KR970706280A - 5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists) - Google Patents

5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists)

Info

Publication number: KR970706280A
Authority: KR; South Korea
Prior art keywords: aryl; bicyclic; antagonists; formula; carboxamides
Prior art date: 1994-09-21

Application number

KR1019970701764A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-21

Filing date

1997-03-19

Publication date

1997-11-03

1997-03-19 Application filed filed Critical

1997-11-03 Publication of KR970706280A publication Critical patent/KR970706280A/ko

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

KR1019970701764A 1994-09-21 1997-03-19 5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists) KR970706280A (ko)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9419024A GB9419024D0 (en)	1994-09-21	1994-09-21	Bicyclic carboxamides
PCT/GB1995/002001 WO1996009302A1 (en)	1994-09-21	1995-08-23	Bicyclic carboxamides as 5-ht1a antagonists

Publications (1)

Publication Number	Publication Date
KR970706280A true KR970706280A (ko)	1997-11-03

Family

ID=10761683

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019970701764A KR970706280A (ko)	1994-09-21	1997-03-19	5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists)

Country Status (22)

Country	Link
US (1)	US5610154A (ko)
EP (1)	EP0782574B1 (ko)
JP (1)	JPH10505853A (ko)
KR (1)	KR970706280A (ko)
CN (1)	CN1043764C (ko)
AT (1)	ATE215083T1 (ko)
AU (1)	AU692917B2 (ko)
BR (1)	BR9508979A (ko)
CA (1)	CA2200443A1 (ko)
DE (1)	DE69526097D1 (ko)
DK (1)	DK0782574T3 (ko)
ES (1)	ES2170802T3 (ko)
FI (1)	FI971177A (ko)
GB (1)	GB9419024D0 (ko)
HU (1)	HUT77940A (ko)
IL (1)	IL115085A (ko)
MX (1)	MX9702089A (ko)
NZ (1)	NZ291855A (ko)
PT (1)	PT782574E (ko)
TW (1)	TW424092B (ko)
WO (1)	WO1996009302A1 (ko)
ZA (1)	ZA957449B (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5607936A (en) *	1994-09-30	1997-03-04	Merck & Co., Inc.	Substituted aryl piperazines as neurokinin antagonists
FR2756283A1 (fr) *	1996-11-27	1998-05-29	Pf Medicament	Amines aromatiques d'arylpiperazines, leur preparation et leurs applications comme medicaments
US5919802A (en) *	1997-12-05	1999-07-06	Princeton University	Methods of preventing and/or treating temporal lobe epilepsy
ITMI20021327A1 (it) *	2002-06-14	2003-12-15	Recordati Chem Pharm	Nuove ossialchilpiperazine
US20040153119A1 (en) *	2003-01-30	2004-08-05	Kusleika Richard S.	Embolic filters with a distal loop or no loop

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3422092A (en) *	1966-02-18	1969-01-14	Upjohn Co	2 - carbamoyl - 2-azabicyclo(2.2.2)octanes,and 3 - carbamoyl - 3 - azabicyclo(3.2.2) nonanes
KR0173310B1 (ko) *	1989-04-22	1999-02-01	폴 에이 리쳐	피페라진 유도체
GB9022820D0 (en) *	1990-10-19	1990-12-05	Wyeth John & Brother Ltd	Piperazine derivatives
GB9125900D0 (en) *	1991-12-05	1992-02-05	Wyeth John & Brother Ltd	Piperazine derivatives
GB9300195D0 (en) *	1993-01-06	1993-03-03	Wyeth John & Brother Ltd	Piperazine derivatives

