LV15231A - Method for production of n-[4-[2-(2-amino-4-okso-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid.
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Method for production of n-[4-[2-(2-amino-4-okso-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid.
Pharma And Chemistry Competence Centre Of Latvia, Sia
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The present invention pertains to pharmaceutical industry, particularly to industrially usable method for production of N-[4-[2-(2-amino-4-okso-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid (pemetrexed).
LVP-15-117A2015-10-262015-10-26Method for production of n-[4-[2-(2-amino-4-okso-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid.
LV15231A
(en)
Process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]-3-oxo-5,6,8,8a-tetrahydro-1h-imidazo[1,5-a]pyrazin-2-yl]-carboxylic acid
Polymorphs of 2-(4-(2-(1-isopropyl-3-methyl-1h-1,2,4-triazol-5-yl )-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1h-pyrazo l-1-yl)-2-methylpropanamide, methods of production, and pharmaceutical uses thereof.