MA23753A1 - Procede de preparation de derives de piperidine nouveaux et de compositions pharmaceutiques contenant ces composes - Google Patents

Procede de preparation de derives de piperidine nouveaux et de compositions pharmaceutiques contenant ces composes

Info

Publication number
MA23753A1
MA23753A1 MA24106A MA24106A MA23753A1 MA 23753 A1 MA23753 A1 MA 23753A1 MA 24106 A MA24106 A MA 24106A MA 24106 A MA24106 A MA 24106A MA 23753 A1 MA23753 A1 MA 23753A1
Authority
MA
Morocco
Prior art keywords
compounds
preparation
pharmaceutical compositions
compositions containing
piperidine derivatives
Prior art date
Application number
MA24106A
Other languages
English (en)
Inventor
David King Francis
Adrian Wyman Paul
Mary Gaster Laramie
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9426029.6A external-priority patent/GB9426029D0/en
Priority claimed from GBGB9512920.1A external-priority patent/GB9512920D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of MA23753A1 publication Critical patent/MA23753A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
MA24106A 1994-12-22 1995-12-20 Procede de preparation de derives de piperidine nouveaux et de compositions pharmaceutiques contenant ces composes MA23753A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426029.6A GB9426029D0 (en) 1994-12-22 1994-12-22 Novel compounds
GBGB9512920.1A GB9512920D0 (en) 1995-06-24 1995-06-24 Novel compounds

Publications (1)

Publication Number Publication Date
MA23753A1 true MA23753A1 (fr) 1996-07-01

Family

ID=26306239

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24106A MA23753A1 (fr) 1994-12-22 1995-12-20 Procede de preparation de derives de piperidine nouveaux et de compositions pharmaceutiques contenant ces composes

Country Status (27)