1994
- 1994-09-21 GB GB9419024A patent/GB9419024D0/en active Pending
1995
- 1995-05-24 US US08/448,962 patent/US5610154A/en not_active Expired - Lifetime
- 1995-08-23 NZ NZ291855A patent/NZ291855A/xx unknown
- 1995-08-23 PT PT95929941T patent/PT782574E/pt unknown
- 1995-08-23 HU HU9800408A patent/HUT77940A/hu unknown
- 1995-08-23 EP EP95929941A patent/EP0782574B1/en not_active Expired - Lifetime
- 1995-08-23 AU AU33501/95A patent/AU692917B2/en not_active Ceased
- 1995-08-23 BR BR9508979A patent/BR9508979A/pt not_active Application Discontinuation
- 1995-08-23 JP JP8510658A patent/JPH10505853A/ja not_active Ceased
- 1995-08-23 ES ES95929941T patent/ES2170802T3/es not_active Expired - Lifetime
- 1995-08-23 MX MX9702089A patent/MX9702089A/es unknown
- 1995-08-23 DK DK95929941T patent/DK0782574T3/da active
- 1995-08-23 CN CN95195207A patent/CN1043764C/zh not_active Expired - Fee Related
- 1995-08-23 DE DE69526097T patent/DE69526097D1/de not_active Expired - Lifetime
- 1995-08-23 WO PCT/GB1995/002001 patent/WO1996009302A1/en not_active Application Discontinuation
- 1995-08-23 CA CA002200443A patent/CA2200443A1/en not_active Abandoned
- 1995-08-23 AT AT95929941T patent/ATE215083T1/de not_active IP Right Cessation
- 1995-08-28 IL IL11508595A patent/IL115085A/xx not_active IP Right Cessation
- 1995-09-05 ZA ZA957449A patent/ZA957449B/xx unknown
- 1995-09-19 TW TW084109809A patent/TW424092B/zh not_active IP Right Cessation
1997
- 1997-03-19 KR KR1019970701764A patent/KR970706280A/ko not_active Application Discontinuation
- 1997-03-20 FI FI971177A patent/FI971177A/fi unknown

Also Published As

Publication number	Publication date
NZ291855A (en)	1999-08-30
AU692917B2 (en)	1998-06-18
HUT77940A (hu)	1998-12-28
AU3350195A (en)	1996-04-09
PT782574E (pt)	2002-08-30
WO1996009302A1 (en)	1996-03-28
CA2200443A1 (en)	1996-03-28
EP0782574B1 (en)	2002-03-27
FI971177A0 (fi)	1997-03-20
JPH10505853A (ja)	1998-06-09
FI971177A (fi)	1997-05-20
ATE215083T1 (de)	2002-04-15
US5610154A (en)	1997-03-11
TW424092B (en)	2001-03-01
MX9702089A (es)	1997-06-28
EP0782574A1 (en)	1997-07-09
CN1043764C (zh)	1999-06-23
CN1158615A (zh)	1997-09-03
DE69526097D1 (de)	2002-05-02
ZA957449B (en)	1997-03-05
ES2170802T3 (es)	2002-08-16
IL115085A (en)	1999-06-20
IL115085A0 (en)	1995-12-08
BR9508979A (pt)	1997-10-28
GB9419024D0 (en)	1994-11-09
DK0782574T3 (da)	2002-05-06

Legal Events

Date	Code	Title
2000-08-09	A201	Request for examination
2002-08-27	E902	Notification of reason for refusal
2002-11-12	E601	Decision to refuse application

Publication	Publication Date	Title
MY107756A (en)	1996-06-15	Piperazine derivatives.
SE8704599D0 (sv)	1987-11-20	Teobrominderivat
ES2105617T3 (es)	1997-10-16	Derivados de piperacina como antagonistas de 5-ht.
MY117092A (en)	2004-05-31	Chemotherapeutic pyrrolocarbazole derivatives
DE69414855T2 (de)	1999-07-08	N-(piperidinyl-1-alkyl)-substituierte cyclohexancarbonsäureamide als 5ht1a rezeptor antagonisten
ES2123756T3 (es)	1999-01-16	Derivados de piperazina.
ATE224372T1 (de)	2002-10-15	Substituierte 6-alkylphenanthridine
NO971142L (no)	1997-03-12	Bis-(2-halogenetyl)aminofenylsubstituerte distamycinderivater som antitumor- og antivirale midler
KR970706280A (ko)	1997-11-03	5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists)
DE69431471D1 (de)	2002-11-07	Amide derivate als 5-ht1a liganden
NO994104L (no)	1999-10-26	5-hydroksymetyl-2-aminotetraliner i form av kardiovaskulaere midler
DK0687257T3 (da)	1997-08-18	4-amino-2-(hetero)aryl-butanamider anvendelige som 5HT1A-antagonister
DK428087A (da)	1987-08-17	Dihydropyridin-5-phosphonsyre-cyclopropylenester
ATE53839T1 (de)	1990-06-15	2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.