KR970020109A - Covalent conjugate of streptokinase and polysaccharide and preparation method thereof - Google Patents
Covalent conjugate of streptokinase and polysaccharide and preparation method thereof Download PDFInfo
- Publication number
- KR970020109A KR970020109A KR1019950036040A KR19950036040A KR970020109A KR 970020109 A KR970020109 A KR 970020109A KR 1019950036040 A KR1019950036040 A KR 1019950036040A KR 19950036040 A KR19950036040 A KR 19950036040A KR 970020109 A KR970020109 A KR 970020109A
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- KR
- South Korea
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- streptokinase
- polysaccharide
- covalent conjugate
- polysaccharides
- producing
- Prior art date
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- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
본 발명은 스트렙토키나제와 다당류를 결합시켜 얻은 공유결합체 및 그 제조 방법에 관한 것이다.The present invention relates to a covalent conjugate obtained by combining streptokinase and a polysaccharide and a method for producing the same.
본 발명의 스트렙토키나제와 다당류의 공유결합체는 다당류의 히드록시 메틸기를 산화시켜 알데히드가 반응기로서 부가된 다당류를 얻은 다음 스트렙토키나제와 쉬프염을 형성시킨 후 이를 환원시켜 제조한다.The covalent conjugate of the streptokinase and the polysaccharide of the present invention is prepared by oxidizing the hydroxy methyl group of the polysaccharide to obtain a polysaccharide to which aldehyde is added as a reactor, and then forming a Schiff salt with streptokinase and reducing it.
본 발명의 목적물은 체내 안정성 가와 항원성 감소는 물론 임상에 직접 사용할 수 있는 안전성도 높다.The object of the present invention has high stability in the body and antigenicity, as well as high safety that can be used directly in the clinic.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019950036040A KR970020109A (en) | 1995-10-18 | 1995-10-18 | Covalent conjugate of streptokinase and polysaccharide and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019950036040A KR970020109A (en) | 1995-10-18 | 1995-10-18 | Covalent conjugate of streptokinase and polysaccharide and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
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KR970020109A true KR970020109A (en) | 1997-05-28 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950036040A KR970020109A (en) | 1995-10-18 | 1995-10-18 | Covalent conjugate of streptokinase and polysaccharide and preparation method thereof |
Country Status (1)
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KR (1) | KR970020109A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010000669A (en) * | 2000-10-12 | 2001-01-05 | 김기환 | Streptokinase-Human serum albumin conjugate as long-acting thrombolytic agent |
-
1995
- 1995-10-18 KR KR1019950036040A patent/KR970020109A/en not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010000669A (en) * | 2000-10-12 | 2001-01-05 | 김기환 | Streptokinase-Human serum albumin conjugate as long-acting thrombolytic agent |
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