LU82083A1 - Nouveaux derives du nor-tropane,leur procede de preparation et leur application en therapeutique - Google Patents

Nouveaux derives du nor-tropane,leur procede de preparation et leur application en therapeutique Download PDF

Info

Publication number: LU82083A1
Authority: LU; Luxembourg
Prior art keywords: formula; methoxy; amino; benzoyl; nucleus
Prior art date: 1979-01-16

Application number

LU82083A

Other languages

English (en)

French (fr)

Inventor

B Bucher

T Imbert

P Dostert

Original Assignee

Delalande Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-01-16

Filing date

1980-01-14

Publication date

1981-09-10

1979-01-16 Priority claimed from FR7900971A external-priority patent/FR2446823A1/fr

1980-01-14 Application filed by Delalande Sa filed Critical Delalande Sa

1981-09-10 Publication of LU82083A1 publication Critical patent/LU82083A1/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Furan Compounds (AREA)

LU82083A 1979-01-16 1980-01-14 Nouveaux derives du nor-tropane,leur procede de preparation et leur application en therapeutique LU82083A1 (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR7900971		1979-01-16
FR7900971A FR2446823A1 (fr)	1979-01-16	1979-01-16	Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
FR7931656		1979-12-26
FR7931656A FR2476088A2 (fr)	1979-01-16	1979-12-26	Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
LU82083A1 true LU82083A1 (fr)	1981-09-10

Family

ID=26220957

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU82083A LU82083A1 (fr)	1979-01-16	1980-01-14	Nouveaux derives du nor-tropane,leur procede de preparation et leur application en therapeutique

Country Status (14)

Country	Link
US (2)	US4471120A (nl)
AU (1)	AU542537B2 (nl)
BE (1)	BE881134A (nl)
CA (1)	CA1130286A (nl)
CH (2)	CH647520A5 (nl)
DE (2)	DE3049963C2 (nl)
ES (1)	ES487721A1 (nl)
FR (1)	FR2476088A2 (nl)
GB (1)	GB2042522B (nl)
GR (1)	GR66499B (nl)
IT (2)	IT1148801B (nl)
LU (1)	LU82083A1 (nl)
NL (1)	NL8000277A (nl)
SE (2)	SE444941B (nl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL61642A0 (en) *	1979-12-20	1981-01-30	Beecham Group Ltd	Aniline derivatives,their preparation and pharmalceutical compositions containing them
FR2493848B2 (fr) *	1980-11-07	1986-05-16	Delalande Sa	Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
ZA818221B (en) *	1980-12-12	1982-10-27	Beecham Group Plc	Pharmaceutical compounds
EP0069481A1 (en) *	1981-06-17	1983-01-12	Beecham Group Plc	Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
EP0067615B1 (en) *	1981-06-17	1986-01-08	Beecham Group Plc	Alkylthio derivatives of azabicyclobenzamides, their preparation and pharmaceutical compositions
EP0068700A1 (en) *	1981-06-29	1983-01-05	Beecham Group Plc	Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them
EP0069482A1 (en) *	1981-06-29	1983-01-12	Beecham Group Plc	Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
GB2111479A (en) *	1981-10-01	1983-07-06	Beecham Group Plc	Benzamides
EP0083737A1 (en) *	1981-12-15	1983-07-20	Beecham Group Plc	N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them
EP0095262B1 (en) *	1982-05-11	1986-12-03	Beecham Group Plc	Azabicycloalkane derivatives, their preparation and medicaments containing them
FR2531083B1 (fr) *	1982-06-29	1986-11-28	Sandoz Sa	Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
WO1984001151A1 (en) *	1982-09-24	1984-03-29	Beecham Group Plc	Amino-azabicycloalkyl derivatives as dopamine antagonists
CA1244028A (en) *	1983-04-14	1988-11-01	Hans Maag	Pyrimidine derivatives
FR2546169B1 (fr) *	1983-05-20	1986-03-21	Delalande Sa	N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
CH664567A5 (de) *	1983-08-26	1988-03-15	Sandoz Ag	Aromatische carbonsaeure- und sulfonsaeureester oder -amide.
FR2557110B1 (fr) *	1983-12-23	1989-11-24	Sandoz Sa	Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
US4997956A (en) *	1989-06-14	1991-03-05	Eli Lilly And Company	Certain 2,3-dihydro-2;2-dimethyl-benzothiophene carboxylic acids which are intermediates
US5364863A (en) *	1987-09-08	1994-11-15	Eli Lilly And Company	Specific 5-HT3 antagonists
US4921982A (en) *	1988-07-21	1990-05-01	Eli Lilly And Company	5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists
US5070094A (en) *	1989-09-05	1991-12-03	G. D. Searle & Co.	N-benzyltropaneamides
GB9027487D0 (en) *	1990-12-19	1991-02-06	Beecham Group Plc	Pharmaceuticals
FR2831884B1 (fr)	2001-11-02	2003-12-26	Pf Medicament	Nouveaux derives amides heteroaromatiques de 3 beta-amino azabicyclooctane, leur procede de preparation et leurs applications en therapeutique
CN100368409C (zh)	2003-06-24	2008-02-13	神经研究公司	8-氮杂双环[3.2.1]辛烷衍生物及其用于制备单胺神经递质再摄取抑制剂的用途
EP2268646B9 (en) *	2008-04-11	2014-11-19	Janssen Pharmaceutica, N.V.	Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase
KR101727650B1 (ko)	2009-05-14	2017-04-17	얀센 파마슈티카 엔.브이.	류코트리엔 ａ4 하이드롤라아제의 조절제로서의 2개의 융합된 바이사이클릭 헤테로아릴 부분을 갖는 화합물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3134782A (en) *		1964-05-26		Chjxch-
GB774858A (en) *	1954-10-20	1957-05-15	Sandoz Ltd	Tropane and -Î-tropane derivatives and process for preparation thereof
FR1162129A (fr) *	1954-10-20	1958-09-09	Sandoz Ag	Dérivés amidés du tropane et leur préparation
CH374679A (de) *	1958-11-26	1964-01-31	Sandoz Ag	Verfahren zur Herstellung von neuen Tropan-Derivaten
DE2513136C3 (de) *	1974-03-21	1981-04-30	Anphar S.A., Madrid	N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
GB1593146A (en) *	1976-11-05	1981-07-15	Beecham Group Ltd	Octahydro-quinolizinyl benzamide derivatives
US4179567A (en) *	1978-04-10	1979-12-18	Sterling Drug Inc.	2-Aryltropane compounds
IL59004A0 (en) *	1978-12-30	1980-03-31	Beecham Group Ltd	Substituted benzamides their preparation and pharmaceutical compositions containing them
US4329466A (en) *	1979-01-16	1982-05-11	Delalande S.A.	Certain nor-tropan-8-amine-3-aryl or heteroaryl derivatives
US4321378A (en) *	1979-01-16	1982-03-23	Delalande S.A.	8-(5-Pyrimidinecarboxamide)nor-tropane derivatives

