquement

Info

Publication number
MA27671A1
MA27671A1 MA28526A MA28526A MA27671A1 MA 27671 A1 MA27671 A1 MA 27671A1 MA 28526 A MA28526 A MA 28526A MA 28526 A MA28526 A MA 28526A MA 27671 A1 MA27671 A1 MA 27671A1
Authority
MA
Morocco
Prior art keywords
rapamycin
treatment
combination
pharmaceutical compositions
derivative
Prior art date
Application number
MA28526A
Other languages
English (en)
Inventor
Henrietta Moore
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33032928&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA27671(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0306070A external-priority patent/GB0306070D0/en
Priority claimed from GB0306868A external-priority patent/GB0306868D0/en
Priority claimed from GB0319226A external-priority patent/GB0319226D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA27671A1 publication Critical patent/MA27671A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention porte sur des compositions pharmaceutiques comprenant en combinaison la rapamycine ou un dérivé de rapamycine et un composé de formule (I), ces compositions pouvant être utiles dans le traitement de maladies inflammatoires et de maladies induites immunologiquement, telles que les maladies auto-immunes.
MA28526A 2003-03-17 2005-09-30 Compositions pharmaceutiques comprenant une combinaison de rapamycine ou de son derive et de pimecrolimus pour le traitement de maladies inflammatoires et de maladies induites immunologiquement MA27671A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0306070A GB0306070D0 (en) 2003-03-17 2003-03-17 Organic compounds
GB0306868A GB0306868D0 (en) 2003-03-25 2003-03-25 Organic compounds
GB0319226A GB0319226D0 (en) 2003-08-15 2003-08-15 Organic compounds

Publications (1)

Publication Number Publication Date
MA27671A1 true MA27671A1 (fr) 2005-12-01

Family

ID=33032928

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28526A MA27671A1 (fr) 2003-03-17 2005-09-30 Compositions pharmaceutiques comprenant une combinaison de rapamycine ou de son derive et de pimecrolimus pour le traitement de maladies inflammatoires et de maladies induites immunologiquement

Country Status (26)

Country Link
US (1) US20060154952A1 (fr)
EP (1) EP1608368B8 (fr)
JP (1) JP2006515017A (fr)
KR (1) KR100855140B1 (fr)
AR (1) AR043504A1 (fr)
AT (1) ATE409479T1 (fr)
AU (1) AU2004222563B2 (fr)
BR (1) BRPI0408423A (fr)
CA (2) CA2633287A1 (fr)
CL (1) CL2004000535A1 (fr)
DE (1) DE602004016830D1 (fr)
EC (1) ECSP056006A (fr)
ES (1) ES2315648T3 (fr)
HK (1) HK1086743A1 (fr)
HR (1) HRP20050800A2 (fr)
IS (1) IS8028A (fr)
MA (1) MA27671A1 (fr)
MX (1) MXPA05009934A (fr)
MY (1) MY137868A (fr)
NO (1) NO20054778L (fr)
PE (1) PE20050313A1 (fr)
PL (1) PL1608368T3 (fr)
PT (1) PT1608368E (fr)
TN (1) TNSN05197A1 (fr)
TW (2) TW200835484A (fr)
WO (1) WO2004082681A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1804779A1 (fr) * 2004-10-28 2007-07-11 Wyeth Utilisation d'un inhibiteur mtor dans le traitement de leiomyomes uterins
CA2719134C (fr) * 2008-03-21 2015-06-30 The University Of Chicago Traitement avec des antagonistes des opioides et des inhibiteurs mtor
AU2013205002B2 (en) * 2008-03-21 2016-09-15 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
ES2825173T3 (es) 2009-01-21 2021-05-14 Amgen Inc Composiciones y métodos de tratamiento de enfermedades inflamatorias y autoinmunitarias
RU2449806C1 (ru) * 2010-11-30 2012-05-10 Государственное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" Способ лечения красного плоского лишая слизистой оболочки полости рта
WO2014117035A1 (fr) 2013-01-24 2014-07-31 Transderm, Inc. Compositions pour une administration transdermique d'inhibiteurs de mtor
RU2707285C2 (ru) 2013-10-08 2019-11-26 ЭйАй ТЕРАПЬЮТИКС, ИНК. Рапамицин для лечения лимфангиолейомиоматоза
HRP20230863T1 (hr) * 2014-04-04 2023-11-10 AI Therapeutics, Inc. Inhalacijska formulacija rapamicina, namijenjena liječenju stanja povezanih sa starenjem
EP3209330B1 (fr) 2014-10-07 2022-02-23 AI Therapeutics, Inc. Formulation inhalable comprenant du sirolimus pour le traitement de l'hypertension pulmonaire
TN2017000432A1 (en) 2015-04-10 2019-04-12 Amgen Inc Interleukin-2 muteins for the expansion of t-regulatory cells
CA3049402A1 (fr) 2017-01-06 2018-07-12 Palvella Therapeutics Llc Compositions anhydres d'inhibiteurs de mtor et methodes d'utilisation
EP3817743A4 (fr) 2018-07-02 2022-07-06 Palvella Therapeutics, Inc. Compositions anhydres d'inhibiteurs de mtor et méthodes d'utilisation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU640963B2 (en) * 1989-11-09 1993-09-09 MEDA Pharma S.a.r.l Heteroatoms-containing tricyclic compounds
GB9221220D0 (en) * 1992-10-09 1992-11-25 Sandoz Ag Organic componds
FR2736550B1 (fr) * 1995-07-14 1998-07-24 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
PT956034E (pt) * 1996-07-30 2002-12-31 Novartis Ag Composicoes farmaceuticas para o tratamento da rejeicao de transplantes estados inflamatorios ou auto-imunes compreendendo ciclosporina a e 40-o-(2-hidroxietil)-rapamicina
GB9723669D0 (en) * 1997-11-07 1998-01-07 Univ Aberdeen Skin penetration enhancing components
JP2005512946A (ja) * 2001-05-09 2005-05-12 ノバルティス アクチエンゲゼルシャフト 選択的免疫調節法
CN1615137A (zh) * 2002-01-10 2005-05-11 诺瓦提斯公司 用于预防和治疗血管疾病、包含雷帕霉素及其衍生物的药物递送***
AU2003240391B8 (en) * 2002-05-09 2009-08-06 Hemoteq Ag Compounds and method for coating surfaces in a haemocompatible manner

Also Published As

Publication number Publication date
ES2315648T3 (es) 2009-04-01
AU2004222563B2 (en) 2006-11-02
KR100855140B1 (ko) 2008-08-28
CA2633287A1 (fr) 2004-09-30
JP2006515017A (ja) 2006-05-18
EP1608368B1 (fr) 2008-10-01
EP1608368A1 (fr) 2005-12-28
MXPA05009934A (es) 2006-03-21
DE602004016830D1 (de) 2008-11-13
KR20050110023A (ko) 2005-11-22
CL2004000535A1 (es) 2005-01-14
PT1608368E (pt) 2009-01-27
HK1086743A1 (en) 2006-09-29
AU2004222563A1 (en) 2004-09-30
HRP20050800A2 (en) 2006-11-30
NO20054778L (no) 2005-12-19
CA2517671A1 (fr) 2004-09-30
TW200835484A (en) 2008-09-01
ECSP056006A (es) 2006-01-27
ATE409479T1 (de) 2008-10-15
WO2004082681B1 (fr) 2004-11-25
PE20050313A1 (es) 2005-06-14
AR043504A1 (es) 2005-08-03
TW200503703A (en) 2005-02-01
IS8028A (is) 2005-09-15
EP1608368B8 (fr) 2009-06-10
WO2004082681A1 (fr) 2004-09-30
BRPI0408423A (pt) 2006-03-21
TNSN05197A1 (en) 2007-06-11
US20060154952A1 (en) 2006-07-13
MY137868A (en) 2009-03-31
PL1608368T3 (pl) 2009-03-31
NO20054778D0 (no) 2005-10-17

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