Country Link
US (1) US5972951A (fr)
EP (1) EP0799226B1 (fr)
JP (1) JPH10510821A (fr)
CN (1) CN1175256A (fr)
AP (1) AP757A (fr)
AR (1) AR002011A1 (fr)
AT (1) ATE199085T1 (fr)
AU (1) AU697361B2 (fr)
BG (1) BG61977B1 (fr)
BR (1) BR9510419A (fr)
CA (1) CA2208244A1 (fr)
CZ (1) CZ192397A3 (fr)
DE (1) DE69520075T2 (fr)
DZ (1) DZ1957A1 (fr)
ES (1) ES2153907T3 (fr)
FI (1) FI972583A (fr)
HU (1) HUT77650A (fr)
IL (1) IL116486A0 (fr)
MA (1) MA23753A1 (fr)
MX (1) MX9704777A (fr)
NO (1) NO972910L (fr)
NZ (1) NZ298036A (fr)
OA (1) OA10610A (fr)
PL (1) PL321048A1 (fr)
SK (1) SK80297A3 (fr)
TR (1) TR199501597A2 (fr)
WO (1) WO1996019477A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9519033D0 (en) * 1995-09-18 1995-11-15 Smithkline Beecham Plc Treatment
WO1997017351A1 (fr) * 1995-11-08 1997-05-15 Smithkline Beecham Plc Derives spiro piperidine en tant qu'antagonistes du recepteur de 5mt
GB9522845D0 (en) * 1995-11-08 1996-01-10 Smithkline Beecham Plc Novel compounds
WO1997019070A1 (fr) * 1995-11-22 1997-05-29 Smithkline Beecham Plc Composes spiro tricycliques utiles comme antagonistes du recepteur 5ht¿1d?
GB9605883D0 (en) * 1996-03-20 1996-05-22 Smithkline Beecham Plc Novel compounds
GB9606396D0 (en) * 1996-03-27 1996-06-05 Smithkline Beecham Plc Novel compounds
US6156783A (en) * 1996-04-30 2000-12-05 Smithkline Beecham P.L.C. Spiroazabicyclic compounds, processes for their preparation, and their pharmaceutical use
FR2761069A1 (fr) * 1997-03-20 1998-09-25 Pf Medicament Spiroamines derivees de dihydrobenzofuranes, leur preparation et leur application comme medicaments
CA2347095A1 (fr) * 1998-10-16 2000-04-27 Takeda Chemical Industries, Ltd. Composes azotes hererocycliques condenses; procede de fabrication et agents les renfermant
DE10051981A1 (de) 2000-10-20 2002-05-02 Bayer Ag Substituierte Phenyluracile
US7144911B2 (en) 2002-12-31 2006-12-05 Deciphera Pharmaceuticals Llc Anti-inflammatory medicaments
US7202257B2 (en) 2003-12-24 2007-04-10 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
US7279576B2 (en) 2002-12-31 2007-10-09 Deciphera Pharmaceuticals, Llc Anti-cancer medicaments
US6969726B2 (en) * 2003-06-03 2005-11-29 Rib X Pharmaceuticals Inc Biaryl heterocyclic compounds and methods of making and using the same
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
EP1975149B1 (fr) 2005-12-26 2012-02-15 Nissan Chemical Industries, Ltd. Compose de 1,3-bis(phenyle substitue)-3-hydroxypropan-1-one ou 2-propen-1-one et son sel
EP2146717A4 (fr) 2007-04-20 2010-08-11 Deciphera Pharmaceuticals Llc Inhibiteurs de kinase utiles pour le traitement des maladies myléoprolifératives et d'autres maladies prolifératives
US7858666B2 (en) 2007-06-08 2010-12-28 Mannkind Corporation IRE-1α inhibitors
WO2009001942A1 (fr) 2007-06-27 2008-12-31 Nissan Chemical Industries, Ltd. Procédé de production du composé 3-hydroxypropane-1-one, procédé de production du composé 2-propène-1-one et procédé de production d'un composé d'isoxazoline
SI2350090T1 (sl) 2008-10-17 2015-10-30 Xenon Pharmaceuticals Inc. Spojine spiro-oksindola in njihova uporaba kot terapevtska sredstva
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
KR20120099429A (ko) 2009-10-14 2012-09-10 제논 파마슈티칼스 인크. 스피로-옥스인돌 화합물의 합성 방법
PE20121699A1 (es) 2010-02-26 2012-12-22 Xenon Pharmaceuticals Inc Composiciones farmaceuticas del compuesto espiro-oxindol para administracion topica
US8461179B1 (en) 2012-06-07 2013-06-11 Deciphera Pharmaceuticals, Llc Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
TW201636017A (zh) 2015-02-05 2016-10-16 梯瓦製藥國際有限責任公司 以螺吲哚酮化合物之局部調配物治療帶狀疱疹後遺神經痛之方法
WO2019036024A1 (fr) 2017-08-17 2019-02-21 Bristol-Myers Squibb Company Dérivés de 2-(1,1'-biphényl)-1h-benzo[d]imidazole et composés apparentés en tant qu'agonistes d'apéline et d'apj pour le traitement de maladies cardiovasculaires
WO2020183011A1 (fr) 2019-03-14 2020-09-17 Institut Curie Inhibiteurs de htr1d et leurs utilisations dans le traitement du cancer
MX2022001863A (es) 2019-08-12 2022-05-30 Deciphera Pharmaceuticals Llc Metodos para tratar los tumores del estroma gastrointestinal.
TW202122082A (zh) 2019-08-12 2021-06-16 美商迪賽孚爾製藥有限公司 治療胃腸道基質瘤方法
IL293864A (en) 2019-12-30 2022-08-01 Deciphera Pharmaceuticals Llc Preparations of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3- phenylurea
LT4084778T (lt) 2019-12-30 2024-01-25 Deciphera Pharmaceuticals, Llc Amorfinės kinazės inhibitoriaus vaistinės formos ir jų panaudojimo būdai
US11779572B1 (en) 2022-09-02 2023-10-10 Deciphera Pharmaceuticals, Llc Methods of treating gastrointestinal stromal tumors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9119932D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
ATE204262T1 (de) 1991-09-18 2001-09-15 Glaxo Group Ltd Benzanilidderivate als 5-ht1d-antagonisten

Also Published As

Publication number Publication date
OA10610A (en) 2002-09-06
CN1175256A (zh) 1998-03-04
SK80297A3 (en) 1998-12-02
AU4343396A (en) 1996-07-10
DE69520075T2 (de) 2001-08-02
AU697361B2 (en) 1998-10-01
AP9701006A0 (en) 1997-07-31
DZ1957A1 (fr) 2002-02-17
WO1996019477A1 (fr) 1996-06-27
NZ298036A (en) 1998-11-25
ATE199085T1 (de) 2001-02-15
BG101715A (en) 1998-02-27
US5972951A (en) 1999-10-26
CZ192397A3 (en) 1997-09-17
JPH10510821A (ja) 1998-10-20
HUT77650A (hu) 1998-07-28
AR002011A1 (es) 1998-01-07
MX9704777A (es) 1997-10-31
NO972910L (no) 1997-08-14
IL116486A0 (en) 1997-08-14
CA2208244A1 (fr) 1996-06-27
AP757A (en) 1999-09-06
BG61977B1 (bg) 1998-11-30
TR199501597A2 (tr) 1996-07-21
NO972910D0 (no) 1997-06-20
DE69520075D1 (de) 2001-03-15
BR9510419A (pt) 1998-05-19
FI972583A0 (fi) 1997-06-17
FI972583A (fi) 1997-08-19
PL321048A1 (en) 1997-11-24
EP0799226B1 (fr) 2001-02-07
ES2153907T3 (es) 2001-03-16
EP0799226A1 (fr) 1997-10-08

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