MA20150280A2 - Dérivés d'aryléthynyle - Google Patents
Dérivés d'aryléthynyleInfo
- Publication number
- MA20150280A2 MA20150280A2 MA37795A MA37795A MA20150280A2 MA 20150280 A2 MA20150280 A2 MA 20150280A2 MA 37795 A MA37795 A MA 37795A MA 37795 A MA37795 A MA 37795A MA 20150280 A2 MA20150280 A2 MA 20150280A2
- Authority
- MA
- Morocco
- Prior art keywords
- derivatives
- arylethynyl
- arylethynyl derivatives
- formula
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Abstract
La présente invention concerne des dérivés d'éthynyle de formule (i) dans laquelle r
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12176662 | 2012-07-17 | ||
| PCT/EP2013/064747 WO2014012851A1 (fr) | 2012-07-17 | 2013-07-12 | Dérivés d'aryléthynyle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA20150280A2 true MA20150280A2 (fr) | 2015-08-31 |
Family
ID=48782352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA37795A MA20150280A2 (fr) | 2012-07-17 | 2013-07-12 | Dérivés d'aryléthynyle |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US20150133505A1 (fr) |
| EP (1) | EP2875000B1 (fr) |
| JP (1) | JP6089104B2 (fr) |
| KR (1) | KR101631041B1 (fr) |
| CN (1) | CN104364233B (fr) |
| AR (1) | AR091764A1 (fr) |
| AU (1) | AU2013292142B2 (fr) |
| BR (1) | BR112014029015A2 (fr) |
| CA (1) | CA2871389C (fr) |
| CL (1) | CL2014003160A1 (fr) |
| CO (1) | CO7111256A2 (fr) |
| CR (1) | CR20140531A (fr) |
| CY (1) | CY1118205T1 (fr) |
| DK (1) | DK2875000T3 (fr) |
| EA (1) | EA026593B1 (fr) |
| ES (1) | ES2600133T3 (fr) |
| HK (1) | HK1202544A1 (fr) |
| HR (1) | HRP20161691T1 (fr) |
| HU (1) | HUE030177T2 (fr) |
| IL (1) | IL236362A (fr) |
| LT (1) | LT2875000T (fr) |
| MA (1) | MA20150280A2 (fr) |
| MX (1) | MX358998B (fr) |
| MY (1) | MY167810A (fr) |
| NZ (1) | NZ701849A (fr) |
| PE (1) | PE20150184A1 (fr) |
| PH (1) | PH12014502695B1 (fr) |
| PL (1) | PL2875000T3 (fr) |
| PT (1) | PT2875000T (fr) |
| RS (1) | RS55313B1 (fr) |
| SG (1) | SG11201407050UA (fr) |
| SI (1) | SI2875000T1 (fr) |
| TW (1) | TWI473799B (fr) |
| UA (1) | UA114911C2 (fr) |
| WO (1) | WO2014012851A1 (fr) |
| ZA (1) | ZA201408514B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA113223C2 (xx) * | 2012-08-13 | 2016-12-26 | Арилетинілпіримідини | |
| NZ703537A (en) * | 2012-10-18 | 2018-06-29 | Hoffmann La Roche | Ethynyl derivatives |
| CN107849006B (zh) | 2015-06-03 | 2020-11-13 | 豪夫迈·罗氏有限公司 | 乙炔基衍生物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19546462A1 (de) * | 1995-12-13 | 1997-06-19 | Bayer Ag | Diarylacetylenketone |
| SI1354875T1 (en) | 2003-05-19 | 2005-02-28 | Les Laboratoires Servier | Method for synthesis of (2S,3aS,7aS)-perhydroindole-2-carboxylic acid and esters thereof; and use in the synthesis of perindopril |
| GB0325956D0 (en) | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
| EP1809620B1 (fr) | 2004-11-04 | 2010-12-29 | Addex Pharma SA | Nouveaux derives de tetrazole utilises comme modulateurs allosteriques positifs des recepteurs de glutamate metabotropiques |
| GB0510139D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
| WO2008151184A1 (fr) | 2007-06-03 | 2008-12-11 | Vanderbilt University | Dérivés benzamides modulateurs allostériques positifs récepteurs métabotropiques du glutamate 5 (mglur5) et leurs procédés de fabrication et d'utilisation |
| CN101544892B (zh) * | 2009-05-07 | 2012-10-03 | 石家庄诚志永华显示材料有限公司 | 一种合成二芳基乙炔类单体液晶的方法 |
| US8420661B2 (en) * | 2010-04-13 | 2013-04-16 | Hoffmann-La Roche Inc. | Arylethynyl derivatives |
| HUE025031T2 (en) * | 2011-04-26 | 2016-02-29 | Hoffmann La Roche | Ethinyl derivatives as positive allosteric modulators of MGLUR5 |
-
2013
- 2013-07-12 SI SI201330415A patent/SI2875000T1/sl unknown
- 2013-07-12 EP EP13735315.7A patent/EP2875000B1/fr active Active
- 2013-07-12 LT LTEP13735315.7T patent/LT2875000T/lt unknown
- 2013-07-12 DK DK13735315.7T patent/DK2875000T3/en active
- 2013-07-12 SG SG11201407050UA patent/SG11201407050UA/en unknown
- 2013-07-12 NZ NZ701849A patent/NZ701849A/en not_active IP Right Cessation
- 2013-07-12 JP JP2015521004A patent/JP6089104B2/ja active Active
- 2013-07-12 BR BR112014029015A patent/BR112014029015A2/pt not_active Application Discontinuation
- 2013-07-12 AU AU2013292142A patent/AU2013292142B2/en not_active Ceased
- 2013-07-12 CA CA2871389A patent/CA2871389C/fr not_active Expired - Fee Related
- 2013-07-12 PL PL13735315T patent/PL2875000T3/pl unknown
- 2013-07-12 RS RS20160979A patent/RS55313B1/sr unknown
- 2013-07-12 MX MX2014014950A patent/MX358998B/es active IP Right Grant
- 2013-07-12 MY MYPI2014003059A patent/MY167810A/en unknown
- 2013-07-12 HU HUE13735315A patent/HUE030177T2/en unknown
- 2013-07-12 PT PT137353157T patent/PT2875000T/pt unknown
- 2013-07-12 WO PCT/EP2013/064747 patent/WO2014012851A1/fr active Application Filing
- 2013-07-12 EA EA201492274A patent/EA026593B1/ru not_active IP Right Cessation
- 2013-07-12 ES ES13735315.7T patent/ES2600133T3/es active Active
- 2013-07-12 KR KR1020157001019A patent/KR101631041B1/ko active IP Right Grant
- 2013-07-12 CN CN201380031736.9A patent/CN104364233B/zh active Active
- 2013-07-12 UA UAA201500231A patent/UA114911C2/uk unknown
- 2013-07-12 PE PE2014002231A patent/PE20150184A1/es active IP Right Grant
- 2013-07-12 MA MA37795A patent/MA20150280A2/fr unknown
- 2013-07-15 AR ARP130102507 patent/AR091764A1/es not_active Application Discontinuation
- 2013-07-16 TW TW102125419A patent/TWI473799B/zh not_active IP Right Cessation
-
2014
- 2014-10-23 CO CO14235289A patent/CO7111256A2/es unknown
- 2014-11-19 ZA ZA2014/08514A patent/ZA201408514B/en unknown
- 2014-11-20 CR CR20140531A patent/CR20140531A/es unknown
- 2014-11-21 CL CL2014003160A patent/CL2014003160A1/es unknown
- 2014-12-03 PH PH12014502695A patent/PH12014502695B1/en unknown
- 2014-12-18 IL IL236362A patent/IL236362A/en active IP Right Grant
-
2015
- 2015-01-15 US US14/597,375 patent/US20150133505A1/en not_active Abandoned
- 2015-03-31 HK HK15103216.5A patent/HK1202544A1/zh unknown
- 2015-10-26 US US14/923,308 patent/US9328090B2/en active Active
-
2016
- 2016-11-04 CY CY20161101133T patent/CY1118205T1/el unknown
- 2016-12-12 HR HRP20161691TT patent/HRP20161691T1/hr unknown
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