1979
- 1979-12-26 FR FR7931656A patent/FR2476088A2/fr active Granted
1980
- 1980-01-04 SE SE8000068A patent/SE444941B/sv not_active IP Right Cessation
- 1980-01-05 GR GR60908A patent/GR66499B/el unknown
- 1980-01-07 US US06/110,067 patent/US4471120A/en not_active Expired - Lifetime
- 1980-01-08 CH CH111/80A patent/CH647520A5/fr not_active IP Right Cessation
- 1980-01-08 IT IT19071/80A patent/IT1148801B/it active
- 1980-01-08 CA CA343,219A patent/CA1130286A/en not_active Expired
- 1980-01-11 GB GB8001037A patent/GB2042522B/en not_active Expired
- 1980-01-14 LU LU82083A patent/LU82083A1/fr unknown
- 1980-01-14 BE BE0/198955A patent/BE881134A/fr not_active IP Right Cessation
- 1980-01-15 AU AU54610/80A patent/AU542537B2/en not_active Ceased
- 1980-01-15 ES ES487721A patent/ES487721A1/es not_active Expired
- 1980-01-16 NL NL8000277A patent/NL8000277A/nl not_active Application Discontinuation
- 1980-01-16 DE DE3049963A patent/DE3049963C2/de not_active Expired - Lifetime
- 1980-01-16 DE DE19803001328 patent/DE3001328A1/de active Granted
- 1980-08-12 SE SE8005674A patent/SE431984B/sv not_active IP Right Cessation
- 1980-08-18 CH CH622080A patent/CH646969A5/fr not_active IP Right Cessation
- 1980-09-17 IT IT8024713A patent/IT1235424B/it active
1982
- 1982-07-19 US US06/399,392 patent/US4536580A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NL8000277A (nl)	1980-07-18
IT8024713A0 (it)	1980-09-17
IT1235424B (it)	1992-07-09
US4536580A (en)	1985-08-20
GR66499B (nl)	1981-03-24
GB2042522B (en)	1983-04-13
FR2476088A2 (fr)	1981-08-21
IT8019071A0 (it)	1980-01-08
AU5461080A (en)	1980-07-24
US4471120A (en)	1984-09-11
CH646969A5 (fr)	1984-12-28
FR2476088B2 (nl)	1983-11-04
CA1130286A (en)	1982-08-24
SE444941B (sv)	1986-05-20
GB2042522A (en)	1980-09-24
AU542537B2 (en)	1985-02-28
SE431984B (sv)	1984-03-12
SE8000068L (sv)	1980-07-17
DE3001328C2 (nl)	1989-06-08
DE3001328A1 (de)	1980-07-24
IT1148801B (it)	1986-12-03
BE881134A (fr)	1980-07-14
ES487721A1 (es)	1980-06-16
CH647520A5 (fr)	1985-01-31
DE3049963C2 (de)	1993-11-25